DRSC/TRiP Functional Genomics Resources

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Protein Alignment sli and Lrrc3b

DIOPT Version :9

Sequence 1:NP_001261017.1 Gene:sli / 36746 FlyBaseID:FBgn0264089 Length:2157 Species:Drosophila melanogaster
Sequence 2:NP_666164.1 Gene:Lrrc3b / 218763 MGIID:2384996 Length:259 Species:Mus musculus


Alignment Length:147 Identity:52/147 - (35%)
Similarity:72/147 - (48%) Gaps:30/147 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   739 CPPSCTCT---GTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIHYERIRHLRSLTRLDLSNN 800
            ||..|.|:   |..|.||...||||||.:|.||..|||:|                        |
Mouse    34 CPKGCLCSSSGGLNVTCSNANLKEIPRDLPPETVLLYLDS------------------------N 74

  Fly   801 QITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGL-NNLRVLSLHGNRISMLPEGSFEDLKSL 864
            |||.:.|..|.:|.:|..|.:|.|.::.:..||..|: ..|:.|.|..|||..:.:.:|.:||:.
Mouse    75 QITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLDLSDNRIQSVHKNAFNNLKAR 139

  Fly   865 THIALGSNPLYCDCGLK 881
            ..||  :||.:|||.|:
Mouse   140 ARIA--NNPWHCDCTLQ 154

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sliNP_001261017.1 LRRNT 73..103 CDD:214470
leucine-rich repeat 83..104 CDD:275380
LRR_8 102..160 CDD:290566
leucine-rich repeat 105..125 CDD:275380
LRR_RI <119..259 CDD:238064
leucine-rich repeat 126..149 CDD:275380
LRR_8 149..208 CDD:290566
leucine-rich repeat 150..173 CDD:275380
leucine-rich repeat 174..197 CDD:275380
LRR_8 197..256 CDD:290566
leucine-rich repeat 198..221 CDD:275380
leucine-rich repeat 222..245 CDD:275380
leucine-rich repeat 246..371 CDD:275380
LRRCT 254..303 CDD:214507
LRRNT 319..350 CDD:214470
LRR_8 349..406 CDD:290566
LRR_4 371..411 CDD:289563
leucine-rich repeat 372..395 CDD:275380
leucine-rich repeat 396..415 CDD:275380
leucine-rich repeat 420..443 CDD:275380
leucine-rich repeat 444..465 CDD:275380
leucine-rich repeat 468..480 CDD:275378
LRRCT 476..525 CDD:214507
leucine-rich repeat 484..545 CDD:275380
LRRNT 542..574 CDD:214470
leucine-rich repeat 552..570 CDD:275380
leucine-rich repeat 572..596 CDD:275380
LRR_RI <574..>678 CDD:238064
LRR_8 595..655 CDD:290566
leucine-rich repeat 597..620 CDD:275380
leucine-rich repeat 621..644 CDD:275380
leucine-rich repeat 645..668 CDD:275380
leucine-rich repeat 669..756 CDD:275380 8/19 (42%)
LRRCT 677..726 CDD:214507
LRRNT 739..770 CDD:214470 17/33 (52%)
leucine-rich repeat 757..791 CDD:275380 13/33 (39%)
LRR_4 770..807 CDD:289563 8/36 (22%)
LRR_8 790..850 CDD:290566 18/60 (30%)
LRR_4 791..830 CDD:289563 11/38 (29%)
leucine-rich repeat 792..815 CDD:275380 7/22 (32%)
LRR_4 814..863 CDD:289563 15/49 (31%)
leucine-rich repeat 816..839 CDD:275380 7/23 (30%)
leucine-rich repeat 840..861 CDD:275380 7/20 (35%)
LRRCT 872..920 CDD:214507 6/10 (60%)
EGF 935..966 CDD:278437
EGF_CA 971..1007 CDD:238011
EGF_CA 1009..1045 CDD:238011
EGF_CA 1055..1086 CDD:238011
EGF_CA 1088..1124 CDD:238011
Laminin_G_1 1204..1335 CDD:278483
CT 1435..1504 CDD:214482
Lrrc3bNP_666164.1 LRRNT 33..68 CDD:214470 17/33 (52%)
LRR 1 65..86 12/44 (27%)
leucine-rich repeat 66..89 CDD:275378 12/46 (26%)
LRR_8 69..125 CDD:404697 22/79 (28%)
LRR 2 89..110 6/20 (30%)
leucine-rich repeat 90..113 CDD:275378 7/22 (32%)
LRR 3 114..135 7/20 (35%)
leucine-rich repeat 115..138 CDD:275378 8/22 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4237
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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