DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and PGLCT

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_568328.1	Gene:	PGLCT / 831472	AraportID:	AT5G16150	Length:	546	Species:	Arabidopsis thaliana

Alignment Length:	545	Identity:	131/545 - (24%)
Similarity:	235/545 - (43%)	Gaps:	104/545 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 NGSESNGKQ-ARIVSGLDRLLKTPPPGEQTRAVRRQVIA-----------------------VIL 51
            :|||:.|.. ||..:|:..::..  ...:.|:||.|..:                       |.:
plant    49 SGSEAMGATLARADNGIQSVMSF--SSVKARSVRAQASSDGDEEEAIPLRSEGKSSGTVLPFVGV 111

  Fly    52 ANVGVFSTGMTLAMPTATLHQL-KDTTEPVHLNDSQASWFASVNALSAPIGGLLSGFLLDRIGRK 115
            |.:|....|..|.:....|..| ||.  .:..|.....|..|.....|.:|....|.|.|:.||.
plant   112 ACLGAILFGYHLGVVNGALEYLAKDL--GIAENTVLQGWIVSSLLAGATVGSFTGGALADKFGRT 174

  Fly   116 KSLIVLNVLIILAWILLATPSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGS 180
            ::..:..:.:.:...|.|| ::|.|.     :||.|.:.|:|:|::||...:|.:|||..:.||:
plant   175 RTFQLDAIPLAIGAFLCAT-AQSVQT-----MIVGRLLAGIGIGISSAIVPLYISEISPTEIRGA 233

  Fly   181 LILGTSISVAGGITILYGIGYCIRDDFRLIALICCGYQLVALLCVLPL----------------- 228
            |         |.:..|:               ||.|. |.||:..|||
plant   234 L---------GSVNQLF---------------ICIGI-LAALIAGLPLAANPLWWRTMFGVAVIP 273

  Fly   229 -----------PESHCWLLSKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTA 282
                       |||..||:.:.:|:||::::....|..:..|:..          ..|...:.::
plant   274 SVLLAIGMAFSPESPRWLVQQGKVSEAEKAIKTLYGKERVVELVR----------DLSASGQGSS 328

  Fly   283 VKESFWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLARL 347
            ..|:.|.:|.....:|.:.:..:||.||||.||..|:.::..:.:.|||:.| ...:.|:|.:.:
plant   329 EPEAGWFDLFSSRYWKVVSVGAALFLFQQLAGINAVVYYSTSVFRSAGIQSD-VAASALVGASNV 392

  Fly   348 ITTCPMGYILEWWGRRRAGIISTLGMSVCMFLLAGHSQIEILKEVPYLPVVAIVGFI--VLS-TL 409
            ..|.....:::..||:...:.|..||::.|.||:.....:.|  ..|...:|:||.:  ||| :|
plant   393 FGTAVASSLMDKMGRKSLLLTSFGGMALSMLLLSLSFTWKAL--AAYSGTLAVVGTVLYVLSFSL 455

  Fly   410 GLYTLPFFMISELFPQKVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFAL 474
            |...:|..::.|:|..::|..|..|::.:....:||:...:..:....|:|:.::.|..:.:.|:
plant   456 GAGPVPALLLPEIFASRIRAKAVALSLGMHWISNFVIGLYFLSVVTKFGISSVYLGFAGVCVLAV 520

  Fly   475 IFVYLALPETRRRTLLEIEEQFRSG 499
            :::...:.||:.|:|.|||....||
plant   521 LYIAGNVVETKGRSLEEIELALTSG 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	111/461 (24%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	115/467 (25%)
PGLCT	NP_568328.1	MFS	109..524	CDD:119392	111/460 (24%)
PGLCT	NP_568328.1	Sugar_tr	111..539	CDD:278511	115/473 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810