DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and PMT1

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_179209.1	Gene:	PMT1 / 816109	AraportID:	AT2G16120	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	538	Identity:	120/538 - (22%)
Similarity:	238/538 - (44%)	Gaps:	62/538 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LNQNGSESNGKQARIVSGLDRLLKTPPPGEQTR-----AVRRQVIAVILA-NVGVFSTGMTLAMP 66
            :|.:|.|    |..:::..:     ||.|.::|     |:...:.::||. ::||.| |.::.
plant     1 MNSSGVE----QGVVIAESE-----PPRGNRSRYAFACAILASMTSIILGYDIGVMS-GASIF-- 53

  Fly    67 TATLHQLKDTTEPVHLNDSQASWFASVNALSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWIL 131
                  :||   .:.|:|.|......:..:.:.:|...:|...|.:||:.::::.........:|
plant    54 ------IKD---DLKLSDVQLEILMGILNIYSLVGSGAAGRTSDWLGRRYTIVLAGAFFFCGALL 109

  Fly   132 LATPSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLILGTSISVAGGITIL 196
            :...:    |..|  ::|.||:.|:|:|.|.....||.||::...:||.|.....|.:..||.:.
plant   110 MGFAT----NYPF--IMVGRFVAGIGVGYAMMIAPVYTAEVAPASSRGFLTSFPEIFINIGILLG 168

  Fly   197 YGIGYCIRD-----DFRLIALICCGYQLVALLCVLPLPESHCWLLSKKRVTEA-----KRSLNYF 251
            |...|....     .:|.:..:.....:...:.||.:|||..||:.:.|:.:|     |.|....
plant   169 YVSNYFFSKLPEHLGWRFMLGVGAVPSVFLAIGVLAMPESPRWLVLQGRLGDAFKVLDKTSNTKE 233

  Fly   252 RGFNKSDEITHPQVLEEFQLLQKSLQQRNTAVKESFWRNL---HEPEVYKPLVILMSLFAFQQLT 313
            ...::.|:|.....:.:.......:.....:..:..|::|   ..|.|...|:..:.:...||.:
plant   234 EAISRLDDIKRAVGIPDDMTDDVIVVPNKKSAGKGVWKDLLVRPTPSVRHILIACLGIHFAQQAS 298

  Fly   314 GIFVVIVFAVQISQEAGIEI--DPFMCAVLIGLAR----LITTCPMGYILEWWGRRRAGIISTLG 372
            ||..|::::..|..:||::.  |..:..|.:|:.:    ::.||    :::.:|||...:.|..|
plant   299 GIDAVVLYSPTIFSKAGLKSKNDQLLATVAVGVVKTLFIVVGTC----VVDRFGRRALLLTSMGG 359

  Fly   373 MSVCMFLLAGHSQI------EILKEVPYLPVVAIVGFIVLSTLGLYTLPFFMISELFPQKVRGPA 431
            |.:.:..|.....:      :.||....|.|..::.|:...::|...:.:...||:||.::|...
plant   360 MFLSLTALGTSLTVINRNPGQTLKWAIGLAVTTVMTFVATFSIGAGPVTWVYCSEIFPVRLRAQG 424

  Fly   432 SGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQF 496
            :.|.|.:...:|.::..|:..:.:.|.:...|::|..:|..|.:|.:..|||||...|.|:|..|
plant   425 ASLGVMLNRLMSGIIGMTFLSLSKGLTIGGAFLLFAGVAAAAWVFFFTFLPETRGIPLEEMETLF 489

  Fly   497 RSGRSKSQNQADVEMKEV 514
            .|..:..:|.:..:..||
plant   490 GSYTANKKNNSMSKDNEV 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	98/455 (22%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	101/460 (22%)
PMT1	NP_179209.1	Sugar_tr	29..489	CDD:278511	107/481 (22%)
PMT1	NP_179209.1	MFS	31..473	CDD:119392	98/463 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900