Protein Alignment CG8249 and SLC2A10

DIOPT Version :9

• Sequence 1: NP_001246349.1
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: XP_011527362.1
• Gene: SLC2A10 / 81031
• HGNCID: 13444
• Length: 562
• Species: Homo sapiens
• Alignment Length: 516
• Identity: 102/516 - (19%)
• Similarity: 182/516 - (35%)
• Gaps: 166/516 - (32%)

  Fly    96 LSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFWQLIVSRFMLGVGMGL 160
            |.|.:..|:.|||:|..|||::::..|::::...:.|..     ..:..| |::.|.::|..:.|
Human    77 LGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL-----AGSLAW-LVLGRAVVGFAISL 135

  Fly   161 ASAPPGVYAAEISVPKTRGSLILGTSISVAGGITILYGIGYCIRDDFRLIALICCGYQLVALLCV 225
            :|....:|.:|:..|:.||.|:......:..||.:.|.:.|.                    |..
Human   136 SSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA--------------------LAG 180

  Fly   226 LPLPESHC--WLLSKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTAVKESF- 287
            .|....|.  |                         .|.|.||:...||........||..:..
Human   181 TPWGWRHMFGW-------------------------ATAPAVLQSLSLLFLPAGTDETATHKDLI 220

  Fly   288 -WRNLHEPEV--YKPLVILMSLF-----------------AFQQLTGIFVVIVFAVQISQEAGIE 332
             .:....|::  .:|....:.||                 .||||||...|:.:|..|....|..
Human   221 PLQGGEAPKLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFH 285

  Fly   333 --IDPFMCAVLIGLARLITTCPMGYILEWWGRRR---AG----IISTLGMSVCMFL--------- 379
              ....:.:|.:|..::..|.....:::..|||.   ||    .:|..|:.:..|.
Human   286 GGSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMALSVSGIGLVSFAVPMDSGPSC 350

  Fly   380 -----------LAGHSQIEILKEVPYLP------------------------------------- 396
                       |.|.|.:.....:|.:|
Human   351 LAVPNATGQTGLPGDSGLLQDSSLPPIPRTNEDQREPILSTAKKTKPHPRSGDPSAPPRLALSSA 415

  Fly   397 ------------------VVAIVGFIVLSTLGLYTLPFFMISELFPQKVRGPA----SGLTVAVG 439
                              ::.::.|:...:.|...:.:.::||::|.::||.|    :....|..
Human   416 LPGPPLPARGHALLRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAAN 480

  Fly   440 MFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQFRSGR 500
            :|||...|.....|    |:|..|:::|:.|:..|.|:||.:|||:.::|.||::||:..|
Human   481 LFISLSFLDLIGTI----GLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKRR 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	91/493 (18%)
		Sugar_tr	60..496	CDD:278511	99/510 (19%)
SLC2A10	XP_011527362.1	Sugar_tr	32..533	CDD:278511	99/510 (19%)
		MFS	35..518	CDD:119392	93/495 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144168
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750