DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8249 and ERDL6

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_177658.1	Gene:	ERDL6 / 843859	AraportID:	AT1G75220	Length:	487	Species:	Arabidopsis thaliana

Alignment Length:	470	Identity:	122/470 - (25%)
Similarity:	220/470 - (46%)	Gaps:	55/470 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VILANVGVFSTGMTLAMPTATLHQLKDTTEPVHLNDSQASWFASVNALSAPIGGLLSGFLLDRIG 113
            |::..:|....|.|....:.|...:   |:.:.|..|:.|.|.|::.:.|.:|.:.||.:.:.||
plant    52 VLIVALGPIQFGFTCGYSSPTQAAI---TKDLGLTVSEYSVFGSLSNVGAMVGAIASGQIAEYIG 113

  Fly   114 RKKSLIVLNVLIILAWILLATPSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTR 178
            ||.||::..:..|:.|:.:   |.:...:|   |.:.|.:.|.|:|:.|....||.|||:....|
plant   114 RKGSLMIAAIPNIIGWLCI---SFAKDTSF---LYMGRLLEGFGVGIISYTVPVYIAEIAPQNMR 172

  Fly   179 GSLILGTSISVAGGITILYGIGYCIRDDFRLIALICCGYQLVALLCVLP----------LPESHC 233
            |.|.....:||..||.:.|.:|..:            .::::|:|.:||          :|||..
plant   173 GGLGSVNQLSVTIGIMLAYLLGLFV------------PWRILAVLGILPCTLLIPGLFFIPESPR 225

  Fly   234 WLLSKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTAVKESFWRNLHEPEVYK 298
            ||.......|.:.||...|||.....:.    :.|.:....|..:|||.    .:.:|.....|.
plant   226 WLAKMGMTDEFETSLQVLRGFETDITVE----VNEIKRSVASSTKRNTV----RFVDLKRRRYYF 282

  Fly   299 PLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLARLITTCPMGYILEWWGRR 363
            ||::.:.|...|||.||..|:.::..|.:.||: .........:|..:::.|....::::..|||
plant   283 PLMVGIGLLVLQQLGGINGVLFYSSTIFESAGV-TSSNAATFGVGAIQVVATAISTWLVDKAGRR 346

  Fly   364 RAGIISTLGMSVCMFLLAGHSQIEILKE-----------VPYLPVVAIVGFIVLSTLGLYTLPFF 417
            ....||::||::.:.::|.   ...|||           :..|.||.:|..:|..:||:..:|:.
plant   347 LLLTISSVGMTISLVIVAA---AFYLKEFVSPDSDMYSWLSILSVVGVVAMVVFFSLGMGPIPWL 408

  Fly   418 MISELFPQKVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALP 482
            ::||:.|..::|.|..:......|.|:::..|...:..: .....|.::|::..|.::||.|.:|
plant   409 IMSEILPVNIKGLAGSIATLANWFFSWLITMTANLLLAW-SSGGTFTLYGLVCAFTVVFVTLWVP 472

  Fly   483 ETRRRTLLEIEEQFR 497
            ||:.:||.|::..||
plant   473 ETKGKTLEELQSLFR 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	113/450 (25%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	118/456 (26%)
ERDL6	NP_177658.1	MFS_GLUT6_8_Class3_like	49..481	CDD:340916	119/462 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920