DRSC/TRiP Functional Genomics Resources

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Protein Alignment sli and lrtm2a

DIOPT Version :9

Sequence 1:NP_001261017.1 Gene:sli / 36746 FlyBaseID:FBgn0264089 Length:2157 Species:Drosophila melanogaster
Sequence 2:XP_001923104.1 Gene:lrtm2a / 557289 ZFINID:ZDB-GENE-041210-218 Length:371 Species:Danio rerio


Alignment Length:210 Identity:64/210 - (30%)
Similarity:102/210 - (48%) Gaps:7/210 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly   319 CPHPCRCADGIVDCREKSLTSVP--VTLPDDTTELRLEQNFITELPPKSFSSFRRLRRIDLSNNN 381
            ||..|.|.....:|..:||.|||  .:||:.|..|.|..|.::.||..:|::...|..:|||||.
Zfish    39 CPSECVCNSLEANCSGRSLVSVPALTSLPEGTHTLLLANNRLSSLPLSAFANLSTLETLDLSNNY 103

  Fly   382 ISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKDAFRDLHSLSL 446
            :..:.......|..|:.|.|..|.:..|...:|:||..|:.|.|:.|.::.:......:|..|:.
Zfish   104 LDNLPSRLFRELSNLSELSLRNNSLTVLDRELFRGLTHLRKLDLSLNGLAAVPLGLLDELQQLTW 168

  Fly   447 LSLYDNNIQSLANGTFDAMKSIKTVHLAKNPFICDCNLR----WLADYLHKNPIETSGARCESPK 507
            |||..|.:.:|...||:.:.:::.:.|..||:.||||||    |:...:::... .....|..||
Zfish   169 LSLAGNRLHALERATFEPLVNLQHLELGMNPWECDCNLRDFKHWMEWLIYRGGY-VDAVECTLPK 232

  Fly   508 RMHRRRIESLREEKF 522
            .:..|.|..:..|.|
Zfish   233 DLRGRDIRGVPVEMF 247

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sliNP_001261017.1 LRRNT 73..103 CDD:214470
leucine-rich repeat 83..104 CDD:275380
LRR_8 102..160 CDD:290566
leucine-rich repeat 105..125 CDD:275380
LRR_RI <119..259 CDD:238064
leucine-rich repeat 126..149 CDD:275380
LRR_8 149..208 CDD:290566
leucine-rich repeat 150..173 CDD:275380
leucine-rich repeat 174..197 CDD:275380
LRR_8 197..256 CDD:290566
leucine-rich repeat 198..221 CDD:275380
leucine-rich repeat 222..245 CDD:275380
leucine-rich repeat 246..371 CDD:275380 19/53 (36%)
LRRCT 254..303 CDD:214507
LRRNT 319..350 CDD:214470 13/32 (41%)
LRR_8 349..406 CDD:290566 17/56 (30%)
LRR_4 371..411 CDD:289563 12/39 (31%)
leucine-rich repeat 372..395 CDD:275380 7/22 (32%)
leucine-rich repeat 396..415 CDD:275380 5/18 (28%)
leucine-rich repeat 420..443 CDD:275380 5/22 (23%)
leucine-rich repeat 444..465 CDD:275380 8/20 (40%)
leucine-rich repeat 468..480 CDD:275378 3/11 (27%)
LRRCT 476..525 CDD:214507 16/51 (31%)
leucine-rich repeat 484..545 CDD:275380 10/43 (23%)
LRRNT 542..574 CDD:214470
leucine-rich repeat 552..570 CDD:275380
leucine-rich repeat 572..596 CDD:275380
LRR_RI <574..>678 CDD:238064
LRR_8 595..655 CDD:290566
leucine-rich repeat 597..620 CDD:275380
leucine-rich repeat 621..644 CDD:275380
leucine-rich repeat 645..668 CDD:275380
leucine-rich repeat 669..756 CDD:275380
LRRCT 677..726 CDD:214507
LRRNT 739..770 CDD:214470
leucine-rich repeat 757..791 CDD:275380
LRR_4 770..807 CDD:289563
LRR_8 790..850 CDD:290566
LRR_4 791..830 CDD:289563
leucine-rich repeat 792..815 CDD:275380
LRR_4 814..863 CDD:289563
leucine-rich repeat 816..839 CDD:275380
leucine-rich repeat 840..861 CDD:275380
LRRCT 872..920 CDD:214507
EGF 935..966 CDD:278437
EGF_CA 971..1007 CDD:238011
EGF_CA 1009..1045 CDD:238011
EGF_CA 1055..1086 CDD:238011
EGF_CA 1088..1124 CDD:238011
Laminin_G_1 1204..1335 CDD:278483
CT 1435..1504 CDD:214482
lrtm2aXP_001923104.1 LRR 44..>201 CDD:227223 47/156 (30%)
leucine-rich repeat 71..93 CDD:275380 6/21 (29%)
leucine-rich repeat 94..117 CDD:275380 7/22 (32%)
leucine-rich repeat 118..141 CDD:275380 8/22 (36%)
leucine-rich repeat 142..165 CDD:275380 5/22 (23%)
leucine-rich repeat 166..189 CDD:275380 8/22 (36%)
PCC 171..>244 CDD:188093 20/73 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45836
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
22.010

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