DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8249 and Slc2a10

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001102433.1	Gene:	Slc2a10 / 366251	RGDID:	1306552	Length:	536	Species:	Rattus norvegicus

Alignment Length:	499	Identity:	110/499 - (22%)
Similarity:	199/499 - (39%)	Gaps:	136/499 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 LSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFWQLIVSRFMLGVGMGL 160
            |.|.:..|:.|||:|..||:::::..||:::...::|..     ..:..| |::.|..:|..:.|
  Rat    56 LGAFLASLVGGFLIDCYGRRRAILGSNVVLLAGSLILGL-----AGSLPW-LLLGRSSVGFAISL 114

  Fly   161 ASAPPGVYAAEISVPKTRGSLILGTSISVAGGITILYGIGYCI-------RDDFRLIALICCGYQ 218
            :|....:|.:|:..|:.||.|:....:.:..||...||:.|.:       |..|...|
  Rat   115 SSMACCIYVSELVGPRQRGVLVSLYEVGITVGILFSYGLNYVLAGSPWGWRHMFGWAA------- 172

  Fly   219 LVALLCVLPLPESHCWLLSKKRVTEAKRSLNYFRGFNKSD-EITHPQ--VLEEFQLLQKSLQQRN 280
            ..|||..|.|    .:|.:....|.|::.|...:|...|. .:...|  .|:.|:
  Rat   173 APALLQSLSL----FFLPAGAEGTAARQDLIPLQGGETSKLGLVKAQYTFLDLFR---------- 223

  Fly   281 TAVKESFWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIE--IDPFMCAVLIG 343
              .::..|..         .|:.:.|..||||||...|:.:|..|.:..|..  ....:.:|.:|
  Rat   224 --AQDGMWSR---------TVVGLGLVLFQQLTGQPNVLYYASTIFRSVGFHGGSSAVLASVGLG 277

  Fly   344 LARLITTCPMGYILEWWGRR---------RAGIISTLGM-SVCMFLLAGHS---------QIEI- 388
            ..:::.|.....:::..|||         .|..:|.:|: |..:.|.:|.|         |:::
  Rat   278 TVKVVATLIATGLVDRVGRRALLLSGCALMALSVSGIGLVSFAVSLDSGPSCLATSNTSQQVDLP 342

  Fly   389 ---------------------------LKEVPYLPV----------------------------- 397
                                       :.|.|..||
  Rat   343 QTPGLLVRTSLPPVLHTSGDQGQPVRSVTERPIHPVITASLGPALNIDSSVPTSPIPEHTLLCWS 407

  Fly   398 --VAIVGFIVLSTLGLYTLPFFMISELFPQKVRGPA----SGLTVAVGMFISFVVLKTYPGIKEY 456
              |.::.::...:.|...:.:.::||::|.::||.|    |....|..:|||...|.....|
  Rat   408 ALVCMMVYVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCSSFNWAANLFISLSFLDLIGAI--- 469

  Fly   457 LGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQFRSGR 500
             |::..|:::|:.|:..|.|:||.:|||:.::|.|||:||:..|
  Rat   470 -GLAWTFLLYGLTAVLGLAFIYLLVPETKGQSLAEIEQQFQMRR 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	98/476 (21%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	107/493 (22%)
Slc2a10	NP_001102433.1	Sugar_tr	11..508	CDD:278511	107/493 (22%)
Slc2a10	NP_001102433.1	MFS	14..>330	CDD:119392	72/311 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337913
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750