DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8249 and ESL1

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_849618.1	Gene:	ESL1 / 837413	AraportID:	AT1G08920	Length:	477	Species:	Arabidopsis thaliana

Alignment Length:	480	Identity:	128/480 - (26%)
Similarity:	212/480 - (44%)	Gaps:	68/480 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 QVIAVILANV-----GVF----STGMTLAMPTATLHQLKDTTEPVHLNDSQASWFASVNALSAPI 100
            ::.||:|.:.     |.|    :.|.:....|..::.|       .|:.:|.|.|.|:......|
plant    27 RITAVVLFSTFVSVCGSFCFGCAAGYSSVAQTGIINDL-------GLSVAQYSMFGSIMTFGGMI 84

  Fly   101 GGLLSGFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFWQLIVSRFMLGVGMGLASAPP 165
            |.:.||.:.|.:|||.::....:..|..|:.:|...:|     .| |.:.|...|..:||.|...
plant    85 GAIFSGKVADLMGRKGTMWFAQIFCIFGWVAVALAKDS-----MW-LDIGRLSTGFAVGLLSYVI 143

  Fly   166 GVYAAEISVPKTRGSLILGTSISVAGGITILYGIGYCIR-DDFRLIALICCGYQLVALLCVLPLP 229
            .||.|||:....||:.:....:..:.|:::.|.||..:. .:..||.||.|..|:|.|..:   |
plant   144 PVYIAEITPKHVRGAFVFANQLMQSCGLSLFYVIGNFVHWRNLALIGLIPCALQVVTLFFI---P 205

  Fly   230 ESHCWLLSKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSL----QQRNTAVKESFWRN 290
            ||...|.......|.:.||...||    |:   ..:.||...:::::    :...:.|.:.|.|.
plant   206 ESPRLLGKWGHEKECRASLQSLRG----DD---ADISEEANTIKETMILFDEGPKSRVMDLFQRR 263

  Fly   291 LHEPEVYKPLVIL-MSLFAFQQLTGIFVVIVFAVQISQEAGI--EIDPFMCAVLIGLARLITTCP 352
                  |.|.|:: :.|...|||:|...::.:...:..:.|.  .|...:.||:     :|....
plant   264 ------YAPSVVIGVGLMLLQQLSGSSGLMYYVGSVFDKGGFPSSIGSMILAVI-----MIPKAL 317

  Fly   353 MGYIL-EWWGRRRAGII-------STLGMSVCMF-LLAGHS----QIEILKEV-PYLPVVAIVGF 403
            :|.|| |..|||...::       ||.||  |.| ||...|    ...:|.|: |....:.:|||
plant   318 LGLILVEKMGRRPLLLMNDLYLQASTGGM--CFFSLLLSFSFCFRSYGMLDELTPIFTCIGVVGF 380

  Fly   404 IVLSTLGLYTLPFFMISELFPQKVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGV 468
            |....:|:..||:.::||:||..|:..|..|.........::|...|..:.|: ..|..|:||..
plant   381 ISSFAVGMGGLPWIIMSEIFPMNVKVSAGTLVTLANWSFGWIVAFAYNFMLEW-NASGTFLIFFT 444

  Fly   469 MALFALIFVYLALPETRRRTLLEIE 493
            :....::|:|..:|||:.|||.:|:
plant   445 ICGAGIVFIYAMVPETKGRTLEDIQ 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	119/460 (26%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	123/456 (27%)
ESL1	NP_849618.1	Sugar_tr	36..469	CDD:278511	124/469 (26%)
ESL1	NP_849618.1	MFS	36..457	CDD:119392	118/457 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920