DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and CG15406

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_608761.2	Gene:	CG15406 / 33542	FlyBaseID:	FBgn0031517	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	478	Identity:	109/478 - (22%)
Similarity:	214/478 - (44%)	Gaps:	53/478 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 RRQVIAVILANVGVFSTGMTLAMPTATLHQL---KDTTEPVHLNDSQASWFASVNALSAPIGGLL 104
            |||::..:.|.:..|..|:.|...:..|.:|   ::|....:::.::|||..:|.::....|...
  Fly    16 RRQLLVSLSATLITFCHGIALGWLSPMLPKLLSPQETPLSFYIDVNEASWLGAVISIGGISGNFS 80

  Fly   105 SGFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFWQ----LIVSRFMLGV-GMGLASAP 164
            ..:|::|.|||.|:..|.|.....|.|.          :|.|    |.|:|...|: |.|:....
  Fly    81 FSYLMNRFGRKVSIYALAVPHTCIWFLF----------YFAQSIEWLYVARVFAGLTGGGMFVVL 135

  Fly   165 PGVYAAEISVPKTRGSLILGTSISVAGGITILYGIGYCIRDD--FRLIALICCGYQLVALLCVLP 227
            | ::..||:....||.|....::::..||.    :|:.:...  :.:|.....|..::.:|....
  Fly   136 P-IFIGEIADNSIRGRLCSFFTLTMNTGIM----VGFVVSSHIAYHVIPCAVVGLPVLYVLLATR 195

  Fly   228 LPESHCWLLSKKRVTEAKRSLNYFR-----GFNKSDEITHPQVLEEFQLLQKSLQQRNTAVKES- 286
            .||....|:..||..||::||.|:|     ..:|.:|..:.:..:|.:|   ::||:|....::
  Fly   196 YPEPPQQLIRWKREEEAEKSLRYYRRCDGPNVSKEEERAYQKHFDEMRL---AIQQQNNDTDDNG 257

  Fly   287 -------FWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGL 344
                   ..|:|      |.|...:.|......||.|....:...|......::||....::||.
  Fly   258 LSMSDFLTKRSL------KALATGLVLMVANIFTGTFAFNNYMSNIFDAVHTQLDPNTNTIIIGA 316

  Fly   345 ARLITTCPMGYILEWWGRRRAGIISTLGMSV------CMFLLAGHSQIEILKEVPYLPVVAIVGF 403
            .:::.|....|:::.:||:...|:|..|..:      .....|...::::.....:|||..:...
  Fly   317 VQILGTLASIYLVDRYGRKILLIVSCAGSGIGTSAFGLYAFYAEEQKVDLSAFSAWLPVTLMAFI 381

  Fly   404 IVLSTLGLYTLPFFMISELFPQKVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGV 468
            |.::.:|:.::...::.|:.|||:|..|:...:....|.:|..|||:|.:..:||::........
  Fly   382 IFIANVGVISVTMVVLVEILPQKIRAVATSFCLGCLSFFAFASLKTFPLMMFHLGLAATMWFCAA 446

  Fly   469 MALFALIFVYLALPETRRRTLLE 491
            :::..|.:|.:.|.||:.|::.:
  Fly   447 VSVICLFYVVVCLEETKGRSMYD 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	102/458 (22%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	104/461 (23%)
CG15406	NP_608761.2	MFS	23..458	CDD:119392	102/458 (22%)
CG15406	NP_608761.2	SP	26..466	CDD:273317	104/463 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444503
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	6	5.850