Protein Alignment CG8249 and hmit-1.1

DIOPT Version :9

• Sequence 1: NP_001246349.1
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_507623.1
• Gene: hmit-1.1 / 180205
• WormBaseID: WBGene00013073
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 603
• Identity: 126/603 - (20%)
• Similarity: 220/603 - (36%)
• Gaps: 143/603 - (23%)

  Fly    24 SGLDRLLKTPPPGEQTRAVRRQVIAVILAN---VGVFSTGMTLAMPTATLHQLKDTTEPVHLNDS 85
            ||.|:...||..|         :...|||.   :|.|..|...::.:|.:..:.|..   .|...
 Worm    10 SGQDKPAHTPKLG---------LFVYILAAASVIGGFLFGYDTSVVSAAMLYMPDAP---GLKPM 62

  Fly    86 QASW---FASVNALSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFWQL 147
            ...|   ..|::...|.:|.|:||...|.|||:|.::..:.:..:..::.|    :..|..  .|
 Worm    63 DTVWQEVLVSISPGMAAVGSLMSGTSSDYIGRRKVILGASAIFTIGALVCA----ASVNKI--ML 121

  Fly   148 IVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLILGTSISVAGGITIL------------YGIG 200
            :|.|.:||:.:|.||....||..|.:....||.|:...::.::.|..:.            |.:|
 Worm   122 LVGRVLLGIAIGFASMIVPVYLGETAPTHVRGMLVAAFALMISFGQVVANITGGAFSYIDPYNVG 186

  Fly   201 YCIRDDFRLIALICCGYQLVALLCVLPLPESHCWLLSKKRVTEAKRSLNYFRGFNKSDEITHPQV 265
            :      ||:........::..:|.:.|||:..||......||.:..|.  :.:|...|....::
 Worm   187 W------RLMFAFAAVPSIIQFVCFMFLPETPRWLYENGFETETREVLE--KVYNGDKEWVEYEM 243

  Fly   266 LE--EFQLLQKSLQQRNTAVKESFWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQE 328
            .|  .|...|....::..|.....||.|..|.|.|...|...|.|||||.||..::.:...|.:.
 Worm   244 AEIIAFNEDQAKENEKAHASGPVIWRILKTPHVLKACFIGSMLQAFQQLAGINTILYYTADIIRS 308

  Fly   329 AGIEID--PFMCAVLIGLARLI-TTCPMGYILEWWGRR-----RAG--IISTLGMSVCMFLLAGH 383
            :||..:  ....:||:.|...| ...||. ::|..|||     ..|  ::|.:.:.|. |||..|
 Worm   309 SGISNNHTTIWISVLLSLCNFIGPFVPMS-LIEKVGRRIIFLFSCGLVVLSLVFIGVA-FLLVNH 371

  Fly   384 SQIEILKEVPY------------------------------------------------------ 394
            .....|....|
 Worm   372 DSAATLPANQYGSNFNSSYPDAKGCMAYSNCDYCVTTDACGFCHDANTKQGYCLPAGFDNPEVYS 436

  Fly   395 -----------------------------LPVVAIVGFIVLSTLGLYTLPFFMISELFPQKVRGP 430
                                         ||::|...:::..:.|..:||:.:.||.:|...|..
 Worm   437 STGSCTNSNGSIANNFKWEKYYCDTKYTLLPIIACGVYLLTFSSGFTSLPWVLNSEFYPMWARST 501

  Fly   431 ASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQ 495
            ...::.......:.::..||..:.:.:|....|.::..:.:.|.||:...:|||:..::.|:|..
 Worm   502 CVAISTTSNWVFNLIIALTYLSLTQVIGKYGAFWLYAGLTVIAFIFILFLVPETKGYSIEEVEML 566

  Fly   496 FRSGRSKSQNQADVEMKE 513
            |.:  .|.:.:|:...:|
 Worm   567 FMN--KKQRREAESRRRE 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	111/542 (20%)
		Sugar_tr	60..496	CDD:278511	111/545 (20%)
hmit-1.1	NP_507623.1	MFS_HMIT_like	31..554	CDD:340918	108/541 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820