Protein Alignment CG8249 and HXT5

DIOPT Version :10

• Sequence 1: NP_611060.2
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_011964.1
• Gene: HXT5 / 856496
• SGDID: S000001138
• Length: 592
• Species: Saccharomyces cerevisiae
• Alignment Length: 533
• Identity: 124/533 - (23%)
• Similarity: 225/533 - (42%)
• Gaps: 70/533 - (13%)

  Fly    12 GSESNGKQARIVSGLDRLLKTPPPGEQTRAVRRQV------------IAVILANVGVFSTGMTLA 64
            |...|..||:.||..  :....||.::...::::|            :.|.:..:.|...|....
Yeast    39 GYNDNLAQAKPVSSY--ISHEGPPKDELEELQKEVDKQLEKKSKSDLLFVSVCCLMVAFGGFVFG 101

  Fly    65 MPTATLHQLKDTTE------------PVHLNDSQASWFASVNALSAPIGGLLSGFLLDRIGRKKS 117
            ..|.|:......|:            ..:|:|.:.....|:..:...|||::...|.|..|||..
Yeast   102 WDTGTISGFVRQTDFIRRFGSTRANGTTYLSDVRTGLMVSIFNIGCAIGGIVLSKLGDMYGRKIG 166

  Fly   118 LIVLNVLIILAWILLATPSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLI 182
            |:.:.|:..:..|:.....:.     ::|..:.|.:.|:|:|..:....:..:|:|..:.||:|:
Yeast   167 LMTVVVIYSIGIIIQIASIDK-----WYQYFIGRIISGLGVGGITVLAPMLISEVSPKQLRGTLV 226

  Fly   183 LGTSISVAGGITILYGIGYCIR---------DDFRLIALICCGYQLVALLCVLPLPESHCWLLSK 238
            ....:.:..||.    :|||..         ..:|:...:|..:.:..::.:..:|||..:|:..
Yeast   227 SCYQLMITFGIF----LGYCTNFGTKNYSNSVQWRVPLGLCFAWSIFMIVGMTFVPESPRYLVEV 287

  Fly   239 KRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTAVKESFWRNL--HEPEVYKPLV 301
            .::.||||||   ...||:.| ..|.|..|.:..|.|::....|...| |..|  .:|::::..:
Yeast   288 GKIEEAKRSL---ARANKTTE-DSPLVTLEMENYQSSIEAERLAGSAS-WGELVTGKPQMFRRTL 347

  Fly   302 ILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLARLITTCPMGYILEWWGRRRAG 366
            :.|.:.:.|||||......:...|.|..|:| |.|..|:::|:...::|....|.::.:|||...
Yeast   348 MGMMIQSLQQLTGDNYFFYYGTTIFQAVGLE-DSFETAIVLGVVNFVSTFFSLYTVDRFGRRNCL 411

  Fly   367 IISTLGMSVCMFLLAGHSQIEILKEVPYLPVVAIVG--FIVLSTLGLY-------TLPFFMISEL 422
            :...:||..|..:.|......:.......|.....|  .||.:...::       .:.:.:|||.
Yeast   412 LWGCVGMICCYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPVAYVLISES 476

  Fly   423 FPQKVRGPASGLTVAV----GMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPE 483
            :|.:|||.|..:..|.    |..|||........|..|.|    ::..|.| :||..:|:..:||
Yeast   477 YPLRVRGKAMSIASACNWIWGFLISFFTPFITSAINFYYG----YVFMGCM-VFAYFYVFFFVPE 536

  Fly   484 TRRRTLLEIEEQF 496
            |:..||.|:.|.:
Yeast   537 TKGLTLEEVNEMY 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_611060.2	MFS_GLUT6_8_Class3_like	46..491	CDD:340916	114/492 (23%)
HXT5	NP_011964.1	Sugar_tr	89..549	CDD:395036	114/479 (24%)