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Protein Alignment CG8249 and SLC2A5

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001315548.1	Gene:	SLC2A5 / 6518	HGNCID:	11010	Length:	501	Species:	Homo sapiens

Alignment Length:	549	Identity:	140/549 - (25%)
Similarity:	250/549 - (45%)	Gaps:	90/549 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDEQHQNLNQNGSESNGKQARIVSGLDRLLKTPPPGEQTRAVRRQVIAVILANVG-VFSTGMTLA 64
            |::|.|::         |:.|:...|                   .:|.::|..| .|..|..:|
Human     1 MEQQDQSM---------KEGRLTLVL-------------------ALATLIAAFGSSFQYGYNVA 37

  Fly    65 ---MPTATLHQLKDTT----EPVHLNDSQASWFASVNALSAPIGG----LLSGFLLDRIGRKKSL 118
               .|...:.|..:.|    ....:.|...:...||.....|.||    ||.|.|:::.|||.:|
Human    38 AVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGAL 102

  Fly   119 IVLNVLIILAWILLATPSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLIL 183
            :..|:..|:..||:..   |.....|..:|:||.::|:..|::|....:|..|::....||:|.:
Human   103 LFNNIFSIVPAILMGC---SRVATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGV 164

  Fly   184 GTSISVAGGITI--LYGIGYCIRD-DFRLIALICCGYQLVALLCVLP-LPESHCWLL-SKKRVTE 243
            ...:.:..||.:  ::|:...:.: |...|.|...|......|.:|| .|||..:|| .||....
Human   165 VPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAA 229

  Fly   244 AKRSLNYFRGFNKSD----EITHPQVLEE---FQLLQKSLQQRNTAVKESFWRNLHEPEVYKPLV 301
            ||::|...||::..|    ||......|:   |..:.|..:.|:..     |:          |:
Human   230 AKKALQTLRGWDSVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLR-----WQ----------LL 279

  Fly   302 ILMSLFAFQQLTGIFVVIVFAVQISQEAGI--EIDPFMCAVLIGLARLITTCPMGYILEWWGRRR 364
            .::.|...|||:|:..:..:|.||...||:  |...::.|....:..::|.|.: :::|..|||
Human   280 SIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAV-FVVELLGRR- 342

  Fly   365 AGIISTLGMSVCMF----LLAGHSQIEILKEVPYLPVVAIVGFIVLSTLGLYTLPFFMISELFPQ 425
              ::..||.|:|:.    |.|..:..:.:..:||:.:|.::.:::...||...:|..:|:|:|.|
Human   343 --LLLLLGFSICLIACCVLTAALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQ 405

  Fly   426 KVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLL 490
            ..|..|..:..:|....:|.|...:|.|:|.||..: ||:|.|:.|...|:::|.:|||:.:|.:
Human   406 SSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPYS-FIVFAVICLLTTIYIFLIVPETKAKTFI 469

  Fly   491 EIEEQFRSGRSKSQNQADV-----EMKEV 514
            ||.:.|    :|....::|     |:||:
Human   470 EINQIF----TKMNKVSEVYPEKEELKEL 494

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.