DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bdg and RGD1562492

DIOPT Version :9

Sequence 1:	NP_611064.2	Gene:	bdg / 36747	FlyBaseID:	FBgn0034049	Length:	1331	Species:	Drosophila melanogaster
Sequence 2:	NP_001102616.1	Gene:	RGD1562492 / 499151	RGDID:	1562492	Length:	743	Species:	Rattus norvegicus

Alignment Length:	810	Identity:	159/810 - (19%)
Similarity:	285/810 - (35%)	Gaps:	257/810 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   453 SAEHDQEP---DPVQTTTMCSASSTTPLEPLHQLQLLLREKCGFNSQWPHAGSRT---------- 504
            |.|...||   :|.:.....|..||.|.                :..|   |.:|
  Rat     4 SFEEVPEPKKEEPTEEEPTASKKSTDPT----------------SLSW---GFKTREVRITKISS 49

  Fly   505 ----------LALIGCTLGVFNMCRFAVLT-INFGGNFLLQFLLLSVIFGIPLLWLQMCLGAKIR 558
                      |.|:..::|:.:..||..|. .|.||:|||.:|:|.::.||||::::|.:|..:|
  Rat    50 HFQAKKTENILILVAFSIGLGSTWRFPYLCHQNGGGSFLLMYLILLLLLGIPLMYMEMVIGQWLR 114

  Fly   559 AGPVSMWK-ISPICAGVGIALVMQQCFLALYSTVSLAWILVYLRDVF--PTAARSGYRWQEMAFP 620
            ...:..|| :.|..:|||.:.::....:.||::..::|.|.||...|  ||.      |:.....
  Rat   115 VDNIRAWKHLVPWLSGVGYSSMLACALVILYNSALVSWSLFYLGQSFDYPTP------WENCPLV 173

  Fly   621 YRYDASNATGNLTQTVAEYFNVVVLQRLHLANHPDASGIRFHVNDRQLAFY-------------- 671
            ..:..|:.:...|:....::...||:    |:.....||...|.:..|..:
  Rat   174 KNFSTSDISCLRTEPHQFFWYHTVLR----ASDQIEEGIEVLVLNVTLCLFATWFFLYITMVTRI 234

  Fly   672 ----LALIWAAVF---LILC--------KGLK-SLGKL------------------AYIIYTLPL 702
                |.:|::.:|   |:.|        ||:: ||.:|                  .:::|:|.|
  Rat   235 KISVLMMIFSILFPNVLLFCFFTHIFFVKGVRDSLKRLVTTELSILASLDAWRQAGGHVLYSLGL 299

  Fly   703 VALAVVTAKFVYVVDPSRIQNIFAASDFDDFLVNSNSWTAATQETFLTWGLLGASVIAITSRSHT 767
            ....::|                    |..:....        |.::.|....|.|..:||...:
  Rat   300 GMGTIIT--------------------FSSYQTRG--------ENYIKWASFVAMVNLMTSLLSS 336

  Fly   768 NANKAALRRDAILLVLFTLIGL---------------GLMALLAL-CCAQILWQHGYVYVPGSFE 816
            :             |:|.::|.               .|::|:|. ...|:.|....:......|
  Rat   337 S-------------VIFLMLGFWIENSGTPCVESNVSNLLSLIANGVLPQVAWPPKDIIHRSPLE 388

  Fly   817 NPDCYTSIYSLQSNTNPYLLSYPRSLIPHYSSFIGETYRRNRTMIHVESGFQALRFISEIFPAVL 881
            ..|.   |..|..|.        |:.:.|::.......::.:.|......:.|......:||.
  Rat   389 YLDW---ISQLPKNI--------RNEVAHFTLPCSILVQKEKFMEGPGLAYVAFSQAITLFPG-- 440

  Fly   882 SLASDSISWVWAAVAFATFAGFGLAQLCVMWKPISSALGNSTSSV--------LLSCVTGLLLSI 938
                   |..||.:.|.:....||..:..:.:.|:.:|..|.|::        ::.|:.|.|.|:
  Rat   441 -------SSFWAIIFFMSLVIMGLGTMTTLVEGIALSLQKSISTLEKHPKLVPVIICLGGFLGSL 498

  Fly   939 PFATEMGISILYYVDFLLGGSWFIPIIW----------TAQIFGVFLIRGRPYNGDDLVNDL-RL 992
            .|::..|..:::..|     ...:|::.          .|.::|:...|.      ::...| ||
  Rat   499 VFSSRPGSYVVFLFD-----DHLVPMVLIMIVAFQNLSLAWVYGIKRFRA------EMFGQLGRL 552

  Fly   993 CGSMSAFLALSWN-VLLPIGLITLSVVDYKASLSNQFYYWRGKSYFTYWSRKMG-------SLIQ 1049
            ..:...||   |: |.||..|:.|::  |..:|    |:....||.: |:..|.       ..|.
  Rat   553 VWAPFTFL---WSYVTLPTLLVLLTI--YFLNL----YFSESLSYVS-WNNSMSQEVKQPYQRIA 607

  Fly  1050 IGVLLVIPVTAIIQIYRY-LAH----GPPDILERIQ-------LLYRPPEEGEEPRRPSARQT-A 1101
            :|.:..:.|.|::.|..| |.|    ....|.|.|:       .:..|....:.|..|..:.| .
  Rat   608 LGWVTFLSVLALLPIPMYPLQHWWYLDDQIICETIEKPLSSKKTVTVPKRVTQWPVHPMRKLTLR 672

  Fly  1102 SQSRRNALGQTTEGGQHDAQNDAPPKYTPP 1131
            :|.:..||.|:.               |||
  Rat   673 NQEKSKALFQSK---------------TPP 687

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	108/580 (19%)
RGD1562492	NP_001102616.1	SLC5-6-like_sbd	50..621	CDD:382020	129/662 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900