DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and Slc2a9

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001178480.1	Gene:	Slc2a9 / 501925	RGDID:	1597012	Length:	545	Species:	Rattus norvegicus

Alignment Length:	522	Identity:	151/522 - (28%)
Similarity:	236/522 - (45%)	Gaps:	66/522 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PPPGEQTRAVRR----QVIAVILANVGVFST----GMTLAM---PTATLHQLKDTT------EPV 80
            ||.|.:....||    ....::.|.||.|.:    |..|::   ||..:....:.|      :|:
  Rat    25 PPVGRRGWRPRRTKNWSCSLIVAALVGAFGSSFLYGYNLSVVNAPTPYIKAFYNETWYRRHGQPI 89

  Fly    81 HLNDSQASWFASVNALSAPIGGLLSGFLLDRI----GRKKSLIVLNVLIILAWILLATPSESDQN 141
            ..:.....|..:|:..:  ||||:...::..|    |||.:|:|.|...|.|.:|:|.   |.|.
  Rat    90 DPDTLTLLWSVTVSIFA--IGGLVGTLMVKMIGKFLGRKYTLLVNNGFAISAALLMAC---SLQA 149

  Fly   142 AFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLILGTSISVAGGITI--LYGIGYCIR 204
            ..|..|||.||::||..|:|.:...:|..|||..:.||||...|:|.:..|:..  |.|:...:.
  Rat   150 GTFEMLIVGRFIMGVDGGIALSALPMYLNEISPKEIRGSLGQVTAIFICIGVFSGQLLGLPELLG 214

  Fly   205 DD------FRLIALICCGYQLVALLCVLP-LPESHCWLLSKKR-VTEAKRSLNYFRGFNKSDEIT 261
            .:      |.:|.:     ..:|.|..|| ||||..:||.:|. ...|.::...|.|  |:|.
  Rat   215 KERTWPYLFGVIIV-----PALAQLASLPFLPESPRYLLFEKHDEAGATKAFQTFLG--KADV-- 270

  Fly   262 HPQVLEEFQLLQKSLQQRNTAVKESFWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQIS 326
             .|.|||  .|.:|..|||..: .|.:..|..|.|...::.::...|..||.|:..:..:...|.
  Rat   271 -SQELEE--ALAESRVQRNLRL-VSVFELLRAPFVRWQVITVVITMASYQLCGLNAIWFYTNSIF 331

  Fly   327 QEAGIEID--PFMCAVLIGLARLITTCPMGYILEWWGRRRAGIISTLGMSVCMFLLAGHSQIEIL 389
            .:||:..|  |::.....|:..|.... .|.::|..|||.. :|...|:   |.|..|...:.:.
  Rat   332 GKAGVPQDKIPYITLSTGGIETLAAIF-SGLVIERLGRRPL-LIGGFGL---MALFFGMLTVTLT 391

  Fly   390 KE-----VPYLPVVAIVGFIVLSTLGLYTLPFFMISELFPQKVRGPASGLTVAVGMFISFVVLKT 449
            .:     :|||.:|.|:..|.....|...:||.:..|.|.|..|..|..:...|....:|||...
  Rat   392 LQDQAPWIPYLSIVCILAIIASFCSGPGGIPFILTGEFFQQSERPAAFIIAGTVNWLSNFVVGLL 456

  Fly   450 YPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQFRSGRSKS---QNQADVEM 511
            :|.|::.| .|.||::|..:.:...|:.|..||||:.||..||.:.| :.|:|:   :.:||..|
  Rat   457 FPFIQKSL-ESYCFLVFATICIAGAIYFYFVLPETKNRTHAEISQAF-AKRNKAHPPEVKADSAM 519

  Fly   512 KE 513
            .|
  Rat   520 AE 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	130/463 (28%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	135/465 (29%)
Slc2a9	NP_001178480.1	Sugar_tr	47..502	CDD:278511	139/478 (29%)
Slc2a9	NP_001178480.1	MFS	49..486	CDD:119392	130/460 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338005
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840