DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8249 and ght5

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_587740.1	Gene:	ght5 / 2539240	PomBaseID:	SPCC1235.14	Length:	546	Species:	Schizosaccharomyces pombe

Alignment Length:	440	Identity:	102/440 - (23%)
Similarity:	191/440 - (43%)	Gaps:	46/440 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 GGLLSGFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFW-QLIVSRFMLGVGMG-LASA 163
            |..||..|:||||::.|::...::.::..||..|...|      | |::|::...|:.:| |:..
pombe    72 GCFLSSPLMDRIGKRTSIMFWTIVYLIGIILQVTAVPS------WVQIMVAKIWTGLSIGALSVL 130

  Fly   164 PPGVYAAEISVPKTRGSLILGTSISVAGGITILYGIGYCIR---------DDFRLIALICCGYQL 219
            .|| :.:|::....||:::....::|.|||.    |..||.         ..:|:...|...:.:
pombe   131 APG-FQSEVAPADLRGTIVTTYQLAVTGGIF----IAACINMGTHKLHKTAQWRVSMGINLLWGI 190

  Fly   220 VALLCVLPLPESHCWLLSKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTAVK 284
            :..:.:..||||..:|:|..|..||.:.:    ..|....|.|..:..|:.:: ||..:...|..
pombe   191 ITFIGISFLPESPRYLISVGRDEEALQIM----AKNNDLPIEHEVIQTEYHVI-KSDCEAELAGG 250

  Fly   285 ESFWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLARLIT 349
            .:.|..:..|::.....:.:.:.:.|||||......:..::.:..|:. .|::.|:::.....
pombe   251 PATWPEIFGPDIRYRTFLGLGVMSLQQLTGDNYYFYYGFEVFEGTGMN-SPYLSALILDAVNF-- 312

  Fly   350 TCPMG--YILEWWGRRRAGIISTLGMSVCMFLLAGHSQIEILKEVPYLPVVAIVGFIVLSTLGLY 412
            .|..|  ::||::|||...||..|..|:..|:.|......:.::.......|....||.|.|.::
pombe   313 GCTFGGLFVLEFFGRRMPLIIGALWQSITFFIYAAVGNRALTRKNGTSNHRAGAVMIVFSCLFIF 377

  Fly   413 TL-------PFFMISELFPQKVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMA 470
            :.       .:.::.|.:|.:.|...:.:.........|::....|.|...:|....: ||....
pombe   378 SFAQTWGPAAYVIVGESYPIRYRSKCAAVATTGNWLWGFLISFFTPFITNSIGFKYGY-IFAACN 441

  Fly   471 LFALIFVYLALPETRRRTLLEIEEQFRSG------RSKSQNQADVEMKEV 514
            |.|...::|...||:..||.||.|.:.||      |.|:......:.:||
pombe   442 LCAACIIFLFAHETKGLTLEEINELYISGAKPWMPRPKNLGNFTKQQEEV 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	88/397 (22%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	96/414 (23%)
ght5	NP_587740.1	MFS	10..451	CDD:119392	88/398 (22%)
ght5	NP_587740.1	Sugar_tr	11..467	CDD:278511	96/414 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	3	2.810