Protein Alignment CG8249 and slc2a1

DIOPT Version :10

• Sequence 1: NP_611060.2
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001072458.1
• Gene: slc2a1 / 779913
• XenbaseID: XB-GENE-5755357
• Length: 492
• Species: Xenopus tropicalis
• Alignment Length: 490
• Identity: 141/490 - (28%)
• Similarity: 238/490 - (48%)
• Gaps: 46/490 - (9%)

  Fly    44 RQVIAVILANVGV----FSTGMTLAMPTATLHQLKDTT------EPVHLNDSQASWFASVNALSA 98
            |.::||..|.:|.    ::||:..| |...:....:.|      ||:..:...:.|..||...|
 Frog    10 RLMLAVCTAVIGSLQFGYNTGVINA-PQEVIEGFYNATWLERYNEPIPESTLTSLWSLSVAIFS- 72

  Fly    99 PIGGLLS----GFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFWQLIVSRFMLGVGMG 159
             :||::.    |..::|.||:.|:::.|||..||.||:..   |.....|..||:.||::|:..|
 Frog    73 -VGGMVGSFSVGLFVNRFGRRNSMLMANVLAFLAAILMGF---SKLAVSFEMLIIGRFVVGLYCG 133

  Fly   160 LASAPPGVYAAEISVPKTRGSLILGT--SISVAGGITI--LYGIGYCIRDDFRLIALICCGYQLV 220
            |.:....:|..|:|....||:  |||  .:.|..||.|  ::|:...:.:|.....|:.|.:...
 Frog   134 LTTGFVPMYVGEVSPTSLRGA--LGTLHQLGVVVGILIAQIFGLKPIMGNDSLWPFLLGCIFIPA 196

  Fly   221 ALLCV-LPL-PESHCWLL-SKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTA 282
            .|.|: ||. |||..:|| ::....:||..|...||  .:|..:..|.::|..  ::.::::...
 Frog   197 ILQCIMLPFCPESPRFLLINRNEEDKAKSVLKKLRG--TTDVSSDLQEMKEES--RQMMREKKVT 257

  Fly   283 VKESFWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLARL 347
            :.|.|    ..|...:|:.|.:.|...|||:||..|..::..|.|:|.:| .|....:..|:...
 Frog   258 ILELF----RSPLYRQPMFIAIILQLSQQLSGINAVFYYSTMIFQKAQVE-QPVYATIGAGIVNT 317

  Fly   348 ITTCPMGYILEWWGRRRAGIISTLGMSVCMFLLA-GHSQIEILKEVPYLPVVAIVGFIVLSTLGL 411
            ..|....:::|..|||...:|...||:||..|:. ..:.::.:..:.||.:|||.||:....:|.
 Frog   318 AFTVVSLFVVERAGRRTLHLIGLGGMAVCAILMTIALALLDSVGGMSYLSIVAIFGFVAFFEIGP 382

  Fly   412 YTLPFFMISELFPQKVRGPASGLTVAVGM---FISFVVLKTYPGIKEYLGMSNCFIIFGVMALFA 473
            ..:|:|:::|||.|   ||........|:   ..:|:|...:..:::..| :..||||.|:.|..
 Frog   383 GPIPWFIVAELFSQ---GPRPAAIAVAGLSNWTSNFIVGMGFQYVEQLCG-AYVFIIFTVLLLIF 443

  Fly   474 LIFVYLALPETRRRTLLEIEEQFRSGRSKSQNQAD 508
            .:|.|..:|||:.||..||..:||.|..:...||:
 Frog   444 FVFTYFKVPETKGRTFDEIASEFRQGEGQMVKQAE 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_611060.2	MFS_GLUT6_8_Class3_like	46..491	CDD:340916	133/469 (28%)
slc2a1	NP_001072458.1	MFS_GLUT_Class1	13..457	CDD:340989	131/464 (28%)