DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and CG14160

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_648380.2	Gene:	CG14160 / 39177	FlyBaseID:	FBgn0036066	Length:	483	Species:	Drosophila melanogaster

Alignment Length:	510	Identity:	118/510 - (23%)
Similarity:	203/510 - (39%)	Gaps:	107/510 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 RRQVIAVILANVGVFSTGMTLAMPTATLHQLKDTTEPVHLNDSQA-----SWFASVNALSAPIGG 102
            |.|..::..|::.....||.||.      .:.||.....||:...     |||     :.|.:|.
  Fly    23 RLQFQSMASASIVFVGCGMRLAW------SIFDTPAGKFLNNHNTHNLMMSWF-----IGAAVGA 76

  Fly   103 LLSGFLLDRIGRKKSLIVLNVLIILAWIL-LATPSESDQNAFFWQLIVSRFMLGVGMGLASAPPG 166
            ||:...:.|:.:..:......|:|:|.|| :..|..      |.....|...:|...||......
  Fly    77 LLAALFVQRVTKNVAYTSSGFLMIIAGILNVVLPQH------FLAACYSSVSVGAAYGLTQIQAL 135

  Fly   167 VYAAEISVPKTRGSLILGTSISVAGGITI-------------LYGIGYCIRDDFRLIALICCGYQ 218
            |..:|::....||.|:....|.:..|:.:             |...||.:..| :|..::..|..
  Fly   136 VTGSEVAHKSIRGMLLSCEKIFLWLGVCMQVFYTRVWHNLRPLDTQGYEMHID-QLHGMVLAGLG 199

  Fly   219 LVALLCVLP-LPESHCWLLSKKR---VTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQR 279
            |.|::..|. ..||...||.::|   |.|..::|             |.|...|...|::..:|.
  Fly   200 LGAVILALAHRLESPLLLLHQERDMAVGETLKAL-------------HGQSTTELVRLREDCRQL 251

  Fly   280 NTAVKESFWRNLHEPE---------------VYKPLVILMSLFAFQQLT----GIFVVIVFAVQI 325
            ::|  ..:.|.:.|||               .:|  |:|:..||...::    ..|||:.:
  Fly   252 HSA--RDWERFVEEPEESVADWRVWARRILPFFK--VLLLRCFATLAVSLSYNRAFVVVSW---- 308

  Fly   326 SQEAGIEIDPFMCAVLIGLARLITTCPMGYILEWWGRRRAGIISTLGMSVCMFLLAG-HSQIEIL 389
               .|:|.| ..|...:..|.||.:....::::|.|||:...:|.....|.:.::.| ...:|.:
  Fly   309 ---HGLECD-MNCMYWLAFAGLIGSVLGAFVVDWQGRRKVCSLSLFLAGVVIVMVGGVFDHLESV 369

  Fly   390 KEVPY---LPVVA---------IVGFIVLSTLGLYTLPFFMISELFPQKVRGPASGLTVAVGMFI 442
            |...|   |.|:|         :.|.:.:..| :||...|.|:    .|.|..| |:.:...:..
  Fly   370 KRSFYDINLLVIALLMLLFEVIVAGGVAVPAL-VYTAEAFSIA----HKARCLA-GILIVEQLLQ 428

  Fly   443 SFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQFR 497
            ..::|.|:   :.|:.:|..|...||.:....:.|::.:||||:.||.|...:|:
  Fly   429 LGLLLATF---EHYITVSVFFFTIGVFSFIVGLTVFMFMPETRQLTLYECLLKFK 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	108/484 (22%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	114/490 (23%)
CG14160	NP_648380.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444578
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740