DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8249 and slc2a9l1

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001159589.1	Gene:	slc2a9l1 / 565510	ZFINID:	ZDB-GENE-090915-3	Length:	491	Species:	Danio rerio

Alignment Length:	526	Identity:	132/526 - (25%)
Similarity:	242/526 - (46%)	Gaps:	76/526 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LDRLLKTPPPGEQTRAVRRQVIAVILANVGVFSTGM---TLAMPTATLHQLKDTTEPVHL----N 83
            :.||||....|   :||   |:.::|...|.|..|.   :::.||..:....:::...|.    .
Zfish     1 MTRLLKQLAGG---KAV---VLIIVLGFGGSFQNGFHLTSISSPTPYIQSFINSSWTHHYGHIPK 59

  Fly    84 DSQASWFASVNALSAPIGGLLSG----FLLDRIGRKKSLIVLNVLIILAWIL--LATPSESDQNA 142
            :|..::..|.......:|||:..    :|..|:|||::.::.:.:.::|.|:  ::.|:.|
Zfish    60 ESTITFIWSAVVALYGLGGLIGSSSVKYLTRRLGRKRTTLLNSAIAVVASIIMYISKPTYS---- 120

  Fly   143 FFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLILGTSISVA--------GGITILYGI 199
             |..::::||:.|...||......:|..|.|..|.||.::|.::|.:|        .|:..:.|
Zfish   121 -FELILIARFLFGFIAGLGLNVHSIYLGESSPKKIRGVVLLTSAIFLALGKLSGQFAGLREILG- 183

  Fly   200 GYCIRDDFRLIALICCGYQLVALLCVLP-LPESHCWLLSKKRVTE-AKRSLNYFRGFNKSDEITH 262
                |:::..|.|.......|..|.||| ||::..::|.:|..|| .:::|.|..|..:     :
Zfish   184 ----REEWWNILLCFPSVFCVIQLAVLPFLPDAPRYILIEKNNTEQCRKALQYLWGLGE-----Y 239

  Fly   263 PQVLEEFQLLQKSL-QQRNTAVKESFWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQIS 326
            ...:||....|..: :::|.:|.:.    |.:..|...::.|:.|....|.:||..:.:|:..|.
Zfish   240 KMEIEEMSEEQAVIGEKQNMSVLDL----LRDKSVRWQVISLLVLNIGIQFSGISAITIFSFNIF 300

  Fly   327 QEAGIEIDPFMCAVL-IGLARLITTCPMGYILEWWGRRRAGIISTLGMSVCMFL------LAGHS 384
            .||||..|......| ||.:.::.|...|..:|..||:........||||.|.|      |..:|
Zfish   301 LEAGIPEDKIRYVTLGIGASEVLITITCGLFIERVGRKPLMWRGFGGMSVVMALIIVTLYLRDYS 365

  Fly   385 QIEILKEVPYLPVVAIVGFIVL------STLGLYTLPFFMISELFPQKVRGPASGLTVAVGMFIS 443
            .:     :||..|..|..|::.      :|:|.      :.:|:|.|..| ||:.:.:.:..::.
Zfish   366 FV-----IPYFTVFLIFLFMIFYGGGPAATVGA------VCNEMFIQSYR-PAAFVYIGILRWVG 418

  Fly   444 FVVLK-TYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQFRSGRSKSQNQA 507
            |.:|. .:|.:...| .|..|::|..:.|.|.::::..||||:.:|:|||.::|:..|.....:.
Zfish   419 FTLLGFVFPFLIVVL-KSLSFVLFSCICLLAALYIFFILPETKGKTILEISQEFQRIRVCGSTKE 482

  Fly   508 DVEMKE 513
            |....|
Zfish   483 DTMFLE 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	112/467 (24%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	117/473 (25%)
slc2a9l1	NP_001159589.1	Sugar_tr	14..471	CDD:278511	122/491 (25%)
slc2a9l1	NP_001159589.1	MFS	18..455	CDD:119392	112/468 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577006
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850