DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and STP12

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_193879.4	Gene:	STP12 / 828233	AraportID:	AT4G21480	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	532	Identity:	137/532 - (25%)
Similarity:	223/532 - (41%)	Gaps:	123/532 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PGEQTRAVRRQVIAVILANVG--VF------STGMTLA-------MPTATLHQLK--DTTEPVHL 82
            ||:.|..|   .:..|:|.:|  :|      |.|:|..       .|:....|.|  |:.:....
plant    16 PGKLTLYV---TVTCIVAAMGGLIFGYDIGISGGVTTMDSFQQKFFPSVYEKQKKDHDSNQYCRF 77

  Fly    83 NDSQASWFASVNALSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAF---F 144
            :....:.|.|...|:|....|::.::..:.|||.|:::..||.....:|         |.|   .
plant    78 DSVSLTLFTSSLYLAALCSSLVASYVTRQFGRKISMLLGGVLFCAGALL---------NGFATAV 133

  Fly   145 WQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLILGTSISVAGGITILYGIGYCIRDDFRL 209
            |.|||.|.:||.|:|..:....:|.:|::..|.||:|.:|..:|:..||.:...:.:       .
plant   134 WMLIVGRLLLGFGIGFTNQSVPLYLSEMAPYKYRGALNIGFQLSITIGILVANVLNF-------F 191

  Fly   210 IALICCGYQLVALLCVLP----------LPESHCWLLSKKRVTEAKRSLNYFRGFNK-SDEITHP 263
            .:.|..|::|.....|:|          ||::...::.:.:...|:..|...||.:. .|||...
plant   192 FSKISWGWRLSLGGAVVPALIITVGSLILPDTPNSMIERGQFRLAEAKLRKIRGVDDIDDEINDL 256

  Fly   264 QVLEEFQLLQKSLQQRNTAVKESFWRNLHEPEVYKP-LVILMSLFAFQQLTGIFVVIVFAVQISQ 327
            .:..|...|           .|..||||.:.: |:| |.:.:.:.||||||||.|::.:|..:.|
plant   257 IIASEASKL-----------VEHPWRNLLQRK-YRPHLTMAILIPAFQQLTGINVIMFYAPVLFQ 309

  Fly   328 EAGIEID-PFMCAVLIGLARLITTCPMGYILEWWGRRRAGIISTLGMSVCMFLLAGHSQIEILKE 391
            ..|...| ..:.||:.||..:..|....|.::.||||            .:||..|...:
plant   310 TIGFGSDAALISAVVTGLVNVGATVVSIYGVDKWGRR------------FLFLEGGFQML----- 357

  Fly   392 VPYLPVVAIVG-----------------FIVLSTLGLYTLPF---------FMISELFPQKVRGP 430
            :..:.|.|.:|                 .:|:..:.:|...|         .:.||:||.::|..
plant   358 ISQVAVAAAIGAKFGVDGTPGVLPKWYAIVVVLFICIYVAAFAWSWGPLGWLVPSEIFPLEIRSA 422

  Fly   431 ASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFAL------IFVYLALPETRRRTL 489
            |..:||:|.|..:|::.:.:.       |..|.:.||:...||.      |||||.|||||.
plant   423 AQSITVSVNMIFTFLIAQVFL-------MMLCHLKFGLFIFFAFFVVVMSIFVYLFLPETRG--- 477

  Fly   490 LEIEEQFRSGRS 501
            :.|||..|..||
plant   478 VPIEEMNRVWRS 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	120/494 (24%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	125/492 (25%)
STP12	NP_193879.4	MFS_STP	29..474	CDD:340919	122/496 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820