Protein Alignment CG8249 and SLC2A2

DIOPT Version :10

• Sequence 1: NP_611060.2
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_000331.1
• Gene: SLC2A2 / 6514
• HGNCID: 11006
• Length: 524
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 129/520 - (24%)
• Similarity: 235/520 - (45%)
• Gaps: 58/520 - (11%)

  Fly    16 NGKQARIVSGLDRLLKTPPPGEQTRAVRRQVIAVILANVGVFSTGMTLAMPTATLHQLKDTTEPV 80
            |..|..|:|....:|..|.  :..:|:...||            ..|..:||.: :.:.....|.
Human    32 NAPQQVIISHYRHVLGVPL--DDRKAINNYVI------------NSTDELPTIS-YSMNPKPTPW 81

  Fly    81 HLNDSQAS-------WFASVNALSAPIGGL----LSGFLLDRIGRKKSLIVLNVLIILAWILLAT 134
            ...::.|:       |..||::.:  :||:    ..|:|.|.:||.|:::|.|:|.::..:|:..
Human    82 AEEETVAAAQLITMLWSLSVSSFA--VGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGF 144

  Fly   135 PSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLILGTSISVAGGITI--LY 197
            ......:..   :|..|.:.|:..||.|....:|..||:....||:|.....:::..||.|  :.
Human   145 SKLGPSHIL---IIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQII 206

  Fly   198 GIGYCIRD-DFRLIALICCGYQ-----LVALLCVLPLPESHCWLLSK-KRVTEAKRSLNYFRGFN 255
            |:.:.:.: |...|.|...|.:     |:...|    |||..:|..| ....:||:||...||:
Human   207 GLEFILGNYDLWHILLGLSGVRAILQSLLLFFC----PESPRYLYIKLDEEVKAKQSLKRLRGY- 266

  Fly   256 KSDEITHPQVLEEFQLLQKSLQQRNTAVKESFWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIV 320
              |::|     ::...::|..::.::..|.|..:........:|:::.:.|...||.:||..:..
Human   267 --DDVT-----KDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFY 324

  Fly   321 FAVQISQEAGIEIDPFMCAVLIGLARLITTCPMGYILEWWGRRRAGIISTLGMSVC-MFLLAGHS 384
            ::..|.|.|||. .|....:.:|...::.|....:::|..|||...:|...||.|| :|:..|..
Human   325 YSTSIFQTAGIS-KPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLV 388

  Fly   385 QIEILKEVPYLPVVAIVGFIVLSTLGLYTLPFFMISELFPQKVRGPASGLTVAVGMFISFVVLKT 449
            .:.....:.|:.::||..|:....:|...:|:||::|.|.|..|..|..:........:|:|...
Human   389 LLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALC 453

  Fly   450 YPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQF--RSGRSKSQNQADVEMK 512
            :..|.::.|....|:..||:..|.| |.:..:|||:.::..||..:|  :|| |..:.:|.||||
Human   454 FQYIADFCGPYVFFLFAGVLLAFTL-FTFFKVPETKGKSFEEIAAEFQKKSG-SAHRPKAAVEMK 516

  Fly   513  512
            Human   517  516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_611060.2	MFS_GLUT6_8_Class3_like	46..491	CDD:340916	111/465 (24%)
SLC2A2	NP_000331.1	MFS_GLUT_Class1	12..490	CDD:340989	118/491 (24%)