Protein Alignment bdg and SerT

DIOPT Version :10

• Sequence 1: NP_611064.2
• Gene: bdg / 36747
• FlyBaseID: FBgn0034049
• Length: 1331
• Species: Drosophila melanogaster
• Sequence 2: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Alignment Length: 742
• Identity: 158/742 - (21%)
• Similarity: 289/742 - (38%)
• Gaps: 147/742 - (19%)

  Fly   429 SSARSSRMPSPVSLPSDSSSSGSSSAEHDQEPDPVQTTTMCSASSTTPLEPL-----HQLQLLLR 488
            ::.||:  |:|.|...:|.::...|.|.|.:    .||   .|..|.||.|.     ..|.:.:.
  Fly    15 TTGRSN--PAPWSDDKESPNNEDDSNEDDGD----HTT---PAKVTDPLAPKLANNERILVVSVT 70

  Fly   489 EKCGFNSQWPHAGSRTLALIGCTLGVFNMCRFAVLTI-NFGGNFLLQFLLLSVIFGIPLLWLQMC 552
            |:.  ...|.......||:||..:.:.|:.||..:.. |.||.||:.:.|..:..|:||.::::.
  Fly    71 ERT--RETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELA 133

  Fly   553 LGAKIRAGPVSMWK-ISPICAGVGIALVMQQCFLALYSTVSLAWILVYLRDVFPTAARSGYRWQE 616
            ||...|.|.:|:|| |.|...|||.|:.:...::.:|....:.|.:.||...|    .|...|..
  Fly   134 LGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASF----TSKLPWTS 194

  Fly   617 MAFPYRYD------ASNATGNLTQTVAEYFNVVVLQRLHLANHPDASG-IRFHVNDRQLAFYLAL 674
            ...|:..:      :.|.|...|....|:|...||:. :..|..|..| ::     ..||..:..
  Fly   195 CDNPWNTENCMQVTSENFTELATSPAKEFFERKVLES-YKGNGLDFMGPVK-----PTLALCVFG 253

  Fly   675 IWAAVFLILCKGLKSLGKLAYIIYTLPLVALAVVTAKFVYVVDPSRIQNIFAASDFDDFLVNSNS 739
            ::..|:..|.||::|.||:.::....|.|.|.::..:.|.:.........:...::.. |.||..
  Fly   254 VFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHK-LKNSKV 317

  Fly   740 WTAATQETFLTWGLLGASVIAITSRSHTNANKAALRRDAILLVLFTLIGLGLMALLALCCAQILW 804
            |..|..:.|.:.|....:::|::|.:..|.|   ..|||::.
  Fly   318 WIDAASQIFFSLGPGFGTLLALSSYNKFNNN---CYRDALIT----------------------- 356

  Fly   805 QHGYVYVPGSFENPDCYTSIYSLQSNTNPYLLSYPRSLIPHYSSFIGETYRRNRTMIHVESGFQA 869
                       .:.:|.||          :|..:....:..|.:::      .:|.|. :.|.:.
  Fly   357 -----------SSINCLTS----------FLAGFVIFSVLGYMAYV------QKTSID-KVGLEG 393

  Fly   870 LRFISEIFPAVLSLASDSISWVWAAVAF---------ATFAGFGLAQLCVMWKPISSALGNSTS- 924
            ...:..::|..::..|.|:  .|:.:.|         :||.|.. |.:..:.......:|....
  Fly   394 PGLVFIVYPEAIATMSGSV--FWSIIFFLMLITLGLDSTFGGLE-AMITALCDEYPRVIGRRREL 455

  Fly   925 SVLLSCVTGLLLSIPFATEMGISILYYVDFLLGGSWFIPIIWTAQIFGVFLIRGRPYNGDDLVND 989
            .|||......|.::|..|..|:.::.::: :.|....|..:...:..|||..    |..|...:|
  Fly   456 FVLLLLAFIFLCALPTMTYGGVVLVNFLN-VYGPGLAILFVVFVEAAGVFWF----YGVDRFSSD 515

  Fly   990 L-RLCGSM-SAFLALSWNVLLPIGLITL---SVVDYKASLSNQFYYWRGKSYFTYWSRKMGSLIQ 1049
            : ::.||. ..|..:.|..:.|:.|:|:   |::.||..|..::||       ..||.::|..:.
  Fly   516 VEQMLGSKPGLFWRICWTYISPVFLLTIFIFSIMGYKEMLGEEYYY-------PDWSYQVGWAVT 573

  Fly  1050 IGVLLVIPVTAIIQIYRYLAHGPPDILERIQLLYRPP---------EEGEEPRRPSARQTAS--- 1102
            ...:|.||:..   ||::.........:|:|..::|.         ::|.......|:...:
  Fly   574 CSSVLCIPMYI---IYKFFFASKGGCRQRLQESFQPEDNCGSVVPGQQGTSVXHDHAQVHVNIRT 635

  Fly  1103 ------------QSRRNALGQTTEGGQ 1117
                        .|..|:|..||.|.:
  Fly   636 SCTSIKIYNLNCSSNSNSLSPTTSGAE 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	104/493 (21%)
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	131/615 (21%)