Protein Alignment bdg and SLC6A19

DIOPT Version :9

• Sequence 1: NP_611064.2
• Gene: bdg / 36747
• FlyBaseID: FBgn0034049
• Length: 1331
• Species: Drosophila melanogaster
• Sequence 2: NP_001003841.1
• Gene: SLC6A19 / 340024
• HGNCID: 27960
• Length: 634
• Species: Homo sapiens
• Alignment Length: 669
• Identity: 138/669 - (20%)
• Similarity: 265/669 - (39%)
• Gaps: 145/669 - (21%)

  Fly   480 LHQLQLLLREKCGFNSQWPHAGSRTLALIGCTLGVFNMCRFAVLTINFGGN-FLLQFLLLSVIFG 543
            |.:|:.:.:|:.....:|.:.....|..:|..:|:.|:.||..|..:.||. |::.||:|.|:.|
Human    18 LAELETIEQEEASSRPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEG 82

  Fly   544 IPLLWLQMCLGAKIRAGPVSMW-KISPICAGVGIALVMQQCFLALYSTVSLAWILVYLRDVFPTA 607
            ||||:|:..:|.::|.|.:.:| .|.|...|:|:|.::....:.||....::||:.||.:.|
Human    83 IPLLYLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSF--- 144

  Fly   608 ARSGYRWQEMAFPYRYDASNATGNLTQ----TVAEYFNVVVLQRLHLANH-PDASGIRFHVNDRQ 667
             :....|.:...     ..|.||.:.:    :..:||  ...:.|:::.. .|:..|::     .
Human   145 -QEPLPWSDCPL-----NENQTGYVDECARSSPVDYF--WYRETLNISTSISDSGSIQW-----W 196

  Fly   668 LAFYLALIWAAVFLILCKGLKSLGKLAYIIYTLPLVALAV----------VTAKFVYVVDPSRIQ 722
            :...||..|:.:::...:|:::.||..||..|||.|.|.:          .|...|::..|:..:
Human   197 MLLCLACAWSVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNVTE 261

  Fly   723 NIFAASDFDDFLVNSNSWTAATQETFLTWGLLGASVIAITSRS--HTNANKAALRRDAIL----- 780
                       |...::|..|..:.|.::.|....:|:.:|.:  |.|..|     |:::
Human   262 -----------LAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCEK-----DSVIVSIIN 310

  Fly   781 --------LVLFTLIGLGLMALLALCCAQILWQHGYVYVPGSFENPD---CYTSIYSLQSNTNPY 834
                    :|::::||.........|     :....:.:...|:.|:   ...:...:|...|
Human   311 GFTSVYVAIVVYSVIGFRATQRYDDC-----FSTNILTLINGFDLPEGNVTQENFVDMQQRCN-- 368

  Fly   835 LLSYPRSLIPHYSSFIGETYRRNRTMIHVESGFQALRFISEIFPAVLSLASDSISWVWAAVAFAT 899
             .|.|.:    |:..:.:|...|..:.....| ..|.||  :|..  ::....:|.:|:.:.|..
Human   369 -ASDPAA----YAQLVFQTCDINAFLSEAVEG-TGLAFI--VFTE--AITKMPLSPLWSVLFFIM 423

  Fly   900 FAGFGLAQLCVMWKPISSALGNSTSSVL-------------------LSCVTGLLLSIPFATEMG 945
            ....||          ||..||....|:                   |.|:...|:...|....|
Human   424 LFCLGL----------SSMFGNMEGVVVPLQDLRVIPPKWPKEVLTGLICLGTFLIGFIFTLNSG 478

  Fly   946 ISILYYVDFLLGGSWFIPIIWTA--QIFGVFLIRGRPYNGDDLVNDLRLCGSMSAFLALSWNVLL 1008
               .|::..|...:..||::..|  ::|.|..:.|......|:  :..:....:.|..::|.|:.
Human   479 ---QYWLSLLDSYAGSIPLLIIAFCEMFSVVYVYGVDRFNKDI--EFMIGHKPNIFWQVTWRVVS 538

  Fly  1009 PIGLITLSVVDYKASLSNQFYYWRGKSYFTYW---------SRKMG--------SLIQIGV-LLV 1055
            |:.::.:.:..:...:|.:..|       :.|         |:|:.        .:|..|| .|.
Human   539 PLLMLIIFLFFFVVEVSQELTY-------SIWDPGYEEFPKSQKISYPNWVYVVVVIVAGVPSLT 596

  Fly  1056 IPVTAIIQIYRYLAHGPPD 1074
            ||..||.::.|.....|.|
Human   597 IPGYAIYKLIRNHCQKPGD 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	112/530 (21%)
SLC6A19	NP_001003841.1	SLC5-6-like_sbd	32..612	CDD:294310	133/650 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900