Protein Alignment CG8249 and SLC2A11

DIOPT Version :9

• Sequence 1: NP_001246349.1
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001269793.1
• Gene: SLC2A11 / 66035
• HGNCID: 14239
• Length: 535
• Species: Homo sapiens
• Alignment Length: 460
• Identity: 113/460 - (24%)
• Similarity: 188/460 - (40%)
• Gaps: 81/460 - (17%)

  Fly    27 DRLLKTPPPGEQTRAVRRQVIAVILANV-GVFSTGMTLAMPTA-TLHQLKDTTE----------P 79
            |.|..:..|..|.:. |..::.:..|.: |.|..|..|::..| |||..:.|.|          |
Human     3 DELEPSLRPRTQIQG-RILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLP 66

  Fly    80 VHLNDSQASWFASVNALSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFF 144
            .||.....|...|:..|....|.||:|.|...:||||||:|.|:.::.|.||...   |.:...|
Human    67 DHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGF---SRKAGSF 128

  Fly   145 WQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLILGTSISVAGGITILYGIGYCIRDDFRL 209
            ..:::.|.::||..|::.....:|..|.:..:.||::.:.::|..|.||.:...:|  :|:
Human   129 EMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG--LRE---- 187

  Fly   210 IALICCGYQLVALL---CVLP----------LPESHCWLLSKKRVTEA-KRSLNYFRGFNKSDEI 260
               :..|.|...||   |::|          ||||..:||.....||| ..:|...||  ..|..
Human   188 ---LLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRG--SGDLA 247

  Fly   261 THPQVLEEFQLLQKSLQQRNTAVKESFWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQI 325
            ...:.|||.:...:..:.|..      |.......:.:.:..|:.|.:..:|.|...|..:|..:
Human   248 GELEELEEERAACQGCRARRP------WELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSV 306

  Fly   326 SQEAGIEIDPFMCAVL-IGLARLIT-TCPMGYILEWWGRRRAGIISTLGMSVCMFLLAGHSQIEI 388
            .::||:.......|:: .|...|:| ...:..:.|.|| .:||:.||
Human   307 FRKAGVPEAKIQYAIIGTGSCELLTAVVSVAGVDEGWG-VQAGLTST------------------ 352

  Fly   389 LKEVP-----------YLPVVAIVGFIVLSTLGLYTLPFFMISELFPQKVRGPASGLTVAVGMFI 442
             ...|           ||.:..|..||:...:|...:...:.:|||.|..| ||:.:.....|:|
Human   353 -SPPPRPRQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMAR-PAACMVCGALMWI 415

  Fly   443 SFVVL 447
            ..:::
Human   416 MLILV 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	108/438 (25%)
		Sugar_tr	60..496	CDD:278511	105/426 (25%)
SLC2A11	NP_001269793.1	Sugar_tr	22..428	CDD:278511	108/440 (25%)
		MFS	68..>217	CDD:119392	43/160 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144274
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840