Protein Alignment CG8249 and HXT1

DIOPT Version :10

• Sequence 1: NP_611060.2
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_011962.1
• Gene: HXT1 / 856494
• SGDID: S000001136
• Length: 570
• Species: Saccharomyces cerevisiae
• Alignment Length: 587
• Identity: 124/587 - (21%)
• Similarity: 233/587 - (39%)
• Gaps: 105/587 - (17%)

  Fly    10 QNGSESNGKQARIVSGLDRLLKTP---------------------PPGEQTRAVRRQVIAVILAN 53
            |..:.||..:  :.||..:.:.||                     ||    ...:...:.|.:..
Yeast    11 QKSNSSNSYE--LESGRSKAMNTPEGKNESFHDNLSESQVQPAVAPP----NTGKGVYVTVSICC 69

  Fly    54 VGVFSTGMTLAMPTATLHQLKDTTEPV------------HLNDSQASWFASVNALSAPIGGLLSG 106
            |.|...|......|.|:......|:.:            :|:..:.....|:..:...|||::..
Yeast    70 VMVAFGGFIFGWDTGTISGFVAQTDFLRRFGMKHHDGSHYLSKVRTGLIVSIFNIGCAIGGIVLA 134

  Fly   107 FLLDRIGRKKSLIVLNVLIILAWIL-LATPSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAA 170
            .|.|..||:..|||:.|:..:..|: :|:.::      ::|..:.|.:.|:|:|..:....:..:
Yeast   135 KLGDMYGRRIGLIVVVVIYTIGIIIQIASINK------WYQYFIGRIISGLGVGGITVLSPMLIS 193

  Fly   171 EISVPKTRGSLILGTSISVAGGITILYGIGYCIR---------DDFRLIALICCGYQLVALLCVL 226
            |::..:.||:|:....:.:..||.    :|||..         ..:|:...:|..:.|..:..::
Yeast   194 EVAPSEMRGTLVSCYQVMITLGIF----LGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMM 254

  Fly   227 PLPESHCWLLSKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTAVKESFWRNL 291
            .:|||..:|:...|:.||:.||   ...||... .||.:..|.:.::.|:::...|...| |..|
Yeast   255 FVPESPRYLVEAGRIDEARASL---AKVNKCPP-DHPYIQYELETIEASVEEMRAAGTAS-WGEL 314

  Fly   292 H--EPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLARLITTCPMG 354
            .  :|.:::..::.:.:.:.|||||......:...:.|..|:. |.|..:::.|:....:||...
Yeast   315 FTGKPAMFQRTMMGIMIQSLQQLTGDNYFFYYGTIVFQAVGLS-DSFETSIVFGVVNFFSTCCSL 378

  Fly   355 YILEWWGRRRAGIISTLGMSVCMFLLAGHSQIEILKEVPYLPVVAIVG--FIVLSTLGLY----- 412
            |.::.:|||...:...:||..|..:.|......:.......|.....|  .||.:...::
Yeast   379 YTVDRFGRRNCLMWGAVGMVCCYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATT 443

  Fly   413 --TLPFFMISELFPQKVRGPASGLTVAV----GMFISFVVLKTYPGIKEYLGMSNCFIIFGVMAL 471
              .:.:.:|||.||.:|:.....:..|.    |..|||........|..|.|    ::..|.| :
Yeast   444 WAPIAYVVISECFPLRVKSKCMSIASAANWIWGFLISFFTPFITGAINFYYG----YVFMGCM-V 503

  Fly   472 FALIFVYLALPETRRRTLLEIEEQFRSG--------------RSKSQNQADVE------MKEVFV 516
            ||..:|:..:|||:..:|.|:.:.:..|              |....|..|:.      .|.:|.
Yeast   504 FAYFYVFFFVPETKGLSLEEVNDMYAEGVLPWKSASWVPVSKRGADYNADDLMHDDQPFYKSLFS 568

  Fly   517 RK 518
            ||
Yeast   569 RK 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_611060.2	MFS_GLUT6_8_Class3_like	46..491	CDD:340916	106/481 (22%)
HXT1	NP_011962.1	Sugar_tr	68..528	CDD:395036	106/480 (22%)