Protein Alignment bdg and Slc6a12

DIOPT Version :9

• Sequence 1: NP_611064.2
• Gene: bdg / 36747
• FlyBaseID: FBgn0034049
• Length: 1331
• Species: Drosophila melanogaster
• Sequence 2: NP_001368835.1
• Gene: Slc6a12 / 14411
• MGIID: 95628
• Length: 628
• Species: Mus musculus
• Alignment Length: 668
• Identity: 152/668 - (22%)
• Similarity: 250/668 - (37%)
• Gaps: 165/668 - (24%)

  Fly   496 QWPHAGSRTLALIGCTLGVFNMCRFAVLTI-NFGGNFLLQFLLLSVIFGIPLLWLQMCLGAKIRA 559
            ||.:.....|::.|..:|:.|:.||..|.. |.||.|.:.:.:.....|||:.:|::.||.....
Mouse    52 QWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFSCGIPVFFLEVALGQYSSQ 116

  Fly   560 GPVSMW-KISPICAGVGIALVMQQCFLALYSTVSLAWILVYLRDVFPTAARSGYRWQEMAFPYR- 622
            |.|:.| ||.|:..|:|:|.|:.:.:|.:|..:.|||.|.||        .|.:.|:   .|:.
Mouse   117 GSVTAWRKICPLLQGIGMASVVIESYLNIYYIIILAWALFYL--------FSSFTWE---LPWTT 170

  Fly   623 -------------YDASNATG-----NLTQTVAEYFNVVVL---QRLHLANHPDASGIRFHVNDR 666
                         .:.|:|.|     |.|..|.|::...||   ..:|     |...:|:
Mouse   171 CTNSWNTEHCVDFLNHSSARGVSSSENFTSPVMEFWERRVLGITSGIH-----DLGSLRW----- 225

  Fly   667 QLAFYLALIWAAVFLILCKGLKSLGKLAYIIYTLPLVALAVVTAK----------FVYVVDPSRI 721
            :||..|.|.|...:..:.||:||.||:.|...|.|.:.|.::..:          .|:.:.|..:
Mouse   226 ELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIILLIRGVTLPGAYQGIVFYLKPDLL 290

  Fly   722 QNIFAASDFDDFLVNSNSWTAATQETFLTWGLLGASVIAITS--RSHTNANKAALRRDAILLVLF 784
            :           |.:...|..|..:.|.::.:....:.|:.|  :.|.|.     .||:|
Mouse   291 R-----------LKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNC-----YRDSI----- 334

  Fly   785 TLIGLGLMALLALCCAQILWQHGYVYVPGSFENPDCYTSIYSLQSNTNPYLLSYPRSLIPHYSSF 849
                       |||         ::....||.......||....|....         ||
Mouse   335 -----------ALC---------FLNSATSFVAGFVVFSILGFMSQEQG---------IP----- 365

  Fly   850 IGETYRRNRTMIHVESGFQALRFISEIFPAVLSLASDSISWVWAAVAFATFAGFGL-AQLCVMWK 913
            |.|.         .||| ..|.||:  ||..:::.  .:|.:|:.:.|......|| :|...|..
Mouse   366 ISEV---------AESG-PGLAFIA--FPKAVTMM--PLSQLWSCLFFIMLLFLGLDSQFVCMEC 416

  Fly   914 PISSAL----------GNSTSSVLLSCVTGLLLSIPFATEMGISILYYVDFLLGGSWFIPIIWTA 968
            .:::::          |.....:|...|...|:.:...||.|:.|....|:.....  |.:::.:
Mouse   417 LVTASMDMFPQQLRKSGRRELLILAISVLCYLMGLLLVTEGGMYIFQLFDYYASSG--ICLLFLS 479

  Fly   969 QIFGVFLIRGRPYNGD---DLVNDLRLCGSMS-AFLALSWNVLLP---IGLITLSVVDYKASLSN 1026
             :|.|..| |..|..|   |.|.|  :.|... ..:.:||..|.|   :.....|:..|.....|
Mouse   480 -LFEVICI-GWVYGADRFYDNVED--MIGYRPWPLVKISWLFLTPGLCLATFFFSLSKYTPLKYN 540

  Fly  1027 QFYYWRGKSYFTYWSRKMGSLIQIGVLLVIPVTAIIQIYRYLAHGPPDILERIQLLYRP----PE 1087
            ..|      .:..|...:|.|:....:..:|:..||...:  ..|  ...:|::.|..|    |:
Mouse   541 NVY------MYPSWGYSIGWLLAFSSMACVPLFIIITFLK--TQG--SFKKRLRRLITPDPSLPQ 595

  Fly  1088 EGEEPRRP-SARQTASQS 1104
            .|..|.:. |:.|..|.|
Mouse   596 PGRRPPQDGSSAQNCSSS 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	117/521 (22%)
Slc6a12	NP_001368835.1	SLC5-6-like_sbd	49..589	CDD:382020	144/642 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900