DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bdg and Slc6a16

DIOPT Version :9

Sequence 1:	NP_611064.2	Gene:	bdg / 36747	FlyBaseID:	FBgn0034049	Length:	1331	Species:	Drosophila melanogaster
Sequence 2:	XP_038949993.1	Gene:	Slc6a16 / 292902	RGDID:	1561338	Length:	850	Species:	Rattus norvegicus

Alignment Length:	825	Identity:	175/825 - (21%)
Similarity:	300/825 - (36%)	Gaps:	220/825 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   343 VAPTVGSQMLTEAHIFDNLLQTNARASSEEPRPRQYGRRLEGPPTPVRPLILAQSRPQSAPTRVQ 407
            |||.:.|...:|    |......:|||:.: ||.:..              |.::...|....|.
  Rat    90 VAPDMRSSKESE----DAFFLAKSRASASD-RPEESS--------------LVKTSGSSLDKNVS 135

  Fly   408 MREPQLQDTPTHPIM---------STC-----SELSSARSSRMPSPVSLPSDSSSSGS------S 452
            :...:|.:..::.::         ||.     :::|.:|.::..:..:|..::.:.|:      |
  Rat   136 IETTKLSEMDSNLLVWEDGTLATWSTSAWIAQAQVSESRVAKAQAWETLALEAQARGALQFNKPS 200

  Fly   453 SAEHDQEPDPVQTTTMCSASSTTPLEPLHQLQLLLREKCGFNSQ-------WPHAGSRTLALIGC 510
            :.|:..|..|.|         .:|:|        |.:....||.       |.......|||:|.
  Rat   201 TTEYSMETTPKQ---------ESPIE--------LNKTSKENSNVFPPWLLWSSKAEYILALMGY 248

  Fly   511 TLGVFNMCRFAVLTINFGG-NFLLQFLLLSVIFGIPLLWLQMCLGAKIRAGPVSMWK-ISPICAG 573
            .:....:.||....::.|. :|.:.:||:....|||||:|:|.:|.:.:...:.:|| :||...|
  Rat   249 LVMPSGLLRFVTCWVHKGSWSFFIAYLLMLFGLGIPLLFLEMAVGQRAQQSSIDLWKTLSPWFGG 313

  Fly   574 VGIALVMQQCFLALYSTVSLAWILVYLRDVFPTAARSGYRWQEMAFPYRYDASNATGNLTQTVAE 638
            :|.::||.......|..|..:|||.|:..:|....    .|...  |.:.::|:......|..:
  Rat   314 LGYSMVMVCLITNTYLNVFNSWILFYMSHIFHFVV----PWDRC--PLQKNSSDFDPECEQATS- 371

  Fly   639 YFNVVVLQRLHLANHPDASGIRFHVNDRQLAFYLALIWAAVFLILCKGLKSLGKLAYIIYTLP-- 701
            |......|.|..::..:..|    .....||.:|.|.|..:.:.:..|:|||||:..::..:|
  Rat   372 YTYFWYRQTLKASDSIEDGG----QPSFNLAMFLFLAWCLICVFMVNGIKSLGKVLCVLLQVPYF 432

  Fly   702 -LVALAVVT----------AKFVYVVDPSRIQNIFAASDFDDFLVNSNSWTAATQETFLTWGLLG 755
             ::...|.|          ..::.:::.:||.::             ..|..|..:.....||..
  Rat   433 IIICFLVRTLSMGNGIGYGLNYLLILEVARISDL-------------TMWCQAGIQVLFDIGLGF 484

  Fly   756 ASVIAITSRSHTNANKAALRRDAILLVLFTLIG-----------LGLMALLAL--CCA----QIL 803
            ..||:::  ||.:.....| :||.|:.||.::.           ||..|.:..  ||.    ::|
  Rat   485 GPVISLS--SHMSDFNNCL-KDAFLMGLFKIVTLLITTPFFLSILGFWATITTHHCCKKNTNKLL 546

  Fly   804 WQHGYVYVPGSFENPDCY---TSIYSLQSNTNPYLLSYPRSLIPHYSSFIGETYRRNRTMIHVES 865
            .......:|...|.||..   .|||      |.:|.|.|..|.....|.:.|        .:::.
  Rat   547 MLIAQGILPPEVEPPDLNDDPISIY------NSWLNSLPPPLRSAVLSMVPE--------CNIQK 597

  Fly   866 GFQAL----RFISEIFPAVLSLASDSISWVWAAVAFATFAGFGL-AQLCVMWKPISSALGNSTSS 925
            .|..:    ||:..||..|:||...|.  .|..:.|....|.|| ..|..|       |||
  Rat   598 QFMRIEDSPRFLFLIFTEVISLLPGSA--FWTVLFFLALLGLGLCTNLMYM-------LGN---- 649

  Fly   926 VLLSCVTGLLLSIPFATE------MGISI--------------LYYVDFLLGGSWF-IPII---- 965
                 :..|..:.||...      :|:|:              :||.. ||...|. :|||
  Rat   650 -----ILTLQDTFPFCRRQPRLLTVGVSMTTFLCGLIFIQPSGIYYFS-LLSEYWVAVPIITIIL 708

  Fly   966 -------WTAQIFGVFLIRGRPYNGDDLVNDLRLCGSMSAFLALSW-----NVLLPIGLITLSVV 1018
                   |.             |.....:.|:....|...|...||     :.::.:||: |.:.
  Rat   709 CETLAVAWA-------------YGAKRFLADMMALLSRPIFPGCSWLWRYVSPVVLLGLL-LFIC 759

  Fly  1019 DYKASLSNQFYYWRGKS------YFTYWSRKMGSLIQIGVLLVIP 1057
            .|.......:..|...:      ||..||..:.:.:...||:.||
  Rat   760 IYLVQGPLVYMAWDSSTSKEVVRYFPMWSLMLIAGLSAVVLMPIP 804

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	124/546 (23%)
Slc6a16	XP_038949993.1	SLC6sbd_NTT5	232..802	CDD:271392	142/643 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000