Protein Alignment bdg and Slc6a3

DIOPT Version :9

• Sequence 1: NP_611064.2
• Gene: bdg / 36747
• FlyBaseID: FBgn0034049
• Length: 1331
• Species: Drosophila melanogaster
• Sequence 2: NP_036826.1
• Gene: Slc6a3 / 24898
• RGDID: 3715
• Length: 619
• Species: Rattus norvegicus
• Alignment Length: 731
• Identity: 176/731 - (24%)
• Similarity: 285/731 - (38%)
• Gaps: 198/731 - (27%)

  Fly   436 MPSPVSLPSDSSSSGSSSAE--HDQEPDPVQTTTMCSASSTTPLEPLHQLQLLLREKCGFNSQWP 498
            |.|.|:...:|::.|....|  ..:|.:.||.|     :||....|...::...||      .|.
  Rat    11 MSSVVAPAKESNAVGPREVELILVKEQNGVQLT-----NSTLINPPQTPVEAQERE------TWS 64

  Fly   499 HAGSRTLALIGCTLGVFNMCRFAVLTI-NFGGNFLLQFLLLSVIFGIPLLWLQMCLGAKIRAGPV 562
            ......|::||..:.:.|:.||..|.. |.||.||:.:||..||.|:||.::::.||...|.|..
  Rat    65 KKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAA 129

  Fly   563 SMWKISPICAGVGIALVMQQCFLALYSTVSLAWILVYLRDVFPTAARSGYRWQEMAFPYRY---- 623
            .:|||.|:..|||..:::...::..:..|.:||.|.|....|           .|..|:.:
  Rat   130 GVWKICPVLKGVGFTVILISFYVGFFYNVIIAWALHYFFSSF-----------TMDLPWIHCNNT 183

  Fly   624 ---------DASNATGNL-------TQTVAEYFNVVVLQRLHLANHPDASG-IRFHVNDRQLAFY 671
                     .|||::..|       |...||||...|| .||.:...|..| .|:     ||...
  Rat   184 WNSPNCSDAHASNSSDGLGLNDTFGTTPAAEYFERGVL-HLHQSRGIDDLGPPRW-----QLTAC 242

  Fly   672 LALIWAAVFLILCKGLKSLGKLAYIIYTLPLVALAVVTAKFVYVVDPSRIQNIFAASDFDDF-LV 735
            |.|:...::..|.||:|:.||:.:|..|:|.|.|..:..:.|.:  |..:..|.|....|.: |.
  Rat   243 LVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTL--PGAMDGIRAYLSVDFYRLC 305

  Fly   736 NSNSW-TAATQETFLTWGLLGASVIAITSRSHTNANKAALRRDAILLVLFTLIGLGLMALLALCC 799
            .::.| .||||                                    |.|:| |:|...|:|.
  Rat   306 EASVWIDAATQ------------------------------------VCFSL-GVGFGVLIAF-- 331

  Fly   800 AQILWQHGYVYVPGSFENPDCY------TSIYSLQSNTNPYLLSYPRSLIPHYSSFIGETYRRNR 858
                  ..|    ..|.| :||      |||.||.|.::.:::          .||:|...:::.
  Rat   332 ------SSY----NKFTN-NCYRDAIITTSINSLTSFSSGFVV----------FSFLGYMAQKHN 375

  Fly   859 TMIH-VESGFQALRFISEIFPAVLSLASDSISWVWAAVAFATFAGFGLAQLCVMWKPISSALGNS 922
            ..|. |.:....|.||  |:|.  ::|:..:|..||||.|......|          |.||:|.
  Rat   376 VPIRDVATDGPGLIFI--IYPE--AIATLPLSSAWAAVFFLMLLTLG----------IDSAMGG- 425

  Fly   923 TSSVLLSCVTGL-----------------------LLSIPFATEMGISILYYVDFLLGGSWFIPI 964
                :.|.:|||                       |||:...|..||.:...:|....|
  Rat   426 ----MESVITGLVDEFQLLHRHRELFTLGIVLATFLLSLFCVTNGGIYVFTLLDHFAAG------ 480

  Fly   965 IWTAQIFGVFL-------IRGRPYNGDDLVNDLRLCGSM-SAFLALSWNVLLP---IGLITLSVV 1018
              |:.:|||.:       ..|.....||:   .::.|.. :.:..|.|.::.|   :.::.:|:|
  Rat   481 --TSILFGVLIEAIGVAWFYGVQQFSDDI---KQMTGQRPNLYWRLCWKLVSPCFLLYVVVVSIV 540

  Fly  1019 DYKASLSNQFYYWRGKSYFTYWSRKMGSLIQIGVLLVIPVTAIIQIYRYLAHGPPDILERIQLLY 1083
            .::..     :|  |...|..|:..:|.:|....:.::|:.|   .|::.:. |....|::....
  Rat   541 TFRPP-----HY--GAYIFPDWANALGWIIATSSMAMVPIYA---TYKFCSL-PGSFREKLAYAI 594

  Fly  1084 RPPEEGEEPRRPSARQ 1099
            .|.::.:...|...||
  Rat   595 TPEKDHQLVDRGEVRQ 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	136/535 (25%)
Slc6a3	NP_036826.1	SLC6sbd_DAT1	60..613	CDD:212083	163/677 (24%)
		Interaction with TGFB1I1. /evidence=ECO:0000250	560..589		6/32 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900