DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sli and AT4G13820

DIOPT Version :9

Sequence 1:	NP_001261017.1	Gene:	sli / 36746	FlyBaseID:	FBgn0264089	Length:	2157	Species:	Drosophila melanogaster
Sequence 2:	NP_193118.2	Gene:	AT4G13820 / 827016	AraportID:	AT4G13820	Length:	719	Species:	Arabidopsis thaliana

Alignment Length:	588	Identity:	136/588 - (23%)
Similarity:	206/588 - (35%)	Gaps:	175/588 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   531 MKLSGECRMDSDCPAMCHCEGTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLP 595
            :|.:.:.|.::||   |..:|  :.|..:..|.:..|        |:|....|.:..|....||.
plant    57 VKKTEKWRNNTDC---CSWDG--ISCDPKTGKVVELD--------LMNSFLNGPLRYDSSLFRLQ 108

  Fly   596 HLVKLELKRNQLTGIEPNAFEGASHIQELQLGE-NKIKEISNKMFLG-LHQLKTLNLYDNQISCV 658
            ||..|:|..|..:||.|::.....:::.|.||: |...:|.:.  || |..|..|:|..|..:..
plant   109 HLHNLDLGSNNFSGILPDSIGSLKYLRVLSLGDCNLFGKIPSS--LGNLTYLTNLDLSVNDFTGE 171

  Fly   659 MPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEWLRKKSLNGGAARCGAPSKVRDVQIKDLPHSEF 723
            :|.|..|||.||.|:|.|...:.|     |...|    ||           :.::.:.||..::|
plant   172 LPDSMGHLNKLTELHLGSAKLSGN-----FPSML----LN-----------LSELTLIDLGSNQF 216

  Fly   724 KCSSENSEGCLGDGYCPPSCTCTGTVV--RCSRNQLK-EIPRGIPAETSELYLESNEIEQIHYER 785
                        .|..|.:.:....:|  ...||... .||       |.|::
plant   217 ------------GGMLPSNMSSLSKLVYFGIDRNSFSGSIP-------SSLFM------------ 250

  Fly   786 IRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQCLQRH----------ALSGLNNL 840
               |.|||.|.|..|...  ....|.|::..|.|.:    |..|:.:          .|.||..|
plant   251 ---LPSLTSLVLGRNDFN--GPLDFGNISSPSNLGV----LSLLENNFNGPIPESISKLVGLFYL 306

  Fly   841 RVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWIKLDYVE-PGIARCAEPEQ 904
            . |||...:..|:...:|..|||||.:.|..........:..||..:.|.|:: .||       .
plant   307 D-LSLWNTKRGMVDFNTFLHLKSLTFLDLSYINTRSMVDISIFSPLLSLGYLDLSGI-------N 363

  Fly   905 MKDKLILSTPSSSFVCRGRVRNDILAKCNAC-FEQPCQNQAQCV------------------ALP 950
            :|....||.||.    .|.:   ||:.||.. |....:||....                  :||
plant   364 LKISSTLSLPSP----MGTL---ILSSCNIPEFPNFLENQTTLYYLDISANKIGGQVPQWLWSLP 421

  Fly   951 QREYQCLCQPGYHG--------KHCE--FMIDACYGN-----PCRNNATCTVL-EEGRFS----- 994
            :.:|..:.|..:.|        :.|.  .|:|.....     |...|:|...| .:.|||
plant   422 ELQYVNISQNSFSGFEGPADVIQRCGELLMLDISSNTFQDPFPLLPNSTTIFLGSDNRFSGEIPK 486

  Fly   995 --CQCAP---------GYTGA--RCETNIDDCLGEIKCQNNATCIDGVESYKCECQPGFSGEFCD 1046
              |:...         .:.|:  ||....:..|..:..:||                ..||||.:
plant   487 TICKLVSLDTLVLSNNNFNGSIPRCFEKFNTTLSVLHLRNN----------------NLSGEFPE 535

  Fly  1047 TKI 1049
            ..|
plant   536 ESI 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sli	NP_001261017.1	LRRNT	73..103	CDD:214470
		leucine-rich repeat	83..104	CDD:275380
		LRR_8	102..160	CDD:290566
		leucine-rich repeat	105..125	CDD:275380
		LRR_RI	<119..259	CDD:238064
		leucine-rich repeat	126..149	CDD:275380
		LRR_8	149..208	CDD:290566
		leucine-rich repeat	150..173	CDD:275380
		leucine-rich repeat	174..197	CDD:275380
		LRR_8	197..256	CDD:290566
		leucine-rich repeat	198..221	CDD:275380
		leucine-rich repeat	222..245	CDD:275380
		leucine-rich repeat	246..371	CDD:275380
		LRRCT	254..303	CDD:214507
		LRRNT	319..350	CDD:214470
		LRR_8	349..406	CDD:290566
		LRR_4	371..411	CDD:289563
		leucine-rich repeat	372..395	CDD:275380
		leucine-rich repeat	396..415	CDD:275380
		leucine-rich repeat	420..443	CDD:275380
		leucine-rich repeat	444..465	CDD:275380
		leucine-rich repeat	468..480	CDD:275378
		LRRCT	476..525	CDD:214507
		leucine-rich repeat	484..545	CDD:275380	4/13 (31%)
		LRRNT	542..574	CDD:214470	7/31 (23%)
		leucine-rich repeat	552..570	CDD:275380	3/17 (18%)
		leucine-rich repeat	572..596	CDD:275380	6/23 (26%)
		LRR_RI	<574..>678	CDD:238064	36/105 (34%)
		LRR_8	595..655	CDD:290566	20/61 (33%)
		leucine-rich repeat	597..620	CDD:275380	7/22 (32%)
		leucine-rich repeat	621..644	CDD:275380	8/24 (33%)
		leucine-rich repeat	645..668	CDD:275380	8/22 (36%)
		leucine-rich repeat	669..756	CDD:275380	17/88 (19%)
		LRRCT	677..726	CDD:214507	8/48 (17%)
		LRRNT	739..770	CDD:214470	6/33 (18%)
		leucine-rich repeat	757..791	CDD:275380	5/34 (15%)
		LRR_4	770..807	CDD:289563	8/36 (22%)
		LRR_8	790..850	CDD:290566	19/69 (28%)
		LRR_4	791..830	CDD:289563	11/38 (29%)
		leucine-rich repeat	792..815	CDD:275380	7/22 (32%)
		LRR_4	814..863	CDD:289563	14/58 (24%)
		leucine-rich repeat	816..839	CDD:275380	7/32 (22%)
		leucine-rich repeat	840..861	CDD:275380	6/20 (30%)
		LRRCT	872..920	CDD:214507	11/48 (23%)
		EGF	935..966	CDD:278437	8/57 (14%)
		EGF_CA	971..1007	CDD:238011	11/59 (19%)
		EGF_CA	1009..1045	CDD:238011	6/35 (17%)
		EGF_CA	1055..1086	CDD:238011
		EGF_CA	1088..1124	CDD:238011
		Laminin_G_1	1204..1335	CDD:278483
		CT	1435..1504	CDD:214482
AT4G13820	NP_193118.2	LRRNT_2	31..78	CDD:285463	6/25 (24%)
		LRR_RI	<79..216	CDD:238064	45/166 (27%)
		LRR_8	109..168	CDD:290566	20/60 (33%)
		leucine-rich repeat	110..133	CDD:275380	7/22 (32%)
		leucine-rich repeat	134..157	CDD:275380	8/24 (33%)
		leucine-rich repeat	158..181	CDD:275380	8/22 (36%)
		leucine-rich repeat	182..205	CDD:275380	10/42 (24%)
		leucine-rich repeat	206..229	CDD:275380	5/34 (15%)
		leucine-rich repeat	230..253	CDD:275380	8/44 (18%)
		leucine-rich repeat	254..278	CDD:275380	7/25 (28%)
		leucine-rich repeat	279..302	CDD:275380	4/26 (15%)
		leucine-rich repeat	303..328	CDD:275380	8/25 (32%)
		leucine-rich repeat	329..353	CDD:275380	5/23 (22%)
		leucine-rich repeat	354..372	CDD:275380	6/24 (25%)
		leucine-rich repeat	378..398	CDD:275380	7/22 (32%)
		leucine-rich repeat	399..422	CDD:275380	1/22 (5%)
		LRR_RI	419..>624	CDD:238064	27/136 (20%)
		leucine-rich repeat	423..448	CDD:275380	4/24 (17%)
		leucine-rich repeat	469..493	CDD:275380	6/23 (26%)
		leucine-rich repeat	494..518	CDD:275380	3/23 (13%)
		leucine-rich repeat	519..541	CDD:275380	8/36 (22%)
		leucine-rich repeat	542..565	CDD:275380
		leucine-rich repeat	566..615	CDD:275380
		leucine-rich repeat	616..634	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000