DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bdg and F56F4.3

DIOPT Version :9

Sequence 1:	NP_611064.2	Gene:	bdg / 36747	FlyBaseID:	FBgn0034049	Length:	1331	Species:	Drosophila melanogaster
Sequence 2:	NP_491770.3	Gene:	F56F4.3 / 186398	WormBaseID:	WBGene00018980	Length:	701	Species:	Caenorhabditis elegans

Alignment Length:	776	Identity:	145/776 - (18%)
Similarity:	273/776 - (35%)	Gaps:	223/776 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   432 RSSRMPSPVSLPSDSSSSGSSSAEHDQEPDPVQTTTMCSASSTTPLEPLH-QLQLLLREKCGFNS 495
            :..||.|..|  |..:..|....::|:|       ...|.:....|.|.. :.:.|.:|....|.
Worm    48 KKKRMDSTES--SSENPDGIEKFDNDEE-------LAISPTGNPNLNPSKIEAEELEQEIGSRNI 103

  Fly   496 QWPHAGSRTLALIGCTLGVFNMCRFAVLTINFGG-NFLLQFLLLSVIFGIPLLWLQMCLGAKIRA 559
            ..|....:...|:.|...:.|...|.....|.|| .|.:.:.::..:.|:|:...::.| |:..:
Worm   104 SRPSTYRQLSLLLSCVTLLKNNMVFIECFFNHGGVYFFVPYFIILFVLGVPMAIFELSL-AQFSS 167

  Fly   560 GPVS--MWKISPICAGVGIALVMQQCFLALYSTVSLAW---ILVYLRDVFPTAARSGYRW----- 614
            .|::  ..:::|:..|:...::   |...:| ||.:|:   .|:|....|.|.......|
Worm   168 IPMNGMFTRMAPMLGGIPWLIL---CLRIIY-TVYIAFDPRFLLYAYKSFVTVITGNMNWIHCDD 228

  Fly   615 ------QEMAFPYRYDASNATGNLTQTV-------------AEYFNVVVLQRLHLAN------HP 654
                  .:..:..:.:.....|...:.|             ..||.   |:...|.:      :.
Worm   229 YKGVRCFDPTWSCKINEFRLNGECVKDVHIRKLAQQQDYGLLTYFG---LREYRLISIIPSQIYK 290

  Fly   655 DASGIRFHVNDRQLAFYLALIWAAVFLILC-----KGLKSLGKLAYIIYTLPLVAL--AVVTAKF 712
            :.:|:  .:.|..||       |.|||::.     ||.:....||.....||::.:  ||:   .
Worm   291 EINGL--DIMDNILA-------ALVFLLIAGFITYKGHRFFASLAGFFVFLPILGMIPAVI---L 343

  Fly   713 VYVVDPSRIQNIFAASDFDDFLVNS--------NSWTAATQETFLTWGLLGASVIAITSRSHTNA 769
            ||....||.::.     |:..|.|:        ::|..|.:.|..|..:...:::|:.||:....
Worm   344 VYYDVGSRKKHF-----FNQILKNNDITKIFELSAWLNAARVTVKTVYIADGTLMALGSRADFRH 403

  Fly   770 NKAALRRDAILLVLF-----TLIGLGLMALLALCCAQILWQHG-YVYVPGSFENPDCYTSIYSLQ 828
            |   ..:||:||...     .|:..|::.:|.: ...||:... .||..|..      ...::::
Worm   404 N---FIKDAVLLAASGATYRLLLCFGILPILYV-ANDILYPFAKTVYARGDL------VQFHAIE 458

  Fly   829 SNTNPYLLSYPRSLIPH---------YSSFIGETYRRNRTMIHVESGFQALRF------ISEIFP 878
            .    :..:.|...||.         |:...|       |:......:|.:.|      :..:||
Worm   459 L----FFSALPSYAIPGISPTVTFFVYAMLYG-------TINFAFVAYQVITFEMLINALHHLFP 512

  Fly   879 AVLSLASDSISWVWAAVAFATFAGFGLAQLCVMWKPISSALGNSTSSVLLSCVTGLL----LSIP 939
            .:|.|...|:                  ::|                ::::.||.||    ||:|
Worm   513 RLLYLKQKSV------------------RIC----------------IIMATVTLLLFLYILSLP 543

  Fly   940 F-----ATEMGISILYYVDFLLGGSWFIPIIWTAQIFG--------VFLIRGRPYNGDDLVNDLR 991
            :     ..:..::|..||..|:..:.||.:|..:.::|        :.:::..|..       .:
Worm   544 YKQLAVGYQKELAIDDYVVGLVSTTVFIQLISVSIVYGYKRLLINFLTMLKHHPVT-------YK 601

  Fly   992 LCGSMSAFLALSWNVLLPIG-LITLSVVDYKASLSNQFYYWRGKSY-------FTYWSRKMGSLI 1048
            |......||.:.|...|||. |:::..:..|   ..|.|:|....|       ..|.:||:...|
Worm   602 LVEKCRVFLYVMWAFFLPISCLVSICSIIVK---KYQIYHWPLVLYAAISALPLIYLARKLTMYI 663

  Fly  1049 QIGVLLVIPVTAIIQIYRYLAHGPPDILERIQLLYRPPEEGEEPRRPSARQTASQSRRNAL 1109
            .....    |:.:.|.:|                ::|..||.      ||:.....|.:.:
Worm   664 MRKEF----VSGLSQTHR----------------WQPANEGH------AREVEHDERASGV 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	103/563 (18%)
F56F4.3	NP_491770.3	SLC5-6-like_sbd	73..620	CDD:382020	117/640 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900