DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and AT2G20780

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_179671.2	Gene:	AT2G20780 / 816607	AraportID:	AT2G20780	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	556	Identity:	138/556 - (24%)
Similarity:	246/556 - (44%)	Gaps:	96/556 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDEQHQNLNQNGSESNGKQARIVSGLDRLLKTPPPGEQTRAVRRQVIA---------VILA-NVG 55
            ||...:. :||..|:..:.:|                    .|:.|:|         |:|. :||
plant    31 MDSDAEE-SQNHREAEARNSR--------------------TRKYVMACAFFASLNNVLLGYDVG 74

  Fly    56 VFSTGMTLAMPTATLHQLKDTTEPVHLNDSQASWFASVNALSAPIGGLLSGFLLDRIGRKKSLIV 120
            |.|..:........:.:::  ||.:         ..|::.:|. .|.|..|...|.||||.:: .
plant    75 VMSGAVLFIQQDLKITEVQ--TEVL---------IGSLSIISL-FGSLAGGRTSDSIGRKWTM-A 126

  Fly   121 LNVLIIL--AWILLATPSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLIL 183
            |..|:..  |.::...||       |..|::.|.:.|:|:||......||.||||....||....
plant   127 LAALVFQTGAAVMAVAPS-------FEVLMIGRTLAGIGIGLGVMIAPVYIAEISPTVARGFFTS 184

  Fly   184 GTSISVAGGITILYGIGYC-----IRDDFR------LIALICCGYQLVALLCVLPLPESHCWLLS 237
            ...|.:..||.:.|...|.     :...:|      ::..:..|:    .|||  :|||..||:.
plant   185 FPEIFINLGILLGYVSNYAFSGLSVHISWRIMLAVGILPSVFIGF----ALCV--IPESPRWLVM 243

  Fly   238 KKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTAVKES--FWRNLHEPE--VYK 298
            |.||..|:..|  .:...:.||       .|.:|.:..|...:|...|.  .||.|..|.  |.|
plant   244 KGRVDSAREVL--MKTNERDDE-------AEERLAEIQLAAAHTEGSEDRPVWRELLSPSPVVRK 299

  Fly   299 PLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCA--VLIGLARLITTCPMGYILEWWG 361
            .|::...:..|||:|||...:.::.:|.:||||:.:..:.|  |.:|:.:.:......::::..|
plant   300 MLIVGFGIQCFQQITGIDATVYYSPEILKEAGIQDETKLLAATVAVGVTKTVFILFATFLIDSVG 364

  Fly   362 RRRAGIISTLGMSVCMFLLA------GHSQIEILKEVPYLPVVAIVGFIVLSTLGLYTLPFFMIS 420
            |:....:||:||::|:|.|:      |...:.|.     |.::.:.|.:...::|:..:.:.:.|
plant   365 RKPLLYVSTIGMTLCLFCLSFTLTFLGQGTLGIT-----LALLFVCGNVAFFSIGMGPVCWVLTS 424

  Fly   421 ELFPQKVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETR 485
            |:||.::|..||.|........|.:|..::..:...:.:...|.:|.:::..::||||:.:|||.
plant   425 EIFPLRLRAQASALGAVGNRVCSGLVAMSFLSVSRAITVGGTFFVFSLVSALSVIFVYVLVPETS 489

  Fly   486 RRTLLEIEEQFRSGRSKSQNQADVEMKEVFVRKPEE 521
            .::|.:||..|:.|..:...:.::...|..|||.:|
plant   490 GKSLEQIELMFQGGLERKDGEVELGDAERLVRKEQE 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	115/455 (25%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	116/460 (25%)
AT2G20780	NP_179671.2	MFS_PLT	61..496	CDD:340995	120/474 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810