DRSC/TRiP Functional Genomics Resources

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Protein Alignment sli and slitrk4

DIOPT Version :9

Sequence 1:NP_001261017.1 Gene:sli / 36746 FlyBaseID:FBgn0264089 Length:2157 Species:Drosophila melanogaster
Sequence 2:XP_004916941.2 Gene:slitrk4 / 100497316 XenbaseID:XB-GENE-983538 Length:851 Species:Xenopus tropicalis


Alignment Length:836 Identity:191/836 - (22%)
Similarity:314/836 - (37%) Gaps:235/836 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    76 VCSCTGLN----VDCSHRGLTSVPRKIS---ADVERLELQGNNLTVIYETDFQRLTKLRMLQLTD 133
            ||||..:.    |:|....|.. |.::.   ::...|..|.|.|.::|...|...|....|||.:
 Frog    44 VCSCLSVENVMYVNCEKVALYR-PNQLKPPPSNFYHLNFQNNLLIILYPNTFLNFTHAVSLQLGN 107

  Fly   134 NQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSL 198
            |::..||..:||.|.:|::|.||||.||            :||.|            .|.|.::|
 Frog   108 NKLQNIEGGAFQGLSALKQLHLNNNELK------------VLRAD------------TFLGIENL 148

  Fly   199 RSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIF-----------GG---------- 242
            ..||.|.|.|..::..||..|.:|::|.||:|.:::||.|||           |.          
 Frog   149 EYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISALPDNIFRFASLTHLDIRGNRIQKMPYIGV 213

  Fly   243 ---LGRLRALRLSDNPFACDCHL----SWLSRFLRSATRLAPY------TRCQSPSQLKGQNVAD 294
               :||:..|:|.|||:.|.|.|    :||...        ||      ..|::||.|.|:.:.:
 Frog   214 LEHIGRVVELQLEDNPWNCTCDLLPLKAWLENM--------PYNIYIGEAICETPSDLYGRLLKE 270

  Fly   295 LHDQEFKCSG--------------------------------LTEHAPMECG-AENS-------- 318
            .:.||....|                                |...||.... ::||        
 Frog   271 TNKQELCSMGTGSDFDVRILPPSMETTFTTPGGQPAQTSLHRLVTKAPKTTNPSKNSGIVSGKSV 335

  Fly   319 --------------------CPHPCRCAD-----GI-VDCREKSLTSVPVTLPD--DTTELRLEQ 355
                                ||.||.|..     |: |:|:|:::.|:...:|.  :..:|.:..
 Frog   336 SNHSLSQIVSFQTRIPPFSPCPSPCMCKTYPSDLGLSVNCQERNIKSMAELIPKPLNAKKLHVNG 400

  Fly   356 NFITELPPKSFSSFRRLRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSL 420
            |:|..:....|..|..|..:.|.:|.::.|..:....|..|..|.|.||:|:.|...:|.||.:|
 Frog   401 NYIKHVEQSDFVDFEGLDLLHLGSNQLTNIQGNVFCNLTNLRRLYLNGNQIERLSPEIFAGLHNL 465

  Fly   421 QLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSL------------------------ANGT 461
            |.|.|..|.|..|....|..:.:|.||.|.:|.::||                        .:|.
 Frog   466 QYLYLEYNIIKEILGGTFESMPNLQLLYLNNNLLRSLPAYIFSGVPLARLNIRNNHFMYLPVSGV 530

  Fly   462 FDAMKSIKTVHLAKNPFICDCNLRWLADYLHK--NPIETSGARCESPKRMHRRRIESLREEKFKC 524
            .|.::|:..:.|..||:.|.|:|..|..:|.|  ..|.....:||:|.:.....:.||:.| ..|
 Frog   531 LDQLRSLTQIDLEGNPWDCTCDLVALKLWLEKLSEGIVMKEVKCETPVQFANIELRSLKNE-ILC 594

  Fly   525 SWDELRMKLSGE--CRMDSDCPAMCHCEGTTVDCTGRGLKEIPRDIPLHTTELLLN--------- 578
            .      ||..:  .:..|..||:..       .|..|..:.|...|:..:.|:|:         
 Frog   595 P------KLINKPPTQYTSPVPAVTF-------TTPLGPIKSPPGGPVPLSILILSILVVLILTV 646

  Fly   579 ------------DNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKI 631
                        .|:...:..:|:..:....::|:|:::....::.:.....:...:      .|
 Frog   647 FVAFCLLVFVLRRNKKPTVKHEGIGNQECSSMQLQLRKHDQKALKMDGISAETFFPQ------TI 705

  Fly   632 KEISNKMFLGL-----------HQLKTL---NLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCN 682
            :::|.....|:           ||.:||   ||.:.:...:...|.:.|:::..|:......:.|
 Frog   706 EQMSKSHTCGIKDSEVGFSFSDHQGQTLALRNLTEKEKDLLHGDSRKRLSTIDELDEFFPGRDSN 770

  Fly   683 CHLAWFAEWLRKKSLNG---GAARCGAPSKVRDVQIKDL----PHSEFKCSSENSE 731
            ..:..|.|  .||..|.   .......|.|::|.:.|..    .||:.......||
 Frog   771 LFIQNFLE--SKKEYNSIGVSGFEIHYPEKLQDKKNKKSLIGGNHSKIVVEQRKSE 824

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sliNP_001261017.1 LRRNT 73..103 CDD:214470 8/33 (24%)
leucine-rich repeat 83..104 CDD:275380 4/27 (15%)
LRR_8 102..160 CDD:290566 22/57 (39%)
leucine-rich repeat 105..125 CDD:275380 6/19 (32%)
LRR_RI <119..259 CDD:238064 51/163 (31%)
leucine-rich repeat 126..149 CDD:275380 9/22 (41%)
LRR_8 149..208 CDD:290566 18/58 (31%)
leucine-rich repeat 150..173 CDD:275380 8/22 (36%)
leucine-rich repeat 174..197 CDD:275380 5/22 (23%)
LRR_8 197..256 CDD:290566 26/82 (32%)
leucine-rich repeat 198..221 CDD:275380 9/22 (41%)
leucine-rich repeat 222..245 CDD:275380 11/46 (24%)
leucine-rich repeat 246..371 CDD:275380 41/203 (20%)
LRRCT 254..303 CDD:214507 16/58 (28%)
LRRNT 319..350 CDD:214470 11/38 (29%)
LRR_8 349..406 CDD:290566 15/56 (27%)
LRR_4 371..411 CDD:289563 12/39 (31%)
leucine-rich repeat 372..395 CDD:275380 5/22 (23%)
leucine-rich repeat 396..415 CDD:275380 7/18 (39%)
leucine-rich repeat 420..443 CDD:275380 8/22 (36%)
leucine-rich repeat 444..465 CDD:275380 9/44 (20%)
leucine-rich repeat 468..480 CDD:275378 3/11 (27%)
LRRCT 476..525 CDD:214507 15/50 (30%)
leucine-rich repeat 484..545 CDD:275380 15/64 (23%)
LRRNT 542..574 CDD:214470 6/31 (19%)
leucine-rich repeat 552..570 CDD:275380 3/17 (18%)
leucine-rich repeat 572..596 CDD:275380 4/44 (9%)
LRR_RI <574..>678 CDD:238064 18/138 (13%)
LRR_8 595..655 CDD:290566 11/73 (15%)
leucine-rich repeat 597..620 CDD:275380 2/22 (9%)
leucine-rich repeat 621..644 CDD:275380 3/33 (9%)
leucine-rich repeat 645..668 CDD:275380 6/25 (24%)
leucine-rich repeat 669..756 CDD:275380 15/70 (21%)
LRRCT 677..726 CDD:214507 12/55 (22%)
LRRNT 739..770 CDD:214470
leucine-rich repeat 757..791 CDD:275380
LRR_4 770..807 CDD:289563
LRR_8 790..850 CDD:290566
LRR_4 791..830 CDD:289563
leucine-rich repeat 792..815 CDD:275380
LRR_4 814..863 CDD:289563
leucine-rich repeat 816..839 CDD:275380
leucine-rich repeat 840..861 CDD:275380
LRRCT 872..920 CDD:214507
EGF 935..966 CDD:278437
EGF_CA 971..1007 CDD:238011
EGF_CA 1009..1045 CDD:238011
EGF_CA 1055..1086 CDD:238011
EGF_CA 1088..1124 CDD:238011
Laminin_G_1 1204..1335 CDD:278483
CT 1435..1504 CDD:214482
slitrk4XP_004916941.2 internalin_A <30..>268 CDD:380193 76/256 (30%)
leucine-rich repeat 78..99 CDD:275380 6/20 (30%)
LRR_8 102..158 CDD:404697 27/79 (34%)
leucine-rich repeat 102..123 CDD:275380 9/20 (45%)
leucine-rich repeat 124..147 CDD:275380 13/46 (28%)
LRR_8 147..205 CDD:404697 20/57 (35%)
leucine-rich repeat 148..171 CDD:275380 9/22 (41%)
leucine-rich repeat 172..194 CDD:275380 10/21 (48%)
leucine-rich repeat 195..219 CDD:275380 1/23 (4%)
leucine-rich repeat 220..312 CDD:275380 20/99 (20%)
leucine-rich repeat 313..416 CDD:275380 21/102 (21%)
leucine-rich repeat 372..392 CDD:275380 5/19 (26%)
PPP1R42 373..546 CDD:411060 44/172 (26%)
LRR_8 416..473 CDD:404697 19/56 (34%)
leucine-rich repeat 417..440 CDD:275380 5/22 (23%)
leucine-rich repeat 441..464 CDD:275380 10/22 (45%)
leucine-rich repeat 465..486 CDD:275380 8/20 (40%)
leucine-rich repeat 489..510 CDD:275380 7/20 (35%)
leucine-rich repeat 512..536 CDD:275380 2/23 (9%)
TPKR_C2 545..>577 CDD:417692 11/31 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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