DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and SNF3

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_010087.1	Gene:	SNF3 / 851333	SGDID:	S000002353	Length:	884	Species:	Saccharomyces cerevisiae

Alignment Length:	537	Identity:	128/537 - (23%)
Similarity:	236/537 - (43%)	Gaps:	82/537 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NLNQNGSESNGKQARI----VSGLD--RLLKTPPPGEQTRAVRRQVIAVILANVGVF----STGM 61
            :|.:..|:.......:    :|.:|  .:|.:.||  |.:::...:...:...||.|    .||:
Yeast    55 SLQRQNSDRQSNMTSVFTDDISTIDDNSILFSEPP--QKQSMMMSICVGVFVAVGGFLFGYDTGL 117

  Fly    62 TLAMPTATLHQLKDTTEPVHLNDS----QASWFASVNALSAPIGGLLSGFLLDRIGRKKSLIVLN 122
            ..::  .:::.:|....|.|  ||    |.|...|..:|....|.|.:.|:.|..|||.::|...
Yeast   118 INSI--TSMNYVKSHVAPNH--DSFTAQQMSILVSFLSLGTFFGALTAPFISDSYGRKPTIIFST 178

  Fly   123 VLIILAWILLATPSESDQNAF------FWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSL 181
            :.|.           |..|:.      ...|||.|.:.|:|:|..||...:|.||.:....||::
Yeast   179 IFIF-----------SIGNSLQVGAGGITLLIVGRVISGIGIGAISAVVPLYQAEATHKSLRGAI 232

  Fly   182 ILGTSISVAGGITILYGI--GYCIRDD---FRLIALICCGYQLV--ALLCV--LPLPESHCWLLS 237
            |.....::..|:.:...:  |...|:|   :|    |..|.|.|  :.|.:  ..||||..:.:.
Yeast   233 ISTYQWAITWGLLVSSAVSQGTHARNDASSYR----IPIGLQYVWSSFLAIGMFFLPESPRYYVL 293

  Fly   238 KKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQR----NTAVKESFWRNLHEPEVYK 298
            |.::.||.:||::.||....|.    .:|||...::.:....    ::...:.|..:...|:...
Yeast   294 KDKLDEAAKSLSFLRGVPVHDS----GLLEELVEIKATYDYEASFGSSNFIDCFISSKSRPKQTL 354

  Fly   299 PLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLARLITTCPMGYILEWWGRR 363
            .:...::|.||||.:||..:..:.|....:.|:. :.::.:.:.....::...|..:.:|::|||
Yeast   355 RMFTGIALQAFQQFSGINFIFYYGVNFFNKTGVS-NSYLVSFITYAVNVVFNVPGLFFVEFFGRR 418

  Fly   364 RAGIISTLGMSVCMFLLA--GHSQIEILKEVPYLPVVAIVGFIVL------STLGLYTLPFFMIS 420
            :..::..:.|::..|::|  |.|    ||.|....|  ::.||.|      :|.|  .:.:.:.:
Yeast   419 KVLVVGGVIMTIANFIVAIVGCS----LKTVAAAKV--MIAFICLFIAAFSATWG--GVVWVISA 475

  Fly   421 ELFPQKVRGPASGLTVAVGMFISFVVLKTYPGIKE------YLGMSNCFIIFGVMALFALIFVYL 479
            ||:|..||...:.:..|....::|:.....|.|.:      .|| :..|.|:|.:....:|.|||
Yeast   476 ELYPLGVRSKCTAICAAANWLVNFICALITPYIVDTGSHTSSLG-AKIFFIWGSLNAMGVIVVYL 539

  Fly   480 ALPETRRRTLLEIEEQF 496
            .:.||:..||.||:|.:
Yeast   540 TVYETKGLTLEEIDELY 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	111/470 (24%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	116/472 (25%)
SNF3	NP_010087.1	MFS_HXT	99..556	CDD:340914	120/489 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342635
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.740