DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and CG3285

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster

Alignment Length:	474	Identity:	114/474 - (24%)
Similarity:	205/474 - (43%)	Gaps:	52/474 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RAVRRQVIAVILANVGVFSTGMTLAMPTATLHQLKDTTEPVH--LNDSQASWFASVNALSAPIGG 102
            |.:|.|.:..:|.|:..||.|:.:...:..:..|:....|:.  :..||.||..|:..:.:.:|.
  Fly    20 RRIRHQFLVTLLLNIATFSHGLGVGWMSPVMRDLQTDESPLDFPVLVSQVSWIGSLVGIGSVMGN 84

  Fly   103 LLSGFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFWQ----LIVSRFMLGVGMGLASA 163
            |::|.|:||||||..|..:.:.....|.|:          :|.|    |.:.|.|.|:..|....
  Fly    85 LIAGLLMDRIGRKMVLFFIAIPYTTFWCLI----------YFVQSVEFLYIGRLMAGITGGACYV 139

  Fly   164 PPGVYAAEISVPKTRGSL----ILGTSISVAGGITILYGIGYCIRDDFRLIALICCGYQLVALLC 224
            ....:.:||:....||.|    :|..:..|..|..:...:.|.....| :|.|..|.:     :|
  Fly   140 VLPTFISEIADTNVRGRLGSIILLSVNTGVLAGYIVSTRVDYFTSPPF-IIGLPVCYF-----IC 198

  Fly   225 VLPLPESHCWLLSKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTAVKESF-W 288
            ...:||:...|:.|.:...||||..:::...|:|    .:..:||:.::..|.:..|...:|| :
  Fly   199 NFLIPETPHHLVRKGKFEAAKRSFMFYKNIRKND----IKAEDEFEEMKYLLIKEQTEKAKSFDY 259

  Fly   289 RNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLARLITTCPM 353
            |:......:|.......|....|.:..|.|..:...:...:...::..||.::||:.:::.....
  Fly   260 RDFITRPAFKAYASAAVLLISNQFSASFCVTTYLADVFAASHTTLNLGMCTIIIGVLQIVGNYVT 324

  Fly   354 GYILEWWGRRRAGIISTLGMSVCMFLLAG---HSQIEILKEVPYLPVVAIVGFIVLSTLGLYTLP 415
            ..:.:.:|||...:.||||.|||:.....   .::...|..|.:||:|.:..|:.|..:||....
  Fly   325 TLLCDKYGRRILMLTSTLGASVCLTAFGTFTFFAEAADLSSVDWLPLVILSCFVFLCNIGLVGCL 389

  Fly   416 FFMISELFPQKVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGV---------MAL 471
            |.::.||||.|:|..:....|.:.....|:.||.:|         .|..::|.         :..
  Fly   390 FVVLVELFPAKIRSVSVSTFVVILSSTVFLTLKIFP---------ICMAVWGTSVTMWSCSGITF 445

  Fly   472 FALIFVYLALPETRRRTLL 490
            |:.::....|.||..::||
  Fly   446 FSFLYFCFFLEETNGKSLL 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	106/452 (23%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	107/454 (24%)
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	105/442 (24%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	98/406 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444493
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	6	5.850