DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and HXT7

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_010629.3	Gene:	HXT7 / 851943	SGDID:	S000002750	Length:	570	Species:	Saccharomyces cerevisiae

Alignment Length:	455	Identity:	106/455 - (23%)
Similarity:	197/455 - (43%)	Gaps:	56/455 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 KDTTEPVHLNDSQASWFASVNALSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWIL-LATPSE 137
            ||.|.  :|:..:.....|:..:...|||::...|.|..|||..|||:.|:.|:..|: :|:.::
Yeast   104 KDGTN--YLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINK 166

  Fly   138 SDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLILGTSISVAGGITILYGIGYC 202
                  ::|..:.|.:.|:|:|..:....:..:|:|....||:|:....:.:..||.    :|||
Yeast   167 ------WYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIF----LGYC 221

  Fly   203 IR---------DDFRLIALICCGYQLVALLCVLPLPESHCWLLSKKRVTEAKRSLNYFRGFNKSD 258
            ..         ..:|:...:|..:.|..:..:..:|||..:|....::.|||||:    ..:...
Yeast   222 TNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSI----AVSNKV 282

  Fly   259 EITHPQVLEEFQLLQKSLQQRNTAVKESFWRNL--HEPEVYKPLVILMSLFAFQQLTGIFVVIVF 321
            .:..|.||.|.:.:...::....|...| |..|  .:.:|.:.|::...:.:.|||||......:
Yeast   283 AVDDPSVLAEVEAVLAGVEAEKLAGNAS-WGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYY 346

  Fly   322 AVQISQEAGIEIDPFMCAVLIGLARLITTCPMGYILEWWGRRRAGIISTLGMSVCMFLLAGHSQI 386
            ...|.:..|:. |.|..::::|:....:|....|::|.:|||...:.....|:.||.:.|.....
Yeast   347 GTTIFKAVGLS-DSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVT 410

  Fly   387 EILKEVPYLPVVAIVG--FIVLSTLGLY-------TLPFFMISELFPQKVRGPASGLTVA----- 437
            .:.......|.....|  .||.:...::       .:|:.::||.||.:|:..|..:..|
Yeast   411 RLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLW 475

  Fly   438 ---VGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQFRSG 499
               :|.|..|:.    ..|..|.|    ::..|.: :|...:|.|.:|||:..||.|:...:..|
Yeast   476 GFLIGFFTPFIT----GAINFYYG----YVFMGCL-VFMFFYVLLVVPETKGLTLEEVNTMWEEG 531

Fly 500 499
Yeast 532 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	98/433 (23%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	105/450 (23%)
HXT7	NP_010629.3	Sugar_tr	68..528	CDD:395036	105/450 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342982
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.740