DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and PMT6

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_195385.1	Gene:	PMT6 / 829820	AraportID:	AT4G36670	Length:	493	Species:	Arabidopsis thaliana

Alignment Length:	512	Identity:	129/512 - (25%)
Similarity:	224/512 - (43%)	Gaps:	57/512 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 DRLLKTPPPGEQTRAVRRQVIAVILANVGVFSTGMTLAMPTATLHQLKDTTEPVHLNDSQASWFA 91
            |::....|.|....|::..::|.|::.:..:.||:   |..|.:.    ..|.:..||.|.....
plant     3 DQISGEKPAGVNRFALQCAIVASIVSIIFGYDTGV---MSGAMVF----IEEDLKTNDVQIEVLT 60

  Fly    92 SVNALSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFW-----QLIVSR 151
            .:..|.|.:|.||:|...|.|||:.::::.::|.:|..||:.           |     .|:..|
plant    61 GILNLCALVGSLLAGRTSDIIGRRYTIVLASILFMLGSILMG-----------WGPNYPVLLSGR 114

  Fly   152 FMLGVGMGLASAPPGVYAAEISVPKTRGSLILGTSISVAGGITILYGIGYC-----IRDDFRLIA 211
            ...|:|:|.|.....||:|||:....||.|.....:.::.||.:.|.:.|.     :...:||:.
plant   115 CTAGLGVGFALMVAPVYSAEIATASHRGLLASLPHLCISIGILLGYIVNYFFSKLPMHIGWRLML 179

  Fly   212 LICCGYQLVALLCVLPLPESHCWLLSKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSL 276
            .|.....||....:|.:|||..||:.:.|:.|.|..|.......:..|:....:.....:..|.:
plant   180 GIAAVPSLVLAFGILKMPESPRWLIMQGRLKEGKEILELVSNSPEEAELRFQDIKAAAGIDPKCV 244

  Fly   277 QQRNTAVK--------ESFWRNL---HEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAG 330
               :..||        |..|:.|   ..|.|.:.|:..:.:..||..:||..|:::..:|.::||
plant   245 ---DDVVKMEGKKTHGEGVWKELILRPTPAVRRVLLTALGIHFFQHASGIEAVLLYGPRIFKKAG 306

  Fly   331 IEIDPFMCAVLIGLARLITT--CPMGYILEWWGRRRAGIISTLGMSVCMFLL---------AGHS 384
            |.....:..|.||:..:.||  .....:|:..|||:..:.|..||.:.:.:|         ||..
plant   307 ITTKDKLFLVTIGVGIMKTTFIFTATLLLDKVGRRKLLLTSVGGMVIALTMLGFGLTMAQNAGGK 371

  Fly   385 QIEILKEVPYLPVVAIVGFIVLSTLGLYTLPFFMISELFPQKVRGPASGLTVAVGMFISFVVLKT 449
                |.....|.:||...|:...::||..:.:...||:||.|:|...:.|.|||...::..|..:
plant   372 ----LAWALVLSIVAAYSFVAFFSIGLGPITWVYSSEVFPLKLRAQGASLGVAVNRVMNATVSMS 432

  Fly   450 YPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQFRSGRSKSQNQ 506
            :..:...:.....|.:|..:|..|..|.:..||||:.::|.|||..|:....|.:.:
plant   433 FLSLTSAITTGGAFFMFAGVAAVAWNFFFFLLPETKGKSLEEIEALFQRDGDKVRGE 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	114/461 (25%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	120/467 (26%)
PMT6	NP_195385.1	Sugar_tr	20..479	CDD:278511	123/483 (25%)
PMT6	NP_195385.1	MFS	22..463	CDD:119392	115/465 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820