DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bdg and slc6a16a

DIOPT Version :9

Sequence 1:	NP_611064.2	Gene:	bdg / 36747	FlyBaseID:	FBgn0034049	Length:	1331	Species:	Drosophila melanogaster
Sequence 2:	XP_021327051.1	Gene:	slc6a16a / 555229	ZFINID:	ZDB-GENE-061009-43	Length:	693	Species:	Danio rerio

Alignment Length:	763	Identity:	172/763 - (22%)
Similarity:	280/763 - (36%)	Gaps:	214/763 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   442 LPSDSSSS-----------------GSSSAEHDQEPDPVQTTTMCSASSTTPLEPLHQLQLLLRE 489
            ||||.:.|                 ||:.|:..::..|.
Zfish     6 LPSDENGSVLTESRSDMALVSADDEGSAGADGQEDDRPA-------------------------- 44

  Fly   490 KCGFNSQWPHAGSRTLALIGCTLGVFNMCRFAVLT-INFGGNFLLQFLLLSVIFGIPLLWLQMCL 553
                   |.......||.:|.::|:.|:.||..|. .|.||.|:|.:::|.:|.|:||.::::..
Zfish    45 -------WDSKLQYVLAQVGFSVGLGNVWRFPYLCHQNGGGAFMLLYVMLLLIIGVPLFFMELAA 102

  Fly   554 GAKIRAGPVSMWK-ISPICAGVGIALVMQQCFLALYSTVSLAWILVYLRDVFPTAARSGYRWQEM 617
            |..||.|.:.:|| |||..||:|.:..|...|:|||..|.:||.|.|:.:.|           :.
Zfish   103 GQSIRQGSIGVWKHISPRLAGIGYSSCMVCFFVALYYNVIIAWSLFYMGNSF-----------QY 156

  Fly   618 AFPYRYDASNATGNLTQTVAE--------YFNVVVLQRLHLANHPDASGIRFHVNDRQLAFYLAL 674
            ..|:.....:...|  |||.|        ||  ...:.|.:::..|.||   ..|.......||
Zfish   157 PLPWEQCPVDMISN--QTVKECAASSPTSYF--WFRKALDISDSIDQSG---EFNPIMTGCLLA- 213

  Fly   675 IWAAVFLILCKGLKSLGKLAYIIYTLPLVAL------------AVVTAKFVY---VVDPSRIQNI 724
            .||.|.|.:.||:||..|:.|.....|...|            |:...|:::   |.....:|
Zfish   214 AWAIVCLAMIKGIKSSAKVMYFSSVFPYAVLICFLIRGLMLDGAIDGIKYMFYPKVEIWGEVQ-- 276

  Fly   725 FAASDFDDFLVNSNSWTAATQETFLTWGLLGASVIAITSRS--HTNANKAALRRDAIL------- 780
                          .|..|..:.|...||...||||.:|.:  |.|.:     ||||:
Zfish   277 --------------VWRQAATQVFFALGLGYGSVIAYSSYNPIHNNCH-----RDAIMVSGINFM 322

  Fly   781 ------LVLFTLIGLGLMALLALCCAQILWQHGYVYVPGSFENPDCYTSIYSLQSNTNPYLLSYP 839
                  ||:|.::|.....:...|.|..:.:...:...||.::   :..::::....:..|..|
Zfish   323 TSVLASLVVFVVLGFRAKNIALDCVATNVARMAEMAQTGSSQH---WRPLFNMSDPKSVVLQDY- 383

  Fly   840 RSLIPHYSSFIGETYRRNRTMIHVESGFQ--ALRFIS-----EIFPAVLSLASDSISWVWAAVAF 897
            |.....|.|.:|...........:..|.:  .|.||:     .:|||         |..|:.:.|
Zfish   384 RQWYSSYGSLLGSNITDCDLEREMSKGVEGTGLAFIAFTEAMALFPA---------SPFWSTLFF 439

  Fly   898 ATFAGFGLAQLCVMWKPISSAL--------GNSTSSVLLSCVTGLLLSIPFATEMGISILYYVDF 954
            ......||:.:....:.|.:.|        .:.|...:.||:.|.|:.:.|....|   .|:|..
Zfish   440 LMLLNLGLSTMFGTMQGILTPLMDNFRVLGRHKTMLTVCSCILGFLIGLLFTQRSG---NYFVTM 501

  Fly   955 LLGGSWFIPII--------WTAQIFGV--FLIRGRPYNGDDLVNDLRLCGSMSAFLALSWNVLLP 1009
            ....|..:|:|        ..|.|:|.  ||        ||:  ::.|...........|..:..
Zfish   502 FDDYSATLPLIIVVIFETVSVAWIYGADRFL--------DDV--EVMLHWRPPVVYRYLWKYVCL 556

  Fly  1010 IGLITLSVVDYKASLSNQFYYWRGKSYFTYWSRKMGS----------LIQIGVLLVI---PVTAI 1061
            :|::.|    ..|||....:   .:..:|.|:...||          |:.:.:|:::   || .|
Zfish   557 LGMVGL----LAASLLRMVF---KRPTYTAWNHTTGSEASLEYPGWALVVLSMLIIVASLPV-PI 613

  Fly  1062 IQIYRYLAHGPPDILERIQLLYRPPEEGE--EPRRPSARQTASQSRRN 1107
            ..:..:|..|          |..|.||||  .||...::.::::...|
Zfish   614 GYLLSFLRGG----------LNLPVEEGEIQPPRELYSKCSSAEPEPN 651

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	132/539 (24%)
slc6a16a	XP_021327051.1	SLC6sbd-B0AT-like	42..617	CDD:271364	153/681 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900