Protein Alignment sli and Lrrc3

DIOPT Version :10

• Sequence 1: NP_001261017.1
• Gene: sli / 36746
• FlyBaseID: FBgn0264089
• Length: 2157
• Species: Drosophila melanogaster
• Sequence 2: NP_663712.1
• Gene: Lrrc3 / 246773
• RGDID: 628861
• Length: 257
• Species: Rattus norvegicus
• Alignment Length: 216
• Identity: 63/216 - (29%)
• Similarity: 85/216 - (39%)
• Gaps: 65/216 - (30%)

  Fly   535 GEC-------RMDSDCPAMCHCE----GTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSD 588
            |.|       |:.:.||..|.|.    ...|.|:.|||:|||||||.:|..|.|:.|.:.|: .:
  Rat    18 GSCFFILFCLRLGASCPQSCQCPDHAGAVAVHCSSRGLQEIPRDIPANTVLLKLDANRISRV-PN 81

  Fly   589 GLFGRLPHLVKLELKRNQLTGIEPNAFEG-ASHIQELQLGENKIKEISNKMFLGLHQLKTLNLYD 652
            |.|..||.|.:|:|..|.:..|.|.||.| |..::.|.|..|:|:.|. |..||....|
  Rat    82 GAFQHLPQLRELDLSHNAIEAIGPAAFSGLAGGLRLLDLSHNRIRRIP-KDALGKLSAK------ 139

  Fly   653 NQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEWLRK----------------------- 694
                               :.|:.||.:|.|.|. .|.|..|
  Rat   140 -------------------IRLSHNPLHCECALQ-EALWELKLDPDSVDEIACHTSAQEQFVGKP 184

  Fly   695 --KSLNGGAARCGAPSKVRDV 713
              :.|:.||:.|....|..||
  Rat   185 LIQVLDSGASFCSTHRKTTDV 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sli	NP_001261017.1	LRRNT	73..103	CDD:214470
		leucine-rich repeat	83..104	CDD:275380
		LRR	98..>409	CDD:443914
		leucine-rich repeat	105..125	CDD:275380
		leucine-rich repeat	126..149	CDD:275380
		leucine-rich repeat	150..173	CDD:275380
		leucine-rich repeat	174..197	CDD:275380
		leucine-rich repeat	198..221	CDD:275380
		leucine-rich repeat	222..245	CDD:275380
		leucine-rich repeat	246..371	CDD:275380
		LRRCT	254..303	CDD:214507
		LRR	<329..>498	CDD:443914
		leucine-rich repeat	372..395	CDD:275380
		leucine-rich repeat	396..415	CDD:275380
		leucine-rich repeat	420..443	CDD:275380
		leucine-rich repeat	444..465	CDD:275380
		leucine-rich repeat	468..480	CDD:275378
		LRRCT	476..525	CDD:214507
		leucine-rich repeat	484..545	CDD:275380	4/16 (25%)
		LRRNT	542..574	CDD:214470	17/35 (49%)
		leucine-rich repeat	552..570	CDD:275380	11/17 (65%)
		LRR	572..>874	CDD:443914	44/168 (26%)
		leucine-rich repeat	572..596	CDD:275380	8/23 (35%)
		leucine-rich repeat	597..620	CDD:275380	10/23 (43%)
		leucine-rich repeat	621..644	CDD:275380	8/22 (36%)
		leucine-rich repeat	645..668	CDD:275380	1/22 (5%)
		leucine-rich repeat	669..756	CDD:275380	16/70 (23%)
		LRRCT	677..726	CDD:214507	15/62 (24%)
		leucine-rich repeat	757..791	CDD:275380
		leucine-rich repeat	792..815	CDD:275380
		leucine-rich repeat	816..839	CDD:275380
		leucine-rich repeat	840..861	CDD:275380
		PCC	845..>986	CDD:188093
		EGF_CA	971..1007	CDD:238011
		EGF_CA	1009..1045	CDD:238011
		EGF_CA	1055..1086	CDD:238011
		EGF_CA	1088..1124	CDD:238011
		Laminin_G_1	1204..1335	CDD:395008
		CT	1435..1504	CDD:214482
Lrrc3	NP_663712.1	LRRNT	33..63	CDD:396168	14/29 (48%)
		leucine-rich repeat	48..65	CDD:275378	12/16 (75%)
		LRR	<49..>147	CDD:443914	41/124 (33%)
		LRR 1	65..86		7/21 (33%)
		leucine-rich repeat	66..89	CDD:275378	8/23 (35%)
		LRR 2	89..110		8/20 (40%)
		leucine-rich repeat	90..114	CDD:275378	10/23 (43%)
		LRR 3	114..135		7/21 (33%)
		leucine-rich repeat	115..138	CDD:275378	8/23 (35%)