Protein Alignment CG8249 and ITR1

DIOPT Version :9

• Sequence 1: NP_001246349.1
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_010785.1
• Gene: ITR1 / 852108
• SGDID: S000002905
• Length: 584
• Species: Saccharomyces cerevisiae
• Alignment Length: 502
• Identity: 118/502 - (23%)
• Similarity: 220/502 - (43%)
• Gaps: 43/502 - (8%)

  Fly    46 VIAVILANVGVFSTGMTLAMPTATLHQLKDTTEPVHLNDSQASWFASVNALSAPIGGLLSGFLLD 110
            :....:|::..|..|......::.|..:....:...|...:.....:..:|.|.|..:.:|...|
Yeast    87 ITLTFVASISGFMFGYDTGYISSALISIGTDLDHKVLTYGEKEIVTAATSLGALITSIFAGTAAD 151

  Fly   111 RIGRKKSLIVLNVLIILAWILLATPSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVP 175
            ..|||:.|:..|::.::..||..:...      |||:.|.|.::|.|:|:.|....::.:||:..
Yeast   152 IFGRKRCLMGSNLMFVIGAILQVSAHT------FWQMAVGRLIMGFGVGIGSLIAPLFISEIAPK 210

  Fly   176 KTRGSLILGTSISVAGGITILYGIG----YCIRDDFRLIALICCGYQLVALLCVLPLPESHCWLL 236
            ..||.|.:..|:.:.||..:.||.|    | :.:.:|::..:......|...|:..||::..:.:
Yeast   211 MIRGRLTVINSLWLTGGQLVAYGCGAGLNY-VNNGWRILVGLSLIPTAVQFTCLCFLPDTPRYYV 274

  Fly   237 SK---KRVTEA-KRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTAVKESFWRNLHE---- 293
            .|   .|.||. |||..     :.|:||...:| ||...|.:|:..:|  |.|..|..:.|
Yeast   275 MKGDLARATEVLKRSYT-----DTSEEIIERKV-EELVTLNQSIPGKN--VPEKVWNTIKELHTV 331

  Fly   294 PEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLARLITTCPMGYILE 358
            |...:.|:|...|.|.||.||...::.|:..|.:..|.: :....::::.....|.|....:.::
Yeast   332 PSNLRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFK-NSSAVSIIVSGTNFIFTLVAFFSID 395

  Fly   359 WWGRRRAGIISTLGMSVCMFL--LAGH-------SQIEILKEVPY-----LPVVAIVGFIVLSTL 409
            ..|||...:|...||::.:.:  :|.|       ..:.::....:     :.:|.|:.|.....|
Yeast   396 KIGRRTILLIGLPGMTMALVVCSIAFHFLGIKFDGAVAVVVSSGFSSWGIVIIVFIIVFAAFYAL 460

  Fly   410 GLYTLPFFMISELFPQKVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFAL 474
            |:.|:| :..||||||.|||..:....|.....|.|:..|:..:.:.:..:..|..|..::..:.
Yeast   461 GIGTVP-WQQSELFPQNVRGIGTSYATATNWAGSLVIASTFLTMLQNITPAGTFAFFAGLSCLST 524

  Fly   475 IFVYLALPETRRRTLLEIEEQFRSGRSKSQNQADVEMKEVFVRKPEE 521
            ||.|...||.....|.|::...:.|.:...::|..:.::..|.:..|
Yeast   525 IFCYFCYPELSGLELEEVQTILKDGFNIKASKALAKKRKQQVARVHE 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	109/455 (24%)
		Sugar_tr	60..496	CDD:278511	112/461 (24%)
ITR1	NP_010785.1	MFS_HMIT_like	92..533	CDD:340918	110/457 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342433
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2521
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.690