DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sli and RLP53

DIOPT Version :9

Sequence 1:	NP_001261017.1	Gene:	sli / 36746	FlyBaseID:	FBgn0264089	Length:	2157	Species:	Drosophila melanogaster
Sequence 2:	NP_001332753.1	Gene:	RLP53 / 832764	AraportID:	AT5G27060	Length:	958	Species:	Arabidopsis thaliana

Alignment Length:	878	Identity:	198/878 - (22%)
Similarity:	301/878 - (34%)	Gaps:	289/878 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 SASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLD--EHAFKG--------LVELEIL 225
            |..::.||:|.:.:.  ||  |....|:|:|..    :|.||  .:.|||        |..|..|
plant    95 SGEVIELDLSCSSLH--GR--FHSNSSIRNLHF----LTTLDLSFNDFKGQITSSIENLSHLTYL 151

  Fly   226 TLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACD-----CHLSWLSRFLRSATRLAPYTRC--QS 283
            .|::|:.:....|..|.|.||..|.|.||.|:..     |:||.|: ||..:     |.|.  |.
plant   152 DLSSNHFSGQILNSIGNLSRLTYLNLFDNQFSGQAPSSICNLSHLT-FLDLS-----YNRFFGQF 210

  Fly   284 PSQLKGQNVADLHDQEFKCSGLTEHAPMECGAENSCPHPCRCADGIVDCREKSLTSVPVTLPDDT 348
            ||.:.|.:                                                       ..
plant   211 PSSIGGLS-------------------------------------------------------HL 220

  Fly   349 TELRLEQNFITELPPKSFSSFRRLRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNK-IKDLPSG 412
            |.|.|..|..:...|.|..:...|..:||||||.|......:..|.|||.|.|:.|. :.::||.
plant   221 TTLSLFSNKFSGQIPSSIGNLSNLTTLDLSNNNFSGQIPSFIGNLSQLTFLGLFSNNFVGEIPSS 285

  Fly   413 VFKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSLYDN--------NIQSLAN---------- 459
             |..|..|..|.::.|::|....:...:|..||||||.:|        ||.||:|
plant   286 -FGNLNQLTRLYVDDNKLSGNFPNVLLNLTGLSLLSLSNNKFTGTLPPNITSLSNLMDFDASDNA 349

  Fly   460 --GTFDA----MKSIKTVHLAKNPF--------ICDCNLRWLADYLHKN---PIETSGARCESPK 507
              |||.:    :.|:..:.|..|..        |...:..:..|..:.|   ||.:|.::.   .
plant   350 FTGTFPSFLFTIPSLTYIRLNGNQLKGTLEFGNISSPSNLYELDIGNNNFIGPIPSSISKL---V 411

  Fly   508 RMHRRRIESLREE---------KFKCSWDELRMKLSGECRMD----------------------- 540
            ::.|..|..|..:         ..|...|.....|:...|:|
plant   412 KLFRLDISHLNTQGPVDFSIFSHLKSLLDLNISHLNTTTRIDLNYFLSYFKRLLLLDLSGNHVSA 476

  Fly   541 ------SDCPAMCHCEGTTVDCTGRGLKEIPRDIPLHTTELLLNDNELG--RISSDGLFG----- 592
                  ||.|:...   .::..:|.|:.|.|        |.:...:|||  .||::.:.|
plant   477 TNKSSVSDPPSQLI---QSLYLSGCGITEFP--------EFVRTQHELGFLDISNNKIKGQVPDW 530

  Fly   593 --RLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKTLNLYDNQI 655
              |||.|..:.|..|.|.|.:..:....|.:..|....|.|.:|.: ...||..|.||:|.||..
plant   531 LWRLPILYYVNLSNNTLIGFQRPSKPEPSLLYLLGSNNNFIGKIPS-FICGLRSLNTLDLSDNNF 594

  Fly   656 SCVMPGSFEHLNSLTS-----------------------------------------------LN 673
            :..:|....||.|..|                                               ||
plant   595 NGSIPRCMGHLKSTLSVLNLRQNHLSGGLPKQIFEILRSLDVGHNQLVGKLPRSLSFFSTLEVLN 659

  Fly   674 LASNPFNCNCHLAWFAEW-----------LRKKSLNGGAARCGAPSKVRDVQIKDLPHSEF---- 723
            :.||..|..     |..|           ||..:.:|.......|    :::|.|:.|:.|
plant   660 VESNRINDT-----FPFWLSSLPKLQVLVLRSNAFHGPIHEATFP----ELRIIDISHNRFNGTL 715

  Fly   724 ---------------KCSSENSEGCLGDG-YCPPSCTCTGTVVRCSRNQLKEIPRGIPAETSELY 772
                           |...:::|..:|.| |...|      :|..::....|:.|.:...|: :.
plant   716 PTEYFVKWSAMSSLGKNEDQSNEKYMGSGLYYQDS------MVLMNKGVAMELVRILTIYTA-VD 773

  Fly   773 LESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGL 837
            ...|..|....:.|..|:.|..|.||||..:.....:..|||.|.:|.:|.|||.......|..|
plant   774 FSGNRFEGEIPKSIGLLKELLVLSLSNNAFSGHMPSSMGNLTALESLDVSKNKLTGEIPQELGDL 838

  Fly   838 NNLRVLSLHGNRIS-MLPEG---------SFED 860
            :.|..::...|::: ::|.|         :|||
plant   839 SFLAYMNFSHNQLAGLVPGGQQFLTQNCSAFED 871

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sli	NP_001261017.1	LRRNT	73..103	CDD:214470
		leucine-rich repeat	83..104	CDD:275380
		LRR_8	102..160	CDD:290566
		leucine-rich repeat	105..125	CDD:275380
		LRR_RI	<119..259	CDD:238064	31/97 (32%)
		leucine-rich repeat	126..149	CDD:275380
		LRR_8	149..208	CDD:290566	10/36 (28%)
		leucine-rich repeat	150..173	CDD:275380	1/1 (100%)
		leucine-rich repeat	174..197	CDD:275380	6/22 (27%)
		LRR_8	197..256	CDD:290566	23/68 (34%)
		leucine-rich repeat	198..221	CDD:275380	9/32 (28%)
		leucine-rich repeat	222..245	CDD:275380	7/22 (32%)
		leucine-rich repeat	246..371	CDD:275380	24/131 (18%)
		LRRCT	254..303	CDD:214507	14/55 (25%)
		LRRNT	319..350	CDD:214470	0/30 (0%)
		LRR_8	349..406	CDD:290566	21/57 (37%)
		LRR_4	371..411	CDD:289563	15/40 (38%)
		leucine-rich repeat	372..395	CDD:275380	9/22 (41%)
		leucine-rich repeat	396..415	CDD:275380	7/19 (37%)
		leucine-rich repeat	420..443	CDD:275380	5/22 (23%)
		leucine-rich repeat	444..465	CDD:275380	15/44 (34%)
		leucine-rich repeat	468..480	CDD:275378	2/19 (11%)
		LRRCT	476..525	CDD:214507	11/68 (16%)
		leucine-rich repeat	484..545	CDD:275380	15/101 (15%)
		LRRNT	542..574	CDD:214470	6/31 (19%)
		leucine-rich repeat	552..570	CDD:275380	4/17 (24%)
		leucine-rich repeat	572..596	CDD:275380	9/32 (28%)
		LRR_RI	<574..>678	CDD:238064	36/159 (23%)
		LRR_8	595..655	CDD:290566	19/59 (32%)
		leucine-rich repeat	597..620	CDD:275380	5/22 (23%)
		leucine-rich repeat	621..644	CDD:275380	6/22 (27%)
		leucine-rich repeat	645..668	CDD:275380	9/22 (41%)
		leucine-rich repeat	669..756	CDD:275380	23/164 (14%)
		LRRCT	677..726	CDD:214507	13/78 (17%)
		LRRNT	739..770	CDD:214470	5/30 (17%)
		leucine-rich repeat	757..791	CDD:275380	7/33 (21%)
		LRR_4	770..807	CDD:289563	10/36 (28%)
		LRR_8	790..850	CDD:290566	19/59 (32%)
		LRR_4	791..830	CDD:289563	15/38 (39%)
		leucine-rich repeat	792..815	CDD:275380	8/22 (36%)
		LRR_4	814..863	CDD:289563	16/57 (28%)
		leucine-rich repeat	816..839	CDD:275380	8/22 (36%)
		leucine-rich repeat	840..861	CDD:275380	7/31 (23%)
		LRRCT	872..920	CDD:214507
		EGF	935..966	CDD:278437
		EGF_CA	971..1007	CDD:238011
		EGF_CA	1009..1045	CDD:238011
		EGF_CA	1055..1086	CDD:238011
		EGF_CA	1088..1124	CDD:238011
		Laminin_G_1	1204..1335	CDD:278483
		CT	1435..1504	CDD:214482
RLP53	NP_001332753.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000