DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sli and lrrc3

DIOPT Version :9

Sequence 1:NP_001261017.1 Gene:sli / 36746 FlyBaseID:FBgn0264089 Length:2157 Species:Drosophila melanogaster
Sequence 2:NP_001107114.1 Gene:lrrc3 / 100001372 ZFINID:ZDB-GENE-080327-13 Length:266 Species:Danio rerio


Alignment Length:197 Identity:56/197 - (28%)
Similarity:86/197 - (43%) Gaps:51/197 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   543 CPAMCHCEG----TTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLPHLVKLELK 603
            ||..|||..    |.|.|:.|.|:|||.|:|..|..|.|:.|.:.:|.:.. |..||.|.:|:|.
Zfish    39 CPKSCHCSERNSLTVVQCSSRNLEEIPPDLPHDTVSLQLSSNHITKIPNQA-FKNLPWLQELDLS 102

  Fly   604 RNQLTGIEPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKTLNLYDNQISCVMPGSFEHLNS 668
            ||.:..::..||:|.|                       ..|:||:|..|.:..|...:|..|::
Zfish   103 RNAIETVDAGAFKGVS-----------------------ESLRTLDLSHNHMQGVPKEAFARLHA 144

  Fly   669 LTSLNLASNPFNCNCHLAWFAEWLRKKSLNGGAARCGAPSKVRDVQIKDLPHSEFKCSSENSEGC 733
              .::|::||::|.|.|   .|.||:..|:        |..|.:|          .|.:.:.|..
Zfish   145 --KISLSNNPWHCECTL---QEVLRELRLD--------PETVNEV----------SCHTSDQEKY 186

  Fly   734 LG 735
            .|
Zfish   187 AG 188

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sliNP_001261017.1 LRRNT 73..103 CDD:214470
leucine-rich repeat 83..104 CDD:275380
LRR_8 102..160 CDD:290566
leucine-rich repeat 105..125 CDD:275380
LRR_RI <119..259 CDD:238064
leucine-rich repeat 126..149 CDD:275380
LRR_8 149..208 CDD:290566
leucine-rich repeat 150..173 CDD:275380
leucine-rich repeat 174..197 CDD:275380
LRR_8 197..256 CDD:290566
leucine-rich repeat 198..221 CDD:275380
leucine-rich repeat 222..245 CDD:275380
leucine-rich repeat 246..371 CDD:275380
LRRCT 254..303 CDD:214507
LRRNT 319..350 CDD:214470
LRR_8 349..406 CDD:290566
LRR_4 371..411 CDD:289563
leucine-rich repeat 372..395 CDD:275380
leucine-rich repeat 396..415 CDD:275380
leucine-rich repeat 420..443 CDD:275380
leucine-rich repeat 444..465 CDD:275380
leucine-rich repeat 468..480 CDD:275378
LRRCT 476..525 CDD:214507
leucine-rich repeat 484..545 CDD:275380 1/1 (100%)
LRRNT 542..574 CDD:214470 16/34 (47%)
leucine-rich repeat 552..570 CDD:275380 9/17 (53%)
leucine-rich repeat 572..596 CDD:275380 7/23 (30%)
LRR_RI <574..>678 CDD:238064 25/103 (24%)
LRR_8 595..655 CDD:290566 15/59 (25%)
leucine-rich repeat 597..620 CDD:275380 8/22 (36%)
leucine-rich repeat 621..644 CDD:275380 0/22 (0%)
leucine-rich repeat 645..668 CDD:275380 8/22 (36%)
leucine-rich repeat 669..756 CDD:275380 16/67 (24%)
LRRCT 677..726 CDD:214507 12/48 (25%)
LRRNT 739..770 CDD:214470
leucine-rich repeat 757..791 CDD:275380
LRR_4 770..807 CDD:289563
LRR_8 790..850 CDD:290566
LRR_4 791..830 CDD:289563
leucine-rich repeat 792..815 CDD:275380
LRR_4 814..863 CDD:289563
leucine-rich repeat 816..839 CDD:275380
leucine-rich repeat 840..861 CDD:275380
LRRCT 872..920 CDD:214507
EGF 935..966 CDD:278437
EGF_CA 971..1007 CDD:238011
EGF_CA 1009..1045 CDD:238011
EGF_CA 1055..1086 CDD:238011
EGF_CA 1088..1124 CDD:238011
Laminin_G_1 1204..1335 CDD:278483
CT 1435..1504 CDD:214482
lrrc3NP_001107114.1 LRR_RI <14..161 CDD:238064 46/150 (31%)
LRRNT 38..72 CDD:214470 15/32 (47%)
leucine-rich repeat 51..74 CDD:275378 11/22 (50%)
LRR 1 71..92 6/21 (29%)
LRR_8 74..131 CDD:290566 21/80 (26%)
LRR_4 74..111 CDD:289563 12/37 (32%)
leucine-rich repeat 75..95 CDD:275378 6/20 (30%)
LRR 2 95..116 7/20 (35%)
leucine-rich repeat 96..120 CDD:275378 9/46 (20%)
LRR 3 120..141 7/20 (35%)
leucine-rich repeat 121..144 CDD:275378 8/22 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4237
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.