DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and slc2a1

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001072458.1	Gene:	slc2a1 / 779913	XenbaseID:	XB-GENE-5755357	Length:	492	Species:	Xenopus tropicalis

Alignment Length:	490	Identity:	141/490 - (28%)
Similarity:	238/490 - (48%)	Gaps:	46/490 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 RQVIAVILANVGV----FSTGMTLAMPTATLHQLKDTT------EPVHLNDSQASWFASVNALSA 98
            |.::||..|.:|.    ::||:..| |...:....:.|      ||:..:...:.|..||...|
Frog    10 RLMLAVCTAVIGSLQFGYNTGVINA-PQEVIEGFYNATWLERYNEPIPESTLTSLWSLSVAIFS- 72

  Fly    99 PIGGLLS----GFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFWQLIVSRFMLGVGMG 159
             :||::.    |..::|.||:.|:::.|||..||.||:..   |.....|..||:.||::|:..|
Frog    73 -VGGMVGSFSVGLFVNRFGRRNSMLMANVLAFLAAILMGF---SKLAVSFEMLIIGRFVVGLYCG 133

  Fly   160 LASAPPGVYAAEISVPKTRGSLILGT--SISVAGGITI--LYGIGYCIRDDFRLIALICCGYQLV 220
            |.:....:|..|:|....||:  |||  .:.|..||.|  ::|:...:.:|.....|:.|.:...
Frog   134 LTTGFVPMYVGEVSPTSLRGA--LGTLHQLGVVVGILIAQIFGLKPIMGNDSLWPFLLGCIFIPA 196

  Fly   221 ALLCV-LPL-PESHCWLL-SKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTA 282
            .|.|: ||. |||..:|| ::....:||..|...||  .:|..:..|.::|..  ::.::::...
Frog   197 ILQCIMLPFCPESPRFLLINRNEEDKAKSVLKKLRG--TTDVSSDLQEMKEES--RQMMREKKVT 257

  Fly   283 VKESFWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLARL 347
            :.|.|    ..|...:|:.|.:.|...|||:||..|..::..|.|:|.:| .|....:..|:...
Frog   258 ILELF----RSPLYRQPMFIAIILQLSQQLSGINAVFYYSTMIFQKAQVE-QPVYATIGAGIVNT 317

  Fly   348 ITTCPMGYILEWWGRRRAGIISTLGMSVCMFLLA-GHSQIEILKEVPYLPVVAIVGFIVLSTLGL 411
            ..|....:::|..|||...:|...||:||..|:. ..:.::.:..:.||.:|||.||:....:|.
Frog   318 AFTVVSLFVVERAGRRTLHLIGLGGMAVCAILMTIALALLDSVGGMSYLSIVAIFGFVAFFEIGP 382

  Fly   412 YTLPFFMISELFPQKVRGPASGLTVAVGM---FISFVVLKTYPGIKEYLGMSNCFIIFGVMALFA 473
            ..:|:|:::|||.|   ||........|:   ..:|:|...:..:::..| :..||||.|:.|..
Frog   383 GPIPWFIVAELFSQ---GPRPAAIAVAGLSNWTSNFIVGMGFQYVEQLCG-AYVFIIFTVLLLIF 443

  Fly   474 LIFVYLALPETRRRTLLEIEEQFRSGRSKSQNQAD 508
            .:|.|..:|||:.||..||..:||.|..:...||:
Frog   444 FVFTYFKVPETKGRTFDEIASEFRQGEGQMVKQAE 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	126/454 (28%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	130/456 (29%)
slc2a1	NP_001072458.1	MFS_GLUT_Class1	13..457	CDD:340989	131/464 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000