DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and CG33281

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	471	Identity:	121/471 - (25%)
Similarity:	223/471 - (47%)	Gaps:	46/471 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 QVIAVILANVGVFSTGMTLAMPTATLHQLKDTTEPVH---LNDSQASWFASVNALSAPIGGLLSG 106
            |.:|.|..|:...|.|.....|:::..:|.....|:.   |..:...|.||...|...:|..|..
  Fly    10 QYLAAISVNIISISYGAFCGWPSSSFLELSSENSPLDTGPLTPTDQGWVASNICLGGLVGTFLFT 74

  Fly   107 FLLDRIGRKKSLIVLNVLIILAWILL---ATPSESDQNAFFWQLIVSRFMLG-VGMGLASAPPGV 167
            :|.||||||..|:.:.:..:|.|:::   .||         ..||::||:.| .|.|..:..| :
  Fly    75 WLADRIGRKLCLMWMALPNLLGWVIIPFARTP---------MHLIIARFIGGAAGGGCFTVIP-I 129

  Fly   168 YAAEISVPKTRGSLILGTSISVAGGITILYGIGYCIRDDFRLIALICCGYQLVALLCVLPLPESH 232
            |.||::....||.|.:...::...|:.:.:.:||..  ::..::.|......|.:.|...:||:.
  Fly   130 YIAELASDNIRGILGVFLVLTCNFGLVLAFVLGYYF--NYAQVSWIVSSLSFVFVGCFWFMPETP 192

  Fly   233 CWLLSKKRVTEAKRSLNYFRGF--NKSDEITHPQVLEEFQLLQKSLQQRNTAVKES--------- 286
            ..|....::.||:.||.|:|..  |.:.|::     ||.||   .||:..|..|.:
  Fly   193 QHLAKINKIEEAEHSLRYYRNIKSNPAKELS-----EELQL---ELQKLKTTEKTTADGVDDDDA 249

  Fly   287 ----FWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLARL 347
                .|.:..|.:..|..:|.:.|.:|.||.|.|.::.:...|.::||..:.|.:.|:::|:.:|
  Fly   250 ATGVTWSDFAEGKTRKAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQL 314

  Fly   348 ITTCPMGYILEWWGRRRAGIISTLGMSVCMFLLAGHSQIEIL----KEVPYLPVVAIVGFIVLST 408
            :.|.....::|..||:...::|.:|:.:....:..:|..::|    ....::|:......:.|:.
  Fly   315 MGTYASTVLVERLGRKILLLVSAVGIGLGQSAMGTYSYFQMLGCPVASFSWVPIAGFSFMLFLAA 379

  Fly   409 LGLYTLPFFMISELFPQKVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFA 473
            :||.:|||.::||:.|||:|..|..:.::....||...:|..|...|.|||.....:|..::..|
  Fly   380 VGLLSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKLMPVFTESLGMHGTVFMFASLSFLA 444

  Fly   474 LIFVYLALPETRRRTL 489
            .||:.:.:|||:.:::
  Fly   445 AIFIAIFVPETKGKSV 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	116/455 (25%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	116/456 (25%)
CG33281	NP_995620.1	MFS	50..452	CDD:119392	109/421 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444488
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	6	5.850