Protein Alignment bdg and Slc6a1

DIOPT Version :10

• Sequence 1: NP_611064.2
• Gene: bdg / 36747
• FlyBaseID: FBgn0034049
• Length: 1331
• Species: Drosophila melanogaster
• Sequence 2: NP_848818.1
• Gene: Slc6a1 / 232333
• MGIID: 95627
• Length: 599
• Species: Mus musculus
• Alignment Length: 722
• Identity: 168/722 - (23%)
• Similarity: 291/722 - (40%)
• Gaps: 187/722 - (25%)

  Fly   442 LPSDSS--SSGSSSAEHDQEPDPVQTTTMCSASSTTPLEPLHQLQLLLREKCG---FNSQWPHAG 501
            :.:|:|  :.|..|.|..:.|          .:|..|    ..|.:.:::|.|   ....|....
Mouse     1 MATDNSKVADGQISTEVSEAP----------VASDKP----KTLVVKVQKKAGDLPDRDTWKGRF 51

  Fly   502 SRTLALIGCTLGVFNMCRFAVLT-INFGGNFLLQFLLLSVIFGIPLLWLQMCLGAKIRAGPVSMW 565
            ...::.:|..:|:.|:.||..|. .|.||.||:.:.|..:..|:||..|:..||.....|.:.:|
Mouse    52 DFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVW 116

  Fly   566 KISPICAGVGIALVMQQCFLALYSTVSLAWILVYLRDVFPTAARSGYRWQEMAFPYRYDA--SN- 627
            |::|:..|||:|..:...:|.:|..|.::|.:.||.:.|.|.    ..|::...|:..|.  ||
Mouse   117 KLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTT----LPWKQCDNPWNTDRCFSNY 177

  Fly   628 ---ATGNLTQTVAEYFNVVVLQRLH-LANHPDASG-IRFHVNDRQLAFYLALIWAAVFLILCKGL 687
               .|.|:|..|.|::.    :.:| :.:..|..| ||:     .||..||:.|..|:..:.||:
Mouse   178 SLVNTTNMTSAVVEFWE----RNMHQMTDGLDKPGQIRW-----PLAITLAIAWVLVYFCIWKGV 233

  Fly   688 KSLGKLAYIIYTLPLVALAVVTAKFVYVVDPSRIQNI--FAASDFDDFLVNSNSWTAATQETFLT 750
            ...||:.|...|.|.:.|.::.  |..|..|...:.|  :...:|.. |.:|..|..|..:.|.:
Mouse   234 GWTGKVVYFSATYPYIMLIILF--FRGVTLPGAKEGILFYITPNFRK-LSDSEVWLDAATQIFFS 295

  Fly   751 WGLLGASVIAITSRS--HTNANKAALRRDAILLVLFTLIGLGLMALLALCCAQILWQHGYVYVPG 813
            :||...|:||:.|.:  |.|     :.||:|:                :||..
Mouse   296 YGLGLGSLIALGSYNSFHNN-----VYRDSII----------------VCCIN------------ 327

  Fly   814 SFENPDCYTSIYSLQSNTNPYLLSYPRSLIPHYSSFIGETYRRNRTMIHVESGFQALRFISEIFP 878
                 .| ||:::      .:::......:.|.:         .|::..|.:....|.|::  :|
Mouse   328 -----SC-TSMFA------GFVIFSIVGFMAHVT---------KRSIADVAASGPGLAFLA--YP 369

  Fly   879 -AVLSLASDSISWVWAAVAFATFAGFGL-AQLCVMWKPISSALGNSTSSVLLS---------CVT 932
             ||..|   .||.:||.:.|:.....|: :|.|.: :...:||.:....:|.:         |:.
Mouse   370 EAVTQL---PISPLWAILFFSMLLMLGIDSQFCTV-EGFITALVDEYPRLLRNRRELFIAAVCIV 430

  Fly   933 GLLLSIPFATEMGI--------------SILYYVDF-LLGGSWFIPIIWTAQIFGVFLIRGRPYN 982
            ..|:.:...|:.||              |:|:.|.| .:..|||         :||    .|.|:
Mouse   431 SYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWF---------YGV----NRFYD 482

  Fly   983 GDDLVNDLRLCGSMSA-FLALSWNVLLPI---GLITLSVVDYKASLSNQFYYWRGKSYFTYWSRK 1043
                 |...:.||... :..|.|:...||   |:...|.|....       ...|...|..|.:.
Mouse   483 -----NIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFSAVQMTP-------LTMGSYVFPKWGQG 535

  Fly  1044 MGSLIQIGVLLVIPVTAIIQIYRYLAH------GPPDILERIQLLYRP------PEEGEEPRRPS 1096
            :|.|:.:..:::||        .|:|:      |  .:.:|:|::.:|      ||.|  |.:|.
Mouse   536 VGWLMALSSMVLIP--------GYMAYMFLTLKG--SLKQRLQVMIQPSEDIVRPENG--PEQPQ 588

  Fly  1097 ARQTASQ 1103
            |..:||:
Mouse   589 AGSSASK 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	123/513 (24%)
Slc6a1	NP_848818.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		6/31 (19%)
		SLC6sbd_GAT1	2..599	CDD:212075	168/721 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	577..599		8/21 (38%)
		PDZ-binding	597..599