Protein Alignment CG8249 and SLC2A5

DIOPT Version :10

• Sequence 1: NP_611060.2
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_003030.1
• Gene: SLC2A5 / 6518
• HGNCID: 11010
• Length: 501
• Species: Homo sapiens
• Alignment Length: 549
• Identity: 140/549 - (25%)
• Similarity: 250/549 - (45%)
• Gaps: 90/549 - (16%)

  Fly     1 MDEQHQNLNQNGSESNGKQARIVSGLDRLLKTPPPGEQTRAVRRQVIAVILANVG-VFSTGMTLA 64
            |::|.|::         |:.|:...|                   .:|.::|..| .|..|..:|
Human     1 MEQQDQSM---------KEGRLTLVL-------------------ALATLIAAFGSSFQYGYNVA 37

  Fly    65 ---MPTATLHQLKDTT----EPVHLNDSQASWFASVNALSAPIGG----LLSGFLLDRIGRKKSL 118
               .|...:.|..:.|    ....:.|...:...||.....|.||    ||.|.|:::.|||.:|
Human    38 AVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGAL 102

  Fly   119 IVLNVLIILAWILLATPSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLIL 183
            :..|:..|:..||:..   |.....|..:|:||.::|:..|::|....:|..|::....||:|.:
Human   103 LFNNIFSIVPAILMGC---SRVATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGV 164

  Fly   184 GTSISVAGGITI--LYGIGYCIRD-DFRLIALICCGYQLVALLCVLP-LPESHCWLL-SKKRVTE 243
            ...:.:..||.:  ::|:...:.: |...|.|...|......|.:|| .|||..:|| .||....
Human   165 VPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAA 229

  Fly   244 AKRSLNYFRGFNKSD----EITHPQVLEE---FQLLQKSLQQRNTAVKESFWRNLHEPEVYKPLV 301
            ||::|...||::..|    ||......|:   |..:.|..:.|:..     |:          |:
Human   230 AKKALQTLRGWDSVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLR-----WQ----------LL 279

  Fly   302 ILMSLFAFQQLTGIFVVIVFAVQISQEAGI--EIDPFMCAVLIGLARLITTCPMGYILEWWGRRR 364
            .::.|...|||:|:..:..:|.||...||:  |...::.|....:..::|.|.: :::|..|||
Human   280 SIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAV-FVVELLGRR- 342

  Fly   365 AGIISTLGMSVCMF----LLAGHSQIEILKEVPYLPVVAIVGFIVLSTLGLYTLPFFMISELFPQ 425
              ::..||.|:|:.    |.|..:..:.:..:||:.:|.::.:::...||...:|..:|:|:|.|
Human   343 --LLLLLGFSICLIACCVLTAALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQ 405

  Fly   426 KVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLL 490
            ..|..|..:..:|....:|.|...:|.|:|.||..: ||:|.|:.|...|:::|.:|||:.:|.:
Human   406 SSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPYS-FIVFAVICLLTTIYIFLIVPETKAKTFI 469

  Fly   491 EIEEQFRSGRSKSQNQADV-----EMKEV 514
            ||.:.|    :|....::|     |:||:
Human   470 EINQIF----TKMNKVSEVYPEKEELKEL 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_611060.2	MFS_GLUT6_8_Class3_like	46..491	CDD:340916	126/474 (27%)
SLC2A5	NP_003030.1	MFS_GLUT_Class2	23..471	CDD:340990	125/470 (27%)