DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sli and RLP34

DIOPT Version :9

Sequence 1:	NP_001261017.1	Gene:	sli / 36746	FlyBaseID:	FBgn0264089	Length:	2157	Species:	Drosophila melanogaster
Sequence 2:	NP_001326087.1	Gene:	RLP34 / 820272	AraportID:	AT3G11010	Length:	957	Species:	Arabidopsis thaliana

Alignment Length:	952	Identity:	203/952 - (21%)
Similarity:	316/952 - (33%)	Gaps:	327/952 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 GVITEARCPRVCSCTGLNVDCS------HRG--------LTSVPR-------KISADVER----- 104
            ||...|:...|..   ||:.||      |..        ||::.|       :|::.:|.
plant    87 GVTCNAKSGEVIE---LNLSCSSLHGRFHSNSSIRNLHFLTTLDRSHNDFEGQITSSIENLSHLT 148

  Fly   105 -LELQGNNLTVIYETDFQRLTKLRMLQLTDNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFV 168
             |:|..|..:.........|::|..|.|:.||......:|..:|..|..|.|:.||......:.:
plant   149 SLDLSYNRFSGQILNSIGNLSRLTSLDLSFNQFSGQIPSSIGNLSHLTFLGLSGNRFFGQIPSSI 213

  Fly   169 TSSASLLRLDISNNVI-----TTVGRRVFKGAQSLRSLQL------------------------- 203
            .:.:.|..|.:|.|..     :::|     |..:|.:|.|
plant   214 GNLSHLTFLGLSGNRFFGQFPSSIG-----GLSNLTNLHLSYNKYSGQIPSSIGNLSQLIVLYLS 273

  Fly   204 -------------DNNQITCLD----------EHAFKGLVELEILTLNNNNLT-SLPHNIFGGLG 244
                         :.||:|.||          .:....|..|.:::|:||..| :||.|| ..|.
plant   274 VNNFYGEIPSSFGNLNQLTRLDVSFNKLGGNFPNVLLNLTGLSVVSLSNNKFTGTLPPNI-TSLS 337

  Fly   245 RLRALRLSDNPFACDC--------HLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVAD------- 294
            .|.|...|||.|....        .|::|............:....|||.|:..|:..
plant   338 NLMAFYASDNAFTGTFPSFLFIIPSLTYLGLSGNQLKGTLEFGNISSPSNLQYLNIGSNNFIGPI 402

  Fly   295 -------LHDQEFKCSGLTEHAPMECGAENSCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELR 352
                   ::.||...|.|...              ||..|..:....|||..:.::....||
plant   403 PSSISKLINLQELGISHLNTQ--------------CRPVDFSIFSHLKSLDDLRLSYLTTTT--- 450

  Fly   353 LEQNFITELPPKSFSSFRRLRRIDLSNN-----NISRIAHDALSGLKQLTTLVLYGNKIKDLPSG 412
            ::.|.|  ||     .|:.||.:|||.|     |.|.::.|..|  :.:.:|.|.|..|.|.|
plant   451 IDLNDI--LP-----YFKTLRSLDLSGNLVSATNKSSVSSDPPS--QSIQSLYLSGCGITDFP-- 504

  Fly   413 VFKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHLAKNP 477
                                   :..|..|.|..|.:.:|.|:....|....:.::..::|:.|.
plant   505 -----------------------EILRTQHELGFLDVSNNKIKGQVPGWLWTLPNLFYLNLSNNT 546

  Fly   478 FICDCNLRWLADYLHKNPIETSGARCESPKRMHRRRIESLREEKFKCSWDELRMKLSGECRMDSD 542
            ||                                                       |..|....
plant   547 FI-------------------------------------------------------GFQRPTKP 556

  Fly   543 CPAMCHCEGTTVDCTGRGLKEIPRDI----PLHTTELLLNDNELGRISSDGLFGRLP-------- 595
            .|:|.:..|:..:.||:    ||..|    .|:|.:  |:||...        |.:|
plant   557 EPSMAYLLGSNNNFTGK----IPSFICELRSLYTLD--LSDNNFS--------GSIPRCMENLKS 607

  Fly   596 HLVKLELKRNQLTGIEP-NAFEGASHIQELQLGENKIKEISNKMFLGLHQLKTLNLYDNQISCVM 659
            :|.:|.|::|.|:|..| :.||.   ::.|.:|.|::.....:.......|:.||:..|:|:.:.
plant   608 NLSELNLRQNNLSGGFPEHIFES---LRSLDVGHNQLVGKLPRSLRFFSNLEVLNVESNRINDMF 669

  Fly   660 PGSFEHLNSLTSLNLASNP----------------------FNCNCHLAWFAEWLRKKSLNGGAA 702
            |.....|..|..|.|.||.                      ||.:....:|.||.|..||  |..
plant   670 PFWLSSLQKLQVLVLRSNAFHGPINQALFPKLRIIDISHNHFNGSLPTEYFVEWSRMSSL--GTY 732

  Fly   703 RCGAPSKVRDVQIKDLPHSEFKCSSENSEGCLGDGYCPPSCTCTGTVVRCSRNQLKEIPRGIPAE 767
            ..|                       ::...||.||...|      :|..::....|:.|.:...
plant   733 EDG-----------------------SNVNYLGSGYYQDS------MVLMNKGVESELVRILTIY 768

  Fly   768 TSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKL--QCLQ 830
            |: :....|:.|....:.|..|:.|..|:||||..|.....:..|||.|.:|.:|.|||  :..|
plant   769 TA-VDFSGNKFEGEIPKSIGLLKELHVLNLSNNAFTGHIPSSIGNLTALESLDVSQNKLYGEIPQ 832

  Fly   831 RHALSGLNNLRVLSL----HGNRISMLPEG---------SFE 859
            .     :.||.:||.    |.....::|.|         |||
plant   833 E-----IGNLSLLSYMNFSHNQLTGLVPGGQQFLTQRCSSFE 869

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sli	NP_001261017.1	LRRNT	73..103	CDD:214470	10/50 (20%)
		leucine-rich repeat	83..104	CDD:275380	8/41 (20%)
		LRR_8	102..160	CDD:290566	16/63 (25%)
		leucine-rich repeat	105..125	CDD:275380	4/19 (21%)
		LRR_RI	<119..259	CDD:238064	44/193 (23%)
		leucine-rich repeat	126..149	CDD:275380	7/22 (32%)
		LRR_8	149..208	CDD:290566	15/101 (15%)
		leucine-rich repeat	150..173	CDD:275380	5/22 (23%)
		leucine-rich repeat	174..197	CDD:275380	6/27 (22%)
		LRR_8	197..256	CDD:290566	24/107 (22%)
		leucine-rich repeat	198..221	CDD:275380	9/70 (13%)
		leucine-rich repeat	222..245	CDD:275380	10/23 (43%)
		leucine-rich repeat	246..371	CDD:275380	30/146 (21%)
		LRRCT	254..303	CDD:214507	11/70 (16%)
		LRRNT	319..350	CDD:214470	7/30 (23%)
		LRR_8	349..406	CDD:290566	19/61 (31%)
		LRR_4	371..411	CDD:289563	15/44 (34%)
		leucine-rich repeat	372..395	CDD:275380	10/27 (37%)
		leucine-rich repeat	396..415	CDD:275380	6/18 (33%)
		leucine-rich repeat	420..443	CDD:275380	1/22 (5%)
		leucine-rich repeat	444..465	CDD:275380	5/20 (25%)
		leucine-rich repeat	468..480	CDD:275378	3/11 (27%)
		LRRCT	476..525	CDD:214507	3/48 (6%)
		leucine-rich repeat	484..545	CDD:275380	2/60 (3%)
		LRRNT	542..574	CDD:214470	10/35 (29%)
		leucine-rich repeat	552..570	CDD:275380	5/21 (24%)
		leucine-rich repeat	572..596	CDD:275380	6/31 (19%)
		LRR_RI	<574..>678	CDD:238064	28/112 (25%)
		LRR_8	595..655	CDD:290566	17/68 (25%)
		leucine-rich repeat	597..620	CDD:275380	9/23 (39%)
		leucine-rich repeat	621..644	CDD:275380	3/22 (14%)
		leucine-rich repeat	645..668	CDD:275380	7/22 (32%)
		leucine-rich repeat	669..756	CDD:275380	21/108 (19%)
		LRRCT	677..726	CDD:214507	11/70 (16%)
		LRRNT	739..770	CDD:214470	5/30 (17%)
		leucine-rich repeat	757..791	CDD:275380	7/33 (21%)
		LRR_4	770..807	CDD:289563	11/36 (31%)
		LRR_8	790..850	CDD:290566	22/65 (34%)
		LRR_4	791..830	CDD:289563	16/40 (40%)
		leucine-rich repeat	792..815	CDD:275380	9/22 (41%)
		LRR_4	814..863	CDD:289563	18/61 (30%)
		leucine-rich repeat	816..839	CDD:275380	7/24 (29%)
		leucine-rich repeat	840..861	CDD:275380	9/33 (27%)
		LRRCT	872..920	CDD:214507
		EGF	935..966	CDD:278437
		EGF_CA	971..1007	CDD:238011
		EGF_CA	1009..1045	CDD:238011
		EGF_CA	1055..1086	CDD:238011
		EGF_CA	1088..1124	CDD:238011
		Laminin_G_1	1204..1335	CDD:278483
		CT	1435..1504	CDD:214482
RLP34	NP_001326087.1	LRRNT_2	40..91	CDD:311940	2/3 (67%)
		PLN00113	75..>717	CDD:331614	155/761 (20%)
		leucine-rich repeat	123..146	CDD:275380	5/22 (23%)
		leucine-rich repeat	147..170	CDD:275380	4/22 (18%)
		leucine-rich repeat	171..194	CDD:275380	7/22 (32%)
		leucine-rich repeat	195..218	CDD:275380	5/22 (23%)
		leucine-rich repeat	219..242	CDD:275380	6/27 (22%)
		leucine-rich repeat	243..266	CDD:275380	3/22 (14%)
		leucine-rich repeat	267..290	CDD:275380	0/22 (0%)
		leucine-rich repeat	291..314	CDD:275380	4/22 (18%)
		leucine-rich repeat	315..362	CDD:275380	16/47 (34%)
		leucine-rich repeat	388..411	CDD:275380	2/22 (9%)
		leucine-rich repeat	412..437	CDD:275380	7/38 (18%)
		leucine-rich repeat	463..489	CDD:275380	10/27 (37%)
		leucine-rich repeat	490..512	CDD:275380	7/46 (15%)
		leucine-rich repeat	513..536	CDD:275380	5/22 (23%)
		leucine-rich repeat	560..583	CDD:275380	7/26 (27%)
		PLN00113	566..>880	CDD:331614	86/358 (24%)
		leucine-rich repeat	584..608	CDD:275380	7/33 (21%)
		leucine-rich repeat	609..630	CDD:275380	8/20 (40%)
		leucine-rich repeat	631..654	CDD:275380	3/22 (14%)
		leucine-rich repeat	655..678	CDD:275380	7/22 (32%)
		leucine-rich repeat	679..700	CDD:275380	5/20 (25%)
		leucine-rich repeat	701..737	CDD:275380	10/60 (17%)
		leucine-rich repeat	738..791	CDD:275380	13/59 (22%)
		leucine-rich repeat	792..815	CDD:275380	9/22 (41%)
		leucine-rich repeat	816..839	CDD:275380	9/27 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000