DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and STP11

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_197718.1	Gene:	STP11 / 832391	AraportID:	AT5G23270	Length:	514	Species:	Arabidopsis thaliana

Alignment Length:	493	Identity:	122/493 - (24%)
Similarity:	209/493 - (42%)	Gaps:	105/493 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 LHQLKD----TTEPVHLNDSQASWFASVNALSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWI 130
            |.|:::    .||....::...:.|.|...|:|.....|:..:....|||.|:::.::..:...:
plant    63 LRQMQNKRGRETEYCKYDNELLTLFTSSLYLAALFASFLASTITRLFGRKVSMVIGSLAFLSGAL 127

  Fly   131 L--LATPSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLILGTSISVAGGI 193
            |  ||...|        .||:.|..||||:|.|:....:|.:|::..|.||:|.:|..:::..||
plant   128 LNGLAINLE--------MLIIGRLFLGVGVGFANQSVPLYLSEMAPAKIRGALNIGFQLAITIGI 184

  Fly   194 -----------TILYGIGYCIRDDFRLIALICCGYQLVALL--CVLPLPESHCWLLSKKRVTEAK 245
                       .:..|||:       .::|...|...|.:|  |.. ||::...:|.:....:||
plant   185 LAANIVNYVTPKLQNGIGW-------RLSLGLAGVPAVMMLVGCFF-LPDTPNSILERGNKEKAK 241

  Fly   246 RSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTAVKESFWRNLHEPEVYKPLVILMSLFA-F 309
            ..|...||   :.|:.|     ||..|..:.:... .||.. |.|:.:.. |:|.:...:... |
plant   242 EMLQKIRG---TMEVEH-----EFNELCNACEAAK-KVKHP-WTNIMQAR-YRPQLTFCTFIPFF 295

  Fly   310 QQLTGIFVVIVFAVQISQEAGIEID-PFMCAVLIGLARLITTCPMGYILEWWGRRRAGIISTLGM 373
            ||||||.|::.:|..:.:..|...| ..:.||:.||..:::|....|.::.:|||
plant   296 QQLTGINVIMFYAPVLFKTIGFGNDASLISAVITGLVNVLSTIVSIYSVDKFGRR---------- 350

  Fly   374 SVCMFLLAGHSQIEILKEVPYLPVVAIVGF----------------IVLSTLGLYT--------- 413
              .:||..|...|     |..:.|.:::|:                |:|:.:.||.
plant   351 --ALFLQGGFQMI-----VTQIAVGSMIGWKFGFNGEGNLSGVDADIILALICLYVAGFAWSWGP 408

  Fly   414 LPFFMISELFPQKVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGV------MALF 472
            |.:.:.||:.|.::|.....|.|:|.||.:|.       |.::.....|.:.||:      |.|.
plant   409 LGWLVPSEICPLEIRSAGQSLNVSVNMFFTFF-------IGQFFLTMLCHMKFGLFYFFAGMVLI 466

  Fly   473 ALIFVYLALPETRRRTLLEIEEQFRSGR--SKSQNQAD 508
            ..||:|..||||:...:.|:.:.::..|  .|..|..|
plant   467 MTIFIYFLLPETKGVPIEEMGKVWKEHRYWGKYSNNDD 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	112/460 (24%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	118/477 (25%)
STP11	NP_197718.1	Sugar_tr	28..490	CDD:278511	118/477 (25%)
STP11	NP_197718.1	MFS	79..474	CDD:119392	109/445 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820