Protein Alignment CG8249 and AZR1

DIOPT Version :9

• Sequence 1: NP_001246349.1
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_011740.3
• Gene: AZR1 / 853139
• SGDID: S000003456
• Length: 613
• Species: Saccharomyces cerevisiae
• Alignment Length: 624
• Identity: 112/624 - (17%)
• Similarity: 198/624 - (31%)
• Gaps: 222/624 - (35%)

  Fly    39 TRAVRRQVIAVILAN---------------VGVFSTGMTLAMPTATLHQLKDTTEPVHLNDSQAS 88
            |::..:|.::|:|.:               ..:.:..::|.:....:..:....|.|      |.
Yeast    38 TQSTSKQNVSVVLEDNASESNELPKGFILYASLIALALSLFLAALDIMIVSTIIEEV------AK 96

  Fly    89 WFASVNALSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFWQLIVSRFM 153
            .|.|.    :.||.|.:|:.|.           |.|:.|.|..:|||....:...|
Yeast    97 QFGSY----SEIGWLFTGYSLP-----------NALLALIWGRIATPIGFKETMLF--------- 137

  Fly   154 LGVGMGLASAPPGVYAAEISVPKTRGSLI--LGTSISVAGGITILYGIGYC-------------I 203
                        .:...||      ||||  |..|:|:..|..::.|:|.|             :
Yeast   138 ------------AIVIFEI------GSLISALANSMSMLIGGRVIAGVGGCGIQSLSFVIGSTLV 184

  Fly   204 RDDFR--LIALICCGYQLVALL----------------CV---LPLPESHCWLLSKKRVTEAKRS 247
            .:..|  |||::.|.:.:.:::                |.   ||:.....:|
Yeast   185 EESQRGILIAVLSCSFAIASVVGPFLGGVFTSSVTWRWCFYVNLPIGGLAFFL------------ 237

  Fly   248 LNYFRGFNKSDEITHPQVLEEFQLLQKSLQQ--RNTAV---------KESFWRNLHEPEVYKPLV 301
               |..|......|..:.::..:.......:  ||.|.         |.:.||     :.:..|:
Yeast   238 ---FLFFYNPGLSTFQETMDNIRKFPSQFIEIVRNVAYHLLKIKGFSKLNGWR-----KPFMELI 294

  Fly   302 ILMSLFAFQQLTGIFVVIVFAVQIS------QEAGIEIDPFMCAVLIGLARL----------ITT 350
            .:..:..|...:..|..|:.|....      ..|.|.|...:..||:.||.:          |..
Yeast   295 FMYDIIEFVFCSAGFTCILLAFTFGGNRYAWNSASIIILFIIGIVLVVLAGIYDFLVFPKFNIVK 359

  Fly   351 CPMGY--ILEWWGRRRAGIISTLGMSVCMFL-LAGH-SQIEILKEVPYLP--------------V 397
            ....|  ::.|...::.||.:   :::.:|| .||: ||...:  |.|..              |
Yeast   360 ATPHYQPLMSWTNIKKPGIFT---VNIALFLTCAGYISQFTYI--VQYFQLIYNDSAWRAAVHLV 419

  Fly   398 VAIVGFIVLSTL-GLYT------LPFFMISELFPQKVRGPAS------------GLTVAVGM--- 440
            ..|:..:|.:.| |..|      .|..:||.:|.....|..:            ||.:..|:
Yeast   420 ACIISTVVTAILCGAITDKTRQIKPIIVISSIFGVVGAGILTLLNNNANNSAHIGLLILPGVAFG 484

  Fly   441 ------------------------FISFVVLKTY-PGIKEYLG--MSNCFIIFGVMALFALIFVY 478
                                    |:|.....|: ..:.:.||  :||  .:|...|:..|....
Yeast   485 GLAQSSMLASQIQLDKKSPTFRSDFVSITTFNTFCKNLGQALGGVISN--TVFSAAAIKKLTKAN 547

  Fly   479 LALPE--TRRRTLLEIEEQFRSGRSKSQNQADVEMKEVF 515
            :.||:  |....::..:..|....||..|.....:.:||
Yeast   548 IQLPDGTTVDNLVIYRQTNFDGSHSKLGNIISESLTDVF 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	101/574 (18%)
		Sugar_tr	60..496	CDD:278511	102/567 (18%)
AZR1	NP_011740.3	MFS_Azr1_MDR_like	83..540	CDD:341045	96/531 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900