Protein Alignment bdg and SLC6A7

DIOPT Version :10

• Sequence 1: NP_611064.2
• Gene: bdg / 36747
• FlyBaseID: FBgn0034049
• Length: 1331
• Species: Drosophila melanogaster
• Sequence 2: XP_016865256.1
• Gene: SLC6A7 / 6534
• HGNCID: 11054
• Length: 754
• Species: Homo sapiens
• Alignment Length: 820
• Identity: 179/820 - (21%)
• Similarity: 308/820 - (37%)
• Gaps: 242/820 - (29%)

  Fly   373 PRPRQYGRRLEGPPTPVRPLILAQSR----PQSAPTRVQMREPQLQD------------------ 415
            |:||...|..:|..:.: |.:.|:||    |.|.|.....|||:.|.
Human     9 PQPRALRRDRQGIRSAL-PALHARSRQTAAPASVPAPAGAREPRGQRRSGQRTISRALALCAPGQ 72

  Fly   416 -TPTHPIMSTCSELSSARSSRMPSPVSLPSDSSSSGSSSAEHDQEPDPVQTTTMCSASSTTPLEP 479
             :|.||:    |::...:.:.:..||:  .|...:.|...:.|.:.|
Human    73 LSPGHPL----SKMKKLQGAHLRKPVT--PDLLMTPSDQGDVDLDVD------------------ 113

  Fly   480 LHQLQLLLREKCGFNSQWPHAGSRT------LALIGCTLGVFNMCRFAVLT-INFGGNFLLQFLL 537
                         |.:   |.|:.|      |:.||..:|:.|:.||.... .|.||.||:.:.|
Human   114 -------------FAA---HRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFL 162

  Fly   538 LSVIFGIPLLWLQMCLGAKIRAGPVSMWKISPICAGVGIALVMQQCFLALYSTVSLAWILVYLRD 602
            :..|.||||.:|::.||.....||:::|||||:..|.|.|:::....:|:|..:.:|::|.||.
Human   163 MLAICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLF- 226

  Fly   603 VFPTAARSGYRWQ--------EMAFPYRY--DASNATG-NLTQTVA---EYFN------------ 641
               .:..|...|:        |:...:|.  |.:.|.. |||.||:   ||::
Human   227 ---ASLTSDLPWEHCGNWWNTELCLEHRVSKDGNGALPLNLTCTVSPSEEYWSQTHTEAEEEGRR 288

  Fly   642 --VV---VLQRLHLANHPDA-SGIR---FHVNDRQ-----------LAFYLALIWAAVFLILCKG 686
              ||   ..|.:.|...|.| .|:.   .|:...|           |...|.|.|..|||.:.||
Human   289 GRVVSNSYPQVIFLPQPPKAEEGVSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKG 353

  Fly   687 LKSLGKLAYIIYTLPLVALAVVTAKFVYVVDPSRIQNIFAASDFDDFLVNSNSWTAATQETFLTW 751
            :||.||:.|...|.|.:.|.::..:.|.:....:....:....| ..|::|..|..|..:.|.:.
Human   354 VKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQF-HHLLSSKVWIEAALQIFYSL 417

  Fly   752 GLLGASVIAITSRSHTNANKAALRRDAILLVLFTLIGLGLMALLALCCAQILWQHGYVYVPGSFE 816
            |:....::...|.:..:.|   :.||..::.|    |..:.::||          |:
Human   418 GVGFGGLLTFASYNTFHQN---IYRDTFIVTL----GNAITSILA----------GF-------- 457

  Fly   817 NPDCYTSIYSLQSNTNPYLLSYPRSLIPHYSSFIGETYRRNRTMIHVESGFQA---LRFISEIFP 878
                  :|:               |::.:.|..:|         :.|:...:|   |.|:  ::|
Human   458 ------AIF---------------SVLGYMSQELG---------VPVDQVAKAGPGLAFV--VYP 490

  Fly   879 AVLSLASDSISWVWAAVAFATFAGFGLAQLCVMWKPISSALGNSTSSVL---------LSCVTGL 934
            ..:::.  .:|..|:.:.|......||.......:.|.:|:.:.....|         |.||...
Human   491 QAMTML--PLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAMY 553

  Fly   935 LLSIPFATEMGISILYYV----DFLLGGSWFIPIIWT----AQIFGVFLIRGRPYNGDDLVNDLR 991
            |:.:...|:.|   :|::    |:.......:.:|.|    .:::|:                .|
Human   554 LMGLILTTDGG---MYWLVLLDDYSASFGLMVVVITTCLAVTRVYGI----------------QR 599

  Fly   992 LCGSMSAFLALS--------WNVLLPIGLITL---SVVDYKASLSNQFYYWRGKSYFTYWSRKMG 1045
            .|..:...|...        |..|.|..|:.|   |:|.|:.|     .|  |...|..|:..:|
Human   600 FCRDIHMMLGFKPGLYFRACWLFLSPATLLALMVYSIVKYQPS-----EY--GSYRFPPWAELLG 657

  Fly  1046 SLIQIGVLLVIPVTAIIQIYRYLAHGPPDILERIQLLYRP 1085
            .|:.:...|:||...::.:.|  ..|  .:.||:|...||
Human   658 ILMGLLSCLMIPAGMLVAVLR--EEG--SLWERLQQASRP 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	123/547 (22%)
SLC6A7	XP_016865256.1	SLC6sbd_PROT	118..699	CDD:271390	151/670 (23%)