DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and AT1G08900

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001077495.1	Gene:	AT1G08900 / 837411	AraportID:	AT1G08900	Length:	462	Species:	Arabidopsis thaliana

Alignment Length:	506	Identity:	131/506 - (25%)
Similarity:	233/506 - (46%)	Gaps:	72/506 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EQHQNLNQNGSESNGKQARIVSGLDRLLKTPPPGEQTRAVRRQVIAVILANVGVFSTGMTLAMPT 67
            |.|. ||:...|::.    ..|||  ||.|               :|::|....:...|:.:.|.
plant     7 ESHL-LNKQEEEASS----FTSGL--LLST---------------SVVVAGSFCYGCAMSYSSPA 49

  Fly    68 ATLHQLKDTTEPVHLNDSQASWFASVNALSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWILL 132
            .:     ...|.:.|:.:..|:|.||..|...|..:.||.:...:||::::.:.:|..|..|:.:
plant    50 QS-----KIMEELGLSVADYSFFTSVMTLGGMITAVFSGKISALVGRRQTMWISDVCCIFGWLAV 109

  Fly   133 ATPSESDQNAFFWQLIV---SRFMLGVGMGLASAPPGVYAAEISVPKT-RGSLILGTSISVAGGI 193
                     ||...:|:   .|..||.|:||.|....||.|||: ||| ||.......:....||
plant   110 ---------AFAHDIIMLNTGRLFLGFGVGLISYVVPVYIAEIT-PKTFRGGFSYSNQLLQCLGI 164

  Fly   194 TILYGIGYCIRDDFRLIALICCGYQLVALLCVLPLPESHCWLLSKKRVTEAKRSLNYFRGFNKSD 258
            ::::..|....  :|.:||:........::|:..:|||..||....:..|.:.||...||.| ||
plant   165 SLMFFTGNFFH--WRTLALLSAIPSAFQVICLFFIPESPRWLAMYGQDQELEVSLKKLRGEN-SD 226

  Fly   259 EITHPQVLEEFQLLQKSLQQRNTAVKESFW-RNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFA 322
            .:.....:.|  .::.|.::..:.:::.|. .|.|.      |:|.:.|...||..|...:..:|
plant   227 ILKEAAEIRE--TVEISRKESQSGIRDLFHIGNAHS------LIIGLGLMLLQQFCGSAAISAYA 283

  Fly   323 VQISQEAGIEID---PFMCAVLI--GLARLITTCPMGYILEWWGRRRAGIISTLGMSVCMFLLAG 382
            .:|..:||...|   ..:..:||  .:..::|       ::.||||...:||::||.:|.|.: |
plant   284 ARIFDKAGFPSDIGTTILAVILIPQSIVVMLT-------VDRWGRRPLLMISSIGMCICSFFI-G 340

  Fly   383 HSQI-----EILKEVPYLPVVAIVGFIVLSTLGLYTLPFFMISELFPQKVRGPASGLTVAVGMFI 442
            .|..     |..|....:.:|.:||::....:||..||:.::||:||..|:..|..|......|.
plant   341 LSYYLQKNGEFQKLCSVMLIVGLVGYVSSFGIGLGGLPWVIMSEIFPVNVKITAGSLVTMSNWFF 405

  Fly   443 SFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIE 493
            :::::.::..:.:: ..|..:.||..::|..::|::..:|||:.|||.||:
plant   406 NWIIIYSFNFMIQW-SASGTYFIFSGVSLVTIVFIWTLVPETKGRTLEEIQ 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	112/444 (25%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	118/449 (26%)
AT1G08900	NP_001077495.1	MFS_GLUT6_8_Class3_like	26..453	CDD:340916	121/476 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920