Protein Alignment bdg and slc6a8

DIOPT Version :10

• Sequence 1: NP_611064.2
• Gene: bdg / 36747
• FlyBaseID: FBgn0034049
• Length: 1331
• Species: Drosophila melanogaster
• Sequence 2: NP_001314797.1
• Gene: slc6a8 / 567544
• ZFINID: ZDB-GENE-071024-2
• Length: 652
• Species: Danio rerio
• Alignment Length: 700
• Identity: 149/700 - (21%)
• Similarity: 262/700 - (37%)
• Gaps: 185/700 - (26%)

  Fly   443 PSDSSSSGSSSAEHDQEPDPVQTTTMCSASSTTPLEPLHQLQLLLREKCGFNSQWPHAGSRTLAL 507
            |..:::...|:.|..:|..|.:.|                              |.......::.
Zfish    43 PMSAATGAISAVEKKREGYPERET------------------------------WTRQMDFIMSC 77

  Fly   508 IGCTLGVFNMCRFAVLTI-NFGGNFLLQFLLLSVIFGIPLLWLQMCLGAKIRAGPVSMWKISPIC 571
            :|..:|:.|:.||..|.. |.||.||:.::|...:.|||:.:|::.||..::||.:::|.|:|:.
Zfish    78 VGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLFIFLGGIPIFFLEIALGQFMKAGSINVWNIAPLF 142

  Fly   572 AGVGIALVMQQCFLALYSTVSLAWILVYLRDVFPTAARSGYRWQEMAFPY----------RYDAS 626
            .|:|.|.::...|...|..:.|||...|    |..:..:...|.....|:          :.|..
Zfish   143 KGLGYASMVIVFFCNTYYIMVLAWGFYY----FIKSFNATLPWSTCDNPWNTENCIEIFRQGDCK 203

  Fly   627 NAT------GNLT--------QTVAEYFNVVVLQRLHLANHPDASGIRFHVNDRQLAFYLALIWA 677
            |.|      ||||        ..:.|::...||......:.|.|      || .:|...|..:|.
Zfish   204 NGTIGNSTFGNLTCEELANGRSPIIEFWENKVLNISDGLDEPGA------VN-WELMLCLLAVWV 261

  Fly   678 AVFLILCKGLKSLGKLAYIIYTLPLVALAVVTAK----------FVYVVDPSRIQNIFAASDFDD 732
            .|:..:.||:||.||:.|...|.|.|.|.::..:          .:|.|.|.
Zfish   262 MVYFCVWKGVKSTGKIVYFTATFPYVVLIILLVRGVTLPGAYDGILYYVKPD------------- 313

  Fly   733 FLVNSNSWTAATQETFLTWGLLGASVIAITSRSHTNANKAALRRDAILLVLFT-LIGLGLMALLA 796
                              |..||.:.:.|               ||...:.|: .||||  ||.|
Zfish   314 ------------------WSKLGEAQVWI---------------DAGTQIFFSYAIGLG--ALTA 343

  Fly   797 LCCAQILWQHGYVYVPGSFE--NPDCYTSIYSL---QSNTNPYLLSYPRSLIPHYSSFIGETYRR 856
            |               ||:.  |.|||...:.|   .|.|:.:......|::...:|..|....:
Zfish   344 L---------------GSYNRFNNDCYKDAFVLALINSGTSFFAGFVVFSILGFMASEQGVDISK 393

  Fly   857 NRTMIHVESGFQALRFISEIFPAVLSLASDSISWVWAAVAFATFAGFGL-AQLCVMWKPISSALG 920
                 ..||| ..|.||:  :|..:|:.  .::.||||:.|......|| :|...:...::..|.
Zfish   394 -----VAESG-PGLAFIA--YPKAVSMM--PVAPVWAALFFIMLLLLGLDSQFVGVEGFVTGILD 448

  Fly   921 ----------NSTSSVLLSCVTGLLLSIPFATEMGISILYYVDFLLGGSWFIPIIWTAQIFGVFL 975
                      ....:|.:.|:...::.:...|:.|:.:....|:.....  :.::|  |.|...:
Zfish   449 LFPGKYYMRYQREIAVAICCLLCFIIDLSMVTQGGMYVFQLFDYYSASG--MTLLW--QAFWECV 509

  Fly   976 IRGRPYNGDDLVNDL-RLCGSMS-AFLALSWNVLLP---IGLITLSVVDYKASLSNQFYYWRGKS 1035
            :....|..|..::|: |:.|... .::...|:::.|   :|:....:::||....|..|
Zfish   510 VVAWVYGADRFMDDIARMIGYRPFPWMKWCWSIITPCVCMGIFLFHLLNYKPLTYNNVY------ 568

  Fly  1036 YFTYWSRKMGSLIQIGVLLVIPVTAIIQIYRYLAHGPPDILERIQLLYRP 1085
            .:.:|...:|..:.:..:|.|||:.:.:    |:.......||.:.|.:|
Zfish   569 VYPWWGEVIGWCLALSSMLCIPVSLVYK----LSGAKGTFKERWENLTKP 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	119/526 (23%)
slc6a8	NP_001314797.1	SLC6sbd_CT1	64..652	CDD:271397	143/678 (21%)