DRSC/TRiP Functional Genomics Resources

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Protein Alignment sli and rtn4rl1b

DIOPT Version :9

Sequence 1:NP_001261017.1 Gene:sli / 36746 FlyBaseID:FBgn0264089 Length:2157 Species:Drosophila melanogaster
Sequence 2:NP_982347.1 Gene:rtn4rl1b / 403308 ZFINID:ZDB-GENE-040310-3 Length:478 Species:Danio rerio


Alignment Length:459 Identity:108/459 - (23%)
Similarity:152/459 - (33%) Gaps:178/459 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    73 CPRVCSC--TGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQLTDNQ 135
            |||.|.|  ....|.|......|||..|....||:.||.|.:..:.:..|...|.  .|.:..|.
Zfish    23 CPRHCICYMAPSTVSCQAHNFLSVPEGIPPHSERIFLQNNKIHRLLQGHFSPTTV--TLWIYSNN 85

  Fly   136 IHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRS 200
            |..||.::||....||.|.|.:||.                                     |||
Zfish    86 ITYIEPSTFQGFTLLEELDLGDNRY-------------------------------------LRS 113

  Fly   201 LQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWL 265
            |..:          .|.||..|..|.|....|::||:|||.||..|:.|.|.||      ||.:|
Zfish   114 LSAE----------TFHGLGRLHALHLYRCGLSALPNNIFQGLRNLQYLYLQDN------HLEYL 162

  Fly   266 SRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTEHAPMECGAENSCPHPCRCADGIV 330
            .                                                                
Zfish   163 Q---------------------------------------------------------------- 163

  Fly   331 DCREKSLTSVPVTLPDDTTELRLEQNFITELPPKSFSSFRRLRRIDLSNNNISRIAHDALSGLKQ 395
                           ||..                         :||.|                
Zfish   164 ---------------DDLF-------------------------VDLHN---------------- 172

  Fly   396 LTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSLANG 460
            |:.|.|:||::..|....|:|||:|..|||:.|::..:.:.||.||..|:.|.|::|::..||..
Zfish   173 LSHLFLHGNRLWSLHQNTFRGLGALDRLLLHHNQLQWVDRLAFHDLRRLTTLYLFNNSLTELAGE 237

  Fly   461 TFDAMKSIKTVHLAKNPFICDCNLRWLADYLHKNPIETSGARCESPKRMHRRRIESLREEKF-KC 524
            ....:.:::.:.|..||:.|||....|.|:|.|....||...|.:|..:..:.::.||:|.| .|
Zfish   238 CLTQLPALEYLRLNDNPWECDCKALSLWDWLKKFRGSTSSVGCVAPAELAGKDLKQLRKEDFPNC 302

  Fly   525 SWDE 528
            |..|
Zfish   303 SGSE 306

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sliNP_001261017.1 LRRNT 73..103 CDD:214470 11/31 (35%)
leucine-rich repeat 83..104 CDD:275380 6/20 (30%)
LRR_8 102..160 CDD:290566 19/57 (33%)
leucine-rich repeat 105..125 CDD:275380 4/19 (21%)
LRR_RI <119..259 CDD:238064 38/139 (27%)
leucine-rich repeat 126..149 CDD:275380 7/22 (32%)
LRR_8 149..208 CDD:290566 10/58 (17%)
leucine-rich repeat 150..173 CDD:275380 6/22 (27%)
leucine-rich repeat 174..197 CDD:275380 0/22 (0%)
LRR_8 197..256 CDD:290566 23/58 (40%)
leucine-rich repeat 198..221 CDD:275380 7/22 (32%)
leucine-rich repeat 222..245 CDD:275380 11/22 (50%)
leucine-rich repeat 246..371 CDD:275380 10/124 (8%)
LRRCT 254..303 CDD:214507 4/48 (8%)
LRRNT 319..350 CDD:214470 2/30 (7%)
LRR_8 349..406 CDD:290566 8/56 (14%)
LRR_4 371..411 CDD:289563 9/39 (23%)
leucine-rich repeat 372..395 CDD:275380 3/22 (14%)
leucine-rich repeat 396..415 CDD:275380 6/18 (33%)
leucine-rich repeat 420..443 CDD:275380 9/22 (41%)
leucine-rich repeat 444..465 CDD:275380 6/20 (30%)
leucine-rich repeat 468..480 CDD:275378 3/11 (27%)
LRRCT 476..525 CDD:214507 17/49 (35%)
leucine-rich repeat 484..545 CDD:275380 15/46 (33%)
LRRNT 542..574 CDD:214470
leucine-rich repeat 552..570 CDD:275380
leucine-rich repeat 572..596 CDD:275380
LRR_RI <574..>678 CDD:238064
LRR_8 595..655 CDD:290566
leucine-rich repeat 597..620 CDD:275380
leucine-rich repeat 621..644 CDD:275380
leucine-rich repeat 645..668 CDD:275380
leucine-rich repeat 669..756 CDD:275380
LRRCT 677..726 CDD:214507
LRRNT 739..770 CDD:214470
leucine-rich repeat 757..791 CDD:275380
LRR_4 770..807 CDD:289563
LRR_8 790..850 CDD:290566
LRR_4 791..830 CDD:289563
leucine-rich repeat 792..815 CDD:275380
LRR_4 814..863 CDD:289563
leucine-rich repeat 816..839 CDD:275380
leucine-rich repeat 840..861 CDD:275380
LRRCT 872..920 CDD:214507
EGF 935..966 CDD:278437
EGF_CA 971..1007 CDD:238011
EGF_CA 1009..1045 CDD:238011
EGF_CA 1055..1086 CDD:238011
EGF_CA 1088..1124 CDD:238011
Laminin_G_1 1204..1335 CDD:278483
CT 1435..1504 CDD:214482
rtn4rl1bNP_982347.1 leucine-rich repeat 35..56 CDD:275380 6/20 (30%)
LRR_8 52..109 CDD:290566 18/58 (31%)
leucine-rich repeat 57..75 CDD:275380 4/17 (24%)
leucine-rich repeat 77..99 CDD:275380 7/23 (30%)
LRR_RI 100..>254 CDD:238064 63/326 (19%)
LRR_8 100..159 CDD:290566 29/111 (26%)
leucine-rich repeat 100..124 CDD:275380 13/70 (19%)
leucine-rich repeat 125..148 CDD:275380 11/22 (50%)
LRR_8 147..207 CDD:290566 28/185 (15%)
LRR_4 148..186 CDD:289563 18/163 (11%)
leucine-rich repeat 149..172 CDD:275380 12/132 (9%)
leucine-rich repeat 173..196 CDD:275380 9/22 (41%)
LRR_8 197..254 CDD:290566 16/56 (29%)
leucine-rich repeat 197..220 CDD:275380 9/22 (41%)
leucine-rich repeat 221..244 CDD:275380 6/22 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45836
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
33.010

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