DRSC/TRiP Functional Genomics Resources

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Protein Alignment sli and Lrrc24

DIOPT Version :9

Sequence 1:NP_001261017.1 Gene:sli / 36746 FlyBaseID:FBgn0264089 Length:2157 Species:Drosophila melanogaster
Sequence 2:NP_001129368.1 Gene:Lrrc24 / 362945 RGDID:1308720 Length:521 Species:Rattus norvegicus


Alignment Length:416 Identity:92/416 - (22%)
Similarity:130/416 - (31%) Gaps:168/416 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   543 CPAMCHCEGTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQL 607
            |||.|.|...||:|....|:.:|..||..|..|.|.||.:..: ..|....|..|..|.|..|.|
  Rat    31 CPAACRCYSATVECGALRLRVVPPGIPPGTQTLFLQDNSIAHL-EQGALAPLAALRHLYLHNNTL 94

  Fly   608 TGIEPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSL 672
            ..:|..||.....:.||.|..|:::.:....|:||.||:.|.|..||::.::..:|.||      
  Rat    95 RALESGAFRAQPRLLELALTGNRLRGLRGGAFVGLVQLRVLYLAGNQLAKLLDFTFLHL------ 153

  Fly   673 NLASNPFNCNCHLAWFAEWLRKKSLNGGAARCGAPSKVRDVQIKDLPHSEFKCSSENSEGCLGDG 737
                                                                             
  Rat   154 ----------------------------------------------------------------- 153

  Fly   738 YCPPSCTCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQI 802
                                   ||     ..||:|:.|.||.:..:.:..|.||..||||.||:
  Rat   154 -----------------------PR-----LQELHLQENSIELLEDQALAGLSSLALLDLSRNQL 190

  Fly   803 TILSNYTFANLTKLSTLIISYNKLQCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKSLTHI 867
            ..:|                        :.||..|::|:||                        
  Rat   191 GTIS------------------------KEALQPLSSLQVL------------------------ 207

  Fly   868 ALGSNPLYCDCGLKWFSDWIK------LDYVEPGIARCAEPEQMKDKLILSTPSSSFVC------ 920
            .|..||..|||.|.|...|||      |...:..|. ||||.::..:.:|.....|.:|      
  Rat   208 RLTENPWRCDCALHWLGSWIKEGGRRLLSSRDKKIT-CAEPPRLALQSLLEVSGGSLICIPPSVN 271

  Fly   921 ------RGRVRNDILAKCNAC-FEQP 939
                  ...:..|:...|.|. :.||
  Rat   272 AEPPELTANLGEDLQVACQASGYPQP 297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sliNP_001261017.1 LRRNT 73..103 CDD:214470
leucine-rich repeat 83..104 CDD:275380
LRR_8 102..160 CDD:290566
leucine-rich repeat 105..125 CDD:275380
LRR_RI <119..259 CDD:238064
leucine-rich repeat 126..149 CDD:275380
LRR_8 149..208 CDD:290566
leucine-rich repeat 150..173 CDD:275380
leucine-rich repeat 174..197 CDD:275380
LRR_8 197..256 CDD:290566
leucine-rich repeat 198..221 CDD:275380
leucine-rich repeat 222..245 CDD:275380
leucine-rich repeat 246..371 CDD:275380
LRRCT 254..303 CDD:214507
LRRNT 319..350 CDD:214470
LRR_8 349..406 CDD:290566
LRR_4 371..411 CDD:289563
leucine-rich repeat 372..395 CDD:275380
leucine-rich repeat 396..415 CDD:275380
leucine-rich repeat 420..443 CDD:275380
leucine-rich repeat 444..465 CDD:275380
leucine-rich repeat 468..480 CDD:275378
LRRCT 476..525 CDD:214507
leucine-rich repeat 484..545 CDD:275380 1/1 (100%)
LRRNT 542..574 CDD:214470 13/30 (43%)
leucine-rich repeat 552..570 CDD:275380 6/17 (35%)
leucine-rich repeat 572..596 CDD:275380 7/23 (30%)
LRR_RI <574..>678 CDD:238064 30/103 (29%)
LRR_8 595..655 CDD:290566 20/59 (34%)
leucine-rich repeat 597..620 CDD:275380 8/22 (36%)
leucine-rich repeat 621..644 CDD:275380 7/22 (32%)
leucine-rich repeat 645..668 CDD:275380 8/22 (36%)
leucine-rich repeat 669..756 CDD:275380 0/86 (0%)
LRRCT 677..726 CDD:214507 0/48 (0%)
LRRNT 739..770 CDD:214470 2/30 (7%)
leucine-rich repeat 757..791 CDD:275380 9/33 (27%)
LRR_4 770..807 CDD:289563 15/36 (42%)
LRR_8 790..850 CDD:290566 15/59 (25%)
LRR_4 791..830 CDD:289563 9/38 (24%)
leucine-rich repeat 792..815 CDD:275380 8/22 (36%)
LRR_4 814..863 CDD:289563 6/48 (13%)
leucine-rich repeat 816..839 CDD:275380 3/22 (14%)
leucine-rich repeat 840..861 CDD:275380 3/20 (15%)
LRRCT 872..920 CDD:214507 18/53 (34%)
EGF 935..966 CDD:278437 2/6 (33%)
EGF_CA 971..1007 CDD:238011
EGF_CA 1009..1045 CDD:238011
EGF_CA 1055..1086 CDD:238011
EGF_CA 1088..1124 CDD:238011
Laminin_G_1 1204..1335 CDD:278483
CT 1435..1504 CDD:214482
Lrrc24NP_001129368.1 leucine-rich repeat 61..83 CDD:275380 6/22 (27%)
PPP1R42 63..>212 CDD:411060 55/296 (19%)
LRR_8 84..142 CDD:404697 20/57 (35%)
leucine-rich repeat 84..107 CDD:275380 8/22 (36%)
leucine-rich repeat 108..131 CDD:275380 7/22 (32%)
leucine-rich repeat 132..155 CDD:275380 8/116 (7%)
leucine-rich repeat 156..179 CDD:275380 7/22 (32%)
leucine-rich repeat 180..203 CDD:275380 11/46 (24%)
PCC 188..>259 CDD:188093 27/119 (23%)
Ig_3 267..357 CDD:404760 5/31 (16%)
Ig strand A 267..271 CDD:409353 0/3 (0%)
Ig strand A' 276..280 CDD:409353 0/3 (0%)
Ig strand B 283..292 CDD:409353 2/8 (25%)
Ig strand C 298..304 CDD:409353 92/416 (22%)
Ig strand D 330..333 CDD:409353
Ig strand E 336..342 CDD:409353
Ig strand F 349..357 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4237
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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